日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

GSK3β promotes p53/Nrf2-dependent expression of the stress response protein REDD2 in retinal Müller glia exposed to hyperlipidemic conditions

在暴露于高脂血症条件下的视网膜穆勒胶质细胞中,GSK3β促进p53/Nrf2依赖的应激反应蛋白REDD2的表达。

VanCleave, Ashley M; Sunilkumar, Siddharth; Toro, Allyson L; Kimball, Scot R; Dennis, Michael D

REDD1-dependent GSK3β signaling in podocytes promotes canonical NF-κB activation in diabetic nephropathy

在糖尿病肾病中,足细胞中 REDD1 依赖的 GSK3β 信号通路促进经典 NF-κB 通路的激活。

Sunilkumar, Siddharth; Yerlikaya, Esma I; VanCleave, Ashley; Subrahmanian, Sandeep M; Toro, Allyson L; Kimball, Scot R; Dennis, Michael D

Rapid proteasomal degradation of the stress response protein REDD2 is mediated by the E3 ligase HUWE1

应激反应蛋白REDD2的快速蛋白酶体降解是由E3连接酶HUWE1介导的。

VanCleave, Ashley M; Sunilkumar, Siddharth; McCurry, Christopher M; Toro, Allyson L; Kimball, Scot R; Dennis, Michael D

NLRP3 Inflammasome Priming in the Retina of Diabetic Mice Requires REDD1-Dependent Activation of GSK3β

糖尿病小鼠视网膜中的 NLRP3 炎症小体启动需要 REDD1 依赖的 GSK3β 激活

Christopher M McCurry, Siddharth Sunilkumar, Sandeep M Subrahmanian, Esma I Yerlikaya, Allyson L Toro, Ashley M VanCleave, Shaunaci A Stevens, Alistair J Barber, Jeffery M Sundstrom, Michael D Dennis

Hdac1 and Hdac2 positively regulate Notch1 gain-of-function pathogenic signaling in committed osteoblasts of male mice

Hdac1 和 Hdac2 正向调控雄性小鼠已分化成骨细胞中 Notch1 功能获得性致病信号通路。

Torres, Haydee M; Hinojosa, Leetoria; VanCleave, Ashley M; Rodezno, Tania; Westendorf, Jennifer J; Tao, Jianning

PERK/ATF4-dependent expression of the stress response protein REDD1 promotes proinflammatory cytokine expression in the heart of obese mice

PERK/ATF4 依赖的应激反应蛋白 REDD1 表达促进肥胖小鼠心脏促炎细胞因子表达

Shaunaci A Stevens, Maria K Gonzalez Aguiar, Allyson L Toro, Esma I Yerlikaya, Siddharth Sunilkumar, Ashley M VanCleave, Jessica Pfleger, Elisa A Bradley, Scot R Kimball, Michael D Dennis

REDD1-dependent GSK3β dephosphorylation promotes NF-κB activation and macrophage infiltration in the retina of diabetic mice

REDD1依赖的GSK3β去磷酸化促进糖尿病小鼠视网膜中NF-κB的激活和巨噬细胞的浸润。

Sunilkumar, Siddharth; VanCleave, Ashley M; McCurry, Christopher M; Toro, Allyson L; Stevens, Shaunaci A; Kimball, Scot R; Dennis, Michael D

Müller Glial Expression of REDD1 Is Required for Retinal Neurodegeneration and Visual Dysfunction in Diabetic Mice

糖尿病小鼠视网膜神经退行性变和视觉功能障碍需要穆勒胶质细胞表达REDD1

Miller, William P; Toro, Allyson L; Sunilkumar, Siddharth; Stevens, Shaunaci A; VanCleave, Ashley M; Williamson, David L; Barber, Alistair J; Dennis, Michael D

Activation of Disulfide Redox Switch in REDD1 Promotes Oxidative Stress Under Hyperglycemic Conditions

REDD1 中二硫键氧化还原开关的激活促进高血糖条件下的氧化应激

William P Miller, Congzhou M Sha, Siddharth Sunilkumar, Allyson L Toro, Ashley M VanCleave, Scot R Kimball, Nikolay V Dokholyan, Michael D Dennis

Spleen Tyrosine Kinase Contributes to Müller Glial Expression of Proangiogenic Cytokines in Diabetes

脾脏酪氨酸激酶促进糖尿病中穆勒胶质细胞表达促血管生成细胞因子

Esma I Yerlikaya, Allyson L Toro, Siddharth Sunilkumar, Ashley M VanCleave, Ming Leung, Yuka Imamura Kawasawa, Scot R Kimball, Michael D Dennis