日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

DRP1 depletion protects NK cells from hypoxia-induced dysfunction

DRP1 缺失可保护 NK 细胞免受缺氧诱导的功能障碍影响。

Verhezen, Tias; Van Den Eynde, Astrid; Verstraelen, Peter; Gehrcken, Laura; Palmiotto, Gabriele; Lau, Ho Wa; De Vos, Winnok H; Van Der Heijden, Sanne; Brants, Louize; Melis, Jöran; Van Audenaerde, Jonas; Rodrigues Fortes, Felicia; Le Compte, Maxim; Roeyen, Geert; Prenen, Hans; Campillo-Davo, Diana; Lion, Eva; Argüello, Rafael J; Van Laere, Steven; Lardon, Filip; Deben, Christophe; Wouters, An; Smits, Evelien; De Waele, Jorrit

The spatial immune landscape predicts outcome and reveals the central role of tumor-associated macrophages in inflammatory breast cancer biology

空间免疫图谱能够预测预后,并揭示肿瘤相关巨噬细胞在炎症性乳腺癌生物学中的核心作用。

Van Berckelaer, Christophe; Van Laere, Steven; Vermeulen, Chloé; Kockx, Mark; Waumans, Yannick; Marien, Koen; Rypens, Charlotte; Missal, Noémie; Berditchevski, Fedor; Bertucci, François; Vermeulen, Peter; Dirix, Luc; Colpaert, Cecile; Devi, Gayathri R; Van Dam, Peter

AAV-mediated delivery of a proliferation inducing ligand (APRIL) to cortical neurons limits inflammation and demyelination in the corpus callosum of the cuprizone mouse model.

通过 AAV 介导将增殖诱导配体 (APRIL) 递送至皮质神经元,可限制铜唑小鼠模型胼胝体中的炎症和脱髓鞘。

Ricciardi Leonardo, Di Marco Federica, Decrop Marion, Di Stefano Julia, Kakunuri Tejaswini, van Rijswijk Joëlle, Vidas-Guscic Nicholas, El Ouaamari Yousra, Bufi Alexandro A, Van Spilbeeck Ignace, Van Audekerke Johan, Faghel Carole, Bartholomeus Esther, Lion Eva, Cools Nathalie, Van Laere Steven, Cicalini Ilaria, De Laurenzi Vincenzo, FitzGerald Una, Pieragostino Damiana, Huard Bertrand, Del Boccio Piero, Ponsaerts Peter, Verhoye Marleen

The Intestinal Mucin Isoform Landscape Reveals Region-Specific Biomarker Panels for Inflammatory Bowel Disease Patient Stratification

肠道粘蛋白同工型图谱揭示了炎症性肠病患者分层的区域特异性生物标志物组合

Arras, Wout; Breugelmans, Tom; Oosterlinck, Baptiste; De Man, Joris G; Malhotra-Kumar, Surbhi; Abrams, Steven; Van Laere, Steven; Macken, Elisabeth; Somers, Michaël; Jauregui-Amezaga, Aranzazu; De Winter, Benedicte Y; Smet, Annemieke

Tractable mouse TNBC models capture the heterogeneous tumor immune microenvironment and adaptation to PD-L1 blockade

易于操作的小鼠TNBC模型能够捕捉到肿瘤免疫微环境的异质性以及对PD-L1阻断的适应性

Salembier, Robbe; De Haes, Caro; Demeyere, Kristel; Van Laere, Steven; Cervenkova, Lucie; Van Renne, Nicolaas; Sotiriou, Christos; Meyer, Evelyne; Steenbrugge, Jonas

Co-targeting of VEGFR2 and PD-L1 promotes survival and vasculature normalization in pleural mesothelioma.

联合靶向 VEGFR2 和 PD-L1 可促进胸膜间皮瘤患者的生存和血管正常化

Rovers Sophie, Van Audenaerde Jonas, Verloy Ruben, De Waele Jorrit, Brants Louize, Hermans Christophe, Lau Ho Wa, Merlin Céline, Möller Ribas Maria, Ponsaerts Peter, Van Laere Steven, Lardon Filip, Wouters An, Fisher Scott A, van Meerbeeck Jan, Marcq Elly, Smits Evelien

Correction: Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer

更正:甲基乙二醛是糖酵解代谢产物,它通过激活MEK/ERK/SMAD1通路引发乳腺癌转移。

Nokin, Marie-Julie; Bellier, Justine; Durieux, Florence; Peulen, Olivier; Rademaker, Gilles; Gabriel, Maude; Monseur, Christine; Charloteaux, Benoit; Verbeke, Lieven; van Laere, Steven; Roncarati, Patrick; Herfs, Michael; Lambert, Charles; Scheijen, Jean; Schalkwijk, Casper; Colige, Alain; Caers, Jo; Delvenne, Philippe; Turtoi, Andrei; Castronovo, Vincent; Bellahcène, Akeila

Neoadjuvant therapy with eribulin, doxorubicin and cyclophosphamide for patients with HER2-negative inflammatory breast cancer: a phase II study

艾立布林、多柔比星和环磷酰胺新辅助治疗HER2阴性炎性乳腺癌患者的II期研究

Fanucci, Kristina; Yeh, Eren D; Shi, Ruichao; Qin, Lei; Bay, Camden P; DiLullo, Molly; Patel, Ashka; Moore, McKenna; Herbert, Zachary T; Harrison, Beth T; Nakhlis, Faina; Bellon, Jennifer; Warren, Laura; Guerriero, Jennifer L; Tolaney, Sara M; Regan, Meredith; Overmoyer, Beth; Van Laere, Steven; Lynce, Filipa

Gradual DNA methylation changes reveal transcription factors implicated in metabolic dysfunction-associated steatotic liver disease progression and epigenetic age acceleration

DNA甲基化的渐进性变化揭示了与代谢功能障碍相关的脂肪肝疾病进展和表观遗传年龄加速有关的转录因子。

Van Dijck, Evelien; Van Laere, Steven; Logie, Emilie; Timmermans, Steven; Fransen, Erik; Ibrahim, Joe; Kendall, Timothy J; Fallowfield, Jonathan A; Mateiu, Ligia M; Libert, Claude; Van Camp, Guy; Verrijken, An; Van Gaal, Luc; Francque, Sven; Van Hul, Wim; Berghe, Wim Vanden

Multiscale Modeling Uncovers Macrophage Infiltration and TNF-α Signaling Networks for Targeting in Inflammatory Breast Cancer Tumor Emboli

多尺度建模揭示巨噬细胞浸润和TNF-α信号网络在炎症性乳腺癌肿瘤栓塞治疗中的靶向作用

Pai, Pritha; Van Berckelaer, Christophe; Van Laere, Steven; Bennion, Alexandra; Charity, Theresa; Yang, Jinming; Bertucci, Francois; Van Dam, Peter; Palmer, Gregory M; McCall, Shannon; Dirix, Luc Y; Ueno, Naoto T; Devi, Gayathri R