日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Insulin treatment normalizes retinal neuroinflammation but not markers of synapse loss in diabetic rats

胰岛素治疗可使糖尿病大鼠的视网膜神经炎症正常化,但不能使突触丢失的标志物正常化

Dustin R Masser, Heather D VanGuilder Starkey, Georgina V Bixler, Wendy Dunton, Sarah K Bronson, Willard M Freeman

Increased hippocampal NgR1 signaling machinery in aged rats with deficits of spatial cognition

空间认知缺陷的老年大鼠海马 NgR1 信号传导机制增强

Heather D VanGuilder Starkey, William E Sonntag, Willard M Freeman

Hippocampal expression of myelin-associated inhibitors is induced with age-related cognitive decline and correlates with deficits of spatial learning and memory.

随着年龄增长,海马体中髓鞘相关抑制剂的表达会逐渐增强,并且与空间学习和记忆缺陷相关

Vanguilder Heather D, Bixler Georgina V, Sonntag William E, Freeman Willard M

Neuroglial expression of the MHCI pathway and PirB receptor is upregulated in the hippocampus with advanced aging.

随着年龄增长,海马体中 MHCI 通路和 PirB 受体的神经胶质表达上调

VanGuilder Starkey Heather D, Van Kirk Colleen A, Bixler Georgina V, Imperio Caesar G, Kale Vijay P, Serfass Jacob M, Farley Julie A, Yan Han, Warrington Junie P, Han Song, Mitschelen Matthew, Sonntag William E, Freeman Willard M

Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment

随着年龄增长,海马体中MHC II通路成分的诱导和胶质细胞活化同时发生,但这与认知障碍无关。

VanGuilder, Heather D; Bixler, Georgina V; Brucklacher, Robert M; Farley, Julie A; Yan, Han; Warrington, Junie P; Sonntag, William E; Freeman, Willard M

Hippocampal dysregulation of synaptic plasticity-associated proteins with age-related cognitive decline

海马突触可塑性相关蛋白失调与年龄相关性认知能力下降

Heather D VanGuilder, Julie A Farley, Han Yan, Colleen A Van Kirk, Matthew Mitschelen, William E Sonntag, Willard M Freeman

The hippocampal neuroproteome with aging and cognitive decline: past progress and future directions

海马神经蛋白质组与衰老和认知衰退的关系:过去的进展和未来的方向

Vanguilder, Heather D; Freeman, Willard M

Plasma proteomic alterations in non-human primates and humans after chronic alcohol self-administration.

非人灵长类动物和人类长期自我摄入酒精后血浆蛋白质组的变化

Freeman Willard M, Vanguilder Heather D, Guidone Elizabeth, Krystal John H, Grant Kathleen A, Vrana Kent E

Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy

对糖尿病视网膜病变大鼠模型中视网膜蛋白表达改变进行多模态蛋白质组学分析

VanGuilder, Heather D; Bixler, Georgina V; Kutzler, Lydia; Brucklacher, Robert M; Bronson, Sarah K; Kimball, Scot R; Freeman, Willard M

Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome

糖尿病的慢性胰岛素治疗并不能完全使视网膜转录组的改变正常化

Georgina V Bixler, Heather D Vanguilder, Robert M Brucklacher, Scot R Kimball, Sarah K Bronson, Willard M Freeman