H3K27M diffuse midline glioma is homologous recombination defective and sensitized to radiotherapy and NK cell-mediated antitumor immunity by PARP inhibition
H3K27M弥漫性中线胶质瘤存在同源重组缺陷,PARP抑制可使其对放射疗法和NK细胞介导的抗肿瘤免疫更加敏感。
期刊:Neuro-Oncology
影响因子:13.4
doi:10.1093/neuonc/noaf097
Guo, Yupei; Li, Zian; Parsels, Leslie A; Wang, Zhuwen; Parsels, Joshua D; Dalvi, Anushka; The, Stephanie; Hu, Nan; Valvo, Victoria M; Doherty, Robert; Peterson, Erik; Wang, Xinjun; Venkataraman, Sujatha; Agnihotri, Sameer; Venneti, Sriram; Wahl, Daniel R; Green, Michael D; Lawrence, Theodore S; Koschmann, Carl; Morgan, Meredith A; Zhang, Qiang