日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Plasmacytoid dendritic cells in the intestine preferentially produce interferon lambda at homeostasis contributing to tonic localized innate immune responses.

肠道中的浆细胞样树突状细胞在体内平衡状态下优先产生干扰素λ,从而促进持续的局部先天免疫反应

Constant David A, Van Winkle Jacob A, Norwood Philip A, Mishra Gargi, Meyer Kimberly A, Laney Margaret E, Madden Shelby R, Griffith Alec, Rodrigues Patrick Fernandes, Savan Ram, Nice Timothy J

Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium.

肠道菌群的稳态干扰素-λ反应刺激肠道上皮特定区域内的先发制人的抗病毒防御

Van Winkle Jacob A, Peterson Stefan T, Kennedy Elizabeth A, Wheadon Michael J, Ingle Harshad, Desai Chandni, Rodgers Rachel, Constant David A, Wright Austin P, Li Lena, Artyomov Maxim N, Lee Sanghyun, Baldridge Megan T, Nice Timothy J

Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells

半胱天冬酶介导的鼠诺如病毒NS1/2的切割可增强细胞凋亡,并且是肠道上皮细胞持续感染所必需的。

Robinson, Bridget A; Van Winkle, Jacob A; McCune, Broc T; Peters, A Mack; Nice, Timothy J

The Role of Interferon in Persistent Viral Infection: Insights from Murine Norovirus

干扰素在持续性病毒感染中的作用:来自小鼠诺如病毒的启示

Nice, Timothy J; Robinson, Bridget A; Van Winkle, Jacob A