日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Late-Onset Menopause Attenuates Aortic Stiffness in the Postmenopausal Period

晚发性绝经可减轻绝经后主动脉僵硬

Darvish, Sanna; Murray, Kevin O; Mahoney, Sophia A; VanDongen, Nicholas S; Zigler, Melanie C; Ambrose, Charlie; Flickinger, Martinique A; Reisz, Julie A; D'Alessandro, Angelo; Nowak, Kristen L; Clayton, Zachary S; Moreau, Kerrie L; Seals, Douglas R; Rossman, Matthew J

Senolytic Treatment With Fisetin Reverses Age-Related Endothelial Dysfunction Partially Mediated by SASP Factor CXCL12

非瑟酮治疗衰老细胞可逆转年龄相关性内皮功能障碍,部分由SASP因子CXCL12介导

Mahoney, Sophia A; Mazan-Mamczarz, Krystyna; Tsitsipatis, Dimitrios; VanDongen, Nicholas S; Henry-Smith, Charnae'; Okereke, Ada N; Munk, Rachel; Darvish, Sanna; Murray, Kevin O; De, Supriyo; Gorospe, Myriam; Seals, Douglas R; Rossman, Matthew J; Herman, Allison B; Clayton, Zachary S

Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches

间歇性补充非瑟酮可改善衰老骨骼肌的生理功能并减少细胞衰老:与基因清除衰老细胞和合成衰老细胞清除方法的比较

Murray, Kevin O; Mahoney, Sophia A; Ludwig, Katelyn R; Miyamoto-Ditmon, Jill H; VanDongen, Nicholas S; Banskota, Nirad; Herman, Allison B; Seals, Douglas R; Mankowski, Robert T; Rossman, Matthew J; Clayton, Zachary S

The influence of a human macronutrient-matched diet on phenotypes in old mice.

人类宏量营养素匹配饮食对老年小鼠表型的影响

Darrah Mary A, Longtine Abigail G, Greenberg Nathan T, Mahoney Sophia A, Venkatasubramanian Ravinandan, VanDongen Nicholas S, Reisz Julie A, D'Alessandro Angelo, Seals Douglas R, de Quiros Miranda Yara Bernaldo, Clayton Zachary S

Cellular senescence mediates doxorubicin chemotherapy-induced vascular endothelial dysfunction: translational evidence of prevention with senolytic treatment

细胞衰老介导阿霉素化疗引起的血管内皮功能障碍:衰老细胞清除治疗预防的转化证据

Venkatasubramanian, Ravinandan; Mahoney, Sophia A; Hutton, David A; VanDongen, Nicholas S; Brunt, Vienna E; Greenberg, Nathan T; Longtine, Abigail G; Brandt, Lukas; Beyer, Andreas M; Melov, Simon; Rossman, Matthew J; Seals, Douglas R; Clayton, Zachary S

Senolytic treatment with fisetin reverses age-related endothelial dysfunction partially mediated by SASP factor CXCL12.

用非瑟酮进行衰老细胞清除治疗可逆转由 SASP 因子 CXCL12 部分介导的与年龄相关的内皮功能障碍

Mahoney Sophia A, Mazan-Mamczarz Krystyna, Tsitsipatis Dimitrios, VanDongen Nicholas S, Henry-Smith Charnae', Okereke Ada N, Munk Rachel, Darvish Sanna, Murray Kevin O, De Supriyo, Gorospe Myriam, Seals Douglas R, Rossman Matthew J, Herman Allison B, Clayton Zachary S

The bottlenose dolphin (Tursiops truncatus): a novel model for studying healthy arterial aging

宽吻海豚(Tursiops truncatus):研究健康动脉老化的新型模型

Bernaldo de Quirós, Yara; Mahoney, Sophia A; VanDongen, Nicholas S; Greenberg, Nathan T; Venkatasubramanian, Ravinandan; Saavedra, Pedro; Bossart, Greg; Brunt, Vienna E; Clayton, Zachary S; Fernández, Antonio; Seals, Douglas R

Oral Supplementation with the Short-Chain Fatty Acid Acetate Ameliorates Age-Related Arterial Dysfunction in Mice

口服补充短链脂肪酸乙酸酯可改善小鼠的年龄相关性动脉功能障碍

Longtine, Abigail G; Greenberg, Nathan T; Gonzalez, Antonio; Lindquist, Alexandra; VanDongen, Nicholas S; Mahoney, Sophia A; Rahman, Gibraan; Clayton, Zachary S; Ziemba, Brian P; Ludwig, Katelyn R; Widlansky, Michael E; Knight, Rob; Seals, Douglas R; Brunt, Vienna E

Lifelong voluntary aerobic exercise prevents age- and Western diet- induced vascular dysfunction, mitochondrial oxidative stress and inflammation in mice

终身自愿有氧运动可预防小鼠因年龄增长和西方饮食引起的血管功能障碍、线粒体氧化应激和炎症。

Gioscia-Ryan, Rachel A; Clayton, Zachary S; Zigler, Melanie C; Richey, James J; Cuevas, Lauren M; Rossman, Matthew J; Battson, Micah L; Ziemba, Brian P; Hutton, David A; VanDongen, Nicholas S; Seals, Douglas R