日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Protein kinase D displays intrinsic Tyr autophosphorylation activity: insights into mechanism and regulation

蛋白激酶D具有内在的酪氨酸自磷酸化活性:机制和调控机制的深入研究

Cobbaut, Mathias; Derua, Rita; Parker, Peter J; Waelkens, Etienne; Janssens, Veerle; Van Lint, Johan

Function and Regulation of Protein Kinase D in Oxidative Stress: A Tale of Isoforms

氧化应激中蛋白激酶D的功能和调控:同工酶的故事

Cobbaut, Mathias; Van Lint, Johan

Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop

在氧化应激条件下,PKD 同工型的差异性调控是通过 P+1 环中保守酪氨酸残基的磷酸化实现的。

Cobbaut, Mathias; Derua, Rita; Döppler, Heike; Lou, Hua Jane; Vandoninck, Sandy; Storz, Peter; Turk, Benjamin E; Seufferlein, Thomas; Waelkens, Etienne; Janssens, Veerle; Van Lint, Johan

Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyrazolo[3,4-d]pyrimidine analogues

发现一种强效蛋白激酶D抑制剂:吡唑并[3,4-d]嘧啶类似物结合模式的见解

Verschueren, Klaas; Cobbaut, Mathias; Demaerel, Joachim; Saadah, Lina; Voet, Arnout R D; Van Lint, Johan; De Borggraeve, Wim M

Control of MT1-MMP transport by atypical PKC during breast-cancer progression

非典型蛋白激酶C在乳腺癌进展过程中对MT1-MMP转运的调控

Rossé, Carine; Lodillinsky, Catalina; Fuhrmann, Laetitia; Nourieh, Maya; Monteiro, Pedro; Irondelle, Marie; Lagoutte, Emilie; Vacher, Sophie; Waharte, François; Paul-Gilloteaux, Perrine; Romao, Maryse; Sengmanivong, Lucie; Linch, Mark; van Lint, Johan; Raposo, Graça; Vincent-Salomon, Anne; Bièche, Ivan; Parker, Peter J; Chavrier, Philippe

Protein kinase D regulates RhoA activity via rhotekin phosphorylation.

蛋白激酶 D 通过 rhotekin 磷酸化调节 RhoA 活性

Pusapati Ganesh V, Eiseler Tim, Rykx An, Vandoninck Sandy, Derua Rita, Waelkens Etienne, Van Lint Johan, von Wichert Götz, Seufferlein Thomas

Protein kinase D controls actin polymerization and cell motility through phosphorylation of cortactin.

蛋白激酶 D 通过皮质肌动蛋白的磷酸化来控制肌动蛋白聚合和细胞运动

Eiseler Tim, Hausser Angelika, De Kimpe Line, Van Lint Johan, Pfizenmaier Klaus

Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2

CK1 对 Ser244 位点的磷酸化决定了 PKD2 的核定位和底物靶向性。

von Blume, J; Knippschild, Uwe; Dequiedt, Franck; Giamas, Georgios; Beck, Alexander; Auer, Alexandra; Van Lint, Johan; Adler, Guido; Seufferlein, Thomas

Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor

蛋白磷酸酶-1是IRBIT与肌醇1,4,5-三磷酸受体相互作用的一种新型调节因子。

Devogelaere, Benoit; Beullens, Monique; Sammels, Eva; Derua, Rita; Waelkens, Etienne; van Lint, Johan; Parys, Jan B; Missiaen, Ludwig; Bollen, Mathieu; De Smedt, Humbert

Role of the regulatory domain of protein kinase D2 in phorbol ester binding, catalytic activity, and nucleocytoplasmic shuttling

蛋白激酶D2调控结构域在佛波酯结合、催化活性和核质穿梭中的作用

Auer, Alexandra; von Blume, Julia; Sturany, Sabine; von Wichert, Götz; Van Lint, Johan; Vandenheede, Jackie; Adler, Guido; Seufferlein, Thomas