日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Short Ileal Microvillus Length Phenotype Associates with Progression from Inflammatory to Complicated Disease Behavior in Pediatric Crohn's Disease

回肠微绒毛长度短表型与儿童克罗恩病从炎症型向复杂性疾病进展相关

Haberman, Yael; Braun, Tzipi; Karns, Rebekah; Bartel, Courtney A; Bonkowski, Erin; Simpson, Katherine F; Walters, Thomas D; Hyams, Jeffrey S; Liu, Ta-Chiang; Kugathasan, Subra; Denson, Lee A; VanDussen, Kelli L

Supplementation with endogenous healthy gut metabolites reverses the disruptions of in vitro and ex vivo epithelial functions induced by fecal content from IBD patients.

补充内源性健康肠道代谢物可逆转 IBD 患者粪便内容物引起的体外和离体上皮功能紊乱。

Abbas-Egbariya Haya, Elwahidi Lubna, Levy David Jessula, Braun Tzipi, Levhar Nina, Hadar Rotem, Efroni Gilat, Granot Maya, Leichtmann-Bardogoo Yael, Maoz Ben M, Weiss Batia, Gal-Mor Ohad, Agranovich Bella, Abramovich Ifat, Denson Lee, Ben-Horin Shomron, VanDussen Kelli L, Amir Amnon, Haberman Yael

The Homeobox Transcription Factor CUX1 Coordinates Postnatal Epithelial Developmental Timing but Is Dispensable for Lung Organogenesis and Regeneration

同源异型盒转录因子CUX1协调出生后上皮发育时序,但对肺器官发生和再生并非必需。

Zhao, Barbara; Socha, Jacob; Toth, Andrea; Fernandes, Sharlene; Warheit-Niemi, Helen; Ruff, Brandy; Khurana Hershey, Gurjit K; VanDussen, Kelli L; Swarr, Daniel; Zacharias, William J

Ileal Paneth Cell Phenotype is a Cellular Biomarker for Pouch Complications in Ulcerative Colitis

回肠潘氏细胞表型是溃疡性结肠炎储袋并发症的细胞生物标志物

Ma, Changqing; Haritunians, Talin; Gremida, Anas K; Syal, Gaurav; Shah, Janaki; Yang, Shaohong; Ramos Del Aguila de Rivers, Claudia; Storer, Chad E; Chen, Ling; Mengesha, Emebet; Mujukian, Angela; Hanna, Mary; Fleshner, Phillip; Binion, David G; VanDussen, Kelli L; Stappenbeck, Thaddeus S; Head, Richard D; Ciorba, Matthew A; McGovern, Dermot P B; Liu, Ta-Chiang

Accessible chromatin maps of inflammatory bowel disease intestine nominate cell-type mediators of genetic disease risk

炎症性肠病肠道的可及染色质图谱揭示了遗传疾病风险的细胞类型介质。

Wayman, Joseph A; Yang, Zi; Angerman, Elizabeth; Bonkowski, Erin; Jurickova, Ingrid; Chen, Xiaoting; Bejjani, Anthony T; Parks, Lois; Parameswaran, Sreeja; Miethke, Alexander G; VanDussen, Kelli L; Dhaliwal, Jasbir; Weirauch, Matthew T; Kottyan, Leah C; Denson, Lee A; Miraldi, Emily R

Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, Crohn's disease, and celiac disease

黏膜转录组学研究揭示了与溃疡性结肠炎、克罗恩病和乳糜泻相关的长链非编码RNA。

Braun, Tzipi; Sosnovski, Katya E; Amir, Amnon; BenShoshan, Marina; VanDussen, Kelli L; Karns, Rebekah; Levhar, Nina; Abbas-Egbariya, Haya; Hadar, Rotem; Efroni, Gilat; Castel, David; Avivi, Camila; Rosen, Michael J; Grifiths, Anne M; Walters, Thomas D; Mack, David R; Boyle, Brendan M; Ali, Syed Asad; Moore, Sean R; Schirmer, Melanie; Xavier, Ramnik J; Kugathasan, Subra; Jegga, Anil G; Weiss, Batya; Mayer, Chen; Barshack, Iris; Ben-Horin, Shomron; Ulitsky, Igor; Beucher, Anthony; Ferrer, Jorge; Hyams, Jeffrey S; Denson, Lee A; Haberman, Yael

Microbiota produced indole metabolites disrupt host cell mitochondrial energy production and inhibit Cryptosporidium parvum growth

微生物群产生的吲哚代谢物会干扰宿主细胞线粒体能量产生,并抑制小隐孢子虫的生长。

Funkhouser-Jones, Lisa J; Xu, Rui; Wilke, Georgia; Fu, Yong; Shriefer, Lawrence A; Makimaa, Heyde; Rodgers, Rachel; Kennedy, Elizabeth A; VanDussen, Kelli L; Stappenbeck, Thaddeus S; Baldridge, Megan T; Sibley, L David

The Promise of Patient-Derived Colon Organoids to Model Ulcerative Colitis

利用患者来源的结肠类器官构建溃疡性结肠炎模型的前景

Ojo, Babajide A; VanDussen, Kelli L; Rosen, Michael J

Epithelial Cell Biomarkers Are Predictive of Response to Biologic Agents in Crohn's Disease

上皮细胞生物标志物可预测克罗恩病对生物制剂的反应

Osterman, Mark T; VanDussen, Kelli L; Gordon, Ilyssa O; Davis, Elisabeth M; Li, Katherine; Simpson, Kate; Ciorba, Matthew; Glover, Sarah C; Abraham, Bincy; Guo, Xueyan; Yee, Eric U; Allard, Felicia D; Perrigoue, Jacqueline G; Claggett, Brian; Shen, Bo; Stappenbeck, Thaddeus S; Liu, Julia J

Epithelial Indoleamine 2,3-Dioxygenase 1 Modulates Aryl Hydrocarbon Receptor and Notch Signaling to Increase Differentiation of Secretory Cells and Alter Mucus-Associated Microbiota

上皮吲哚胺2,3-双加氧酶1通过调节芳烃受体和Notch信号通路促进分泌细胞分化并改变黏液相关微生物群。

Alvarado, David M; Chen, Baosheng; Iticovici, Micah; Thaker, Ameet I; Dai, Nattalie; VanDussen, Kelli L; Shaikh, Nurmohammad; Lim, Chai K; Guillemin, Gilles J; Tarr, Phillip I; Ciorba, Matthew A