Vandepoel相关文献与解析，生知库 | 链接生命科学的每一步

Dickmänken, Hannah; Wojno, Marta; Mahieu, Lukas; Theunis, Koen; Ekşi, Eren Can; Christiaens, Valerie; Kempynck, Niklas; De Rop, Florian V; Roels, Natalie; Spanier, Katina I; Vandepoel, Roel; Hulselmans, Gert; Poovathingal, Suresh; Aerts, Stein

细胞生物学

单细胞

发表日期：2026

文献求助收藏

Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation

单细胞空间多组学和深度学习解析肝脏分区中增强子驱动的基因调控网络

期刊:Nature Cell Biology

影响因子:17.3

doi:10.1038/s41556-023-01316-4

Carmen Bravo González-Blas ，Irina Matetovici ，Hanne Hillen ，Ibrahim Ihsan Taskiran ，Roel Vandepoel ，Valerie Christiaens ，Leticia Sansores-García ，Elisabeth Verboven ，Gert Hulselmans ，Suresh Poovathingal ，Jonas Demeulemeester ，Nikoleta Psatha ，David Mauduit ，Georg Halder ，Stein Aerts

Nova-ST: Nano-patterned ultra-dense platform for spatial transcriptomics

Nova-ST：用于空间转录组学的纳米图案化超密平台

期刊:Cell Reports Methods

影响因子:4.3

doi:10.1016/j.crmeth.2024.100831

Suresh Poovathingal, Kristofer Davie, Lars E Borm, Roel Vandepoel, Nicolas Poulvellarie, Annelien Verfaillie, Nikky Corthout, Stein Aerts

信号转导

发表日期：2024

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Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia.

Suz12 失活与 JAK3 突变信号传导协同作用，导致 T 细胞急性淋巴细胞白血病的发生

期刊:Blood

影响因子:23.1

doi:10.1182/blood.2019000015

Broux Michael, Prieto Cristina, Demeyer Sofie, Vanden Bempt Marlies, Alberti-Servera Llucia, Lodewijckx Inge, Vandepoel Roel, Mentens Nicole, Gielen Olga, Jacobs Kris, Geerdens Ellen, Vicente Carmen, de Bock Charles E, Cools Jan

JAK/STAT Pathway Mutations in T-ALL, Including the STAT5B N642H Mutation, are Sensitive to JAK1/JAK3 Inhibitors

T细胞急性淋巴细胞白血病（T-ALL）中的JAK/STAT通路突变，包括STAT5B N642H突变，对JAK1/JAK3抑制剂敏感。

期刊:Hemasphere

影响因子:14.6

doi:10.1097/HS9.0000000000000313

Govaerts, Inge; Jacobs, Kris; Vandepoel, Roel; Cools, Jan

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

TLX1 和 STAT5 协同增强子激活促进 NUP214-ABL1/TLX1 阳性 T 细胞急性淋巴细胞白血病的发展

期刊:Cancer Cell

影响因子:48.8

doi:10.1016/j.ccell.2018.07.007

Marlies Vanden Bempt, Sofie Demeyer, Michaël Broux, Jolien De Bie, Simon Bornschein, Nicole Mentens, Roel Vandepoel, Ellen Geerdens, Enrico Radaelli, Beat C Bornhauser, Andreas E Kulozik, Jules P Meijerink, Jean-Pierre Bourquin, Charles E de Bock, Jan Cools

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

TLX1 和 STAT5 协同增强子激活驱动 NUP214-ABL1/TLX1 阳性 T 细胞急性淋巴细胞白血病的发展

期刊:

影响因子:48.8

doi:PMC6097876

Marlies Vanden Bempt，Sofie Demeyer，Michaël Broux，Jolien De Bie，Simon Bornschein，Nicole Mentens，Roel Vandepoel，Ellen Geerdens，Enrico Radaelli，Beat C Bornhauser，Andreas E Kulozik，Jules P Meijerink，Jean-Pierre Bourquin，Charles E de Bock，Jan Cools

HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development

HOXA9 与激活的 JAK/STAT 信号传导协同作用，促进白血病发展

期刊:Cancer Discovery

影响因子:29.7

doi:10.1158/2159-8290.CD-17-0583

Charles E de Bock, Sofie Demeyer, Sandrine Degryse, Delphine Verbeke, Bram Sweron, Olga Gielen, Roel Vandepoel, Carmen Vicente, Marlies Vanden Bempt, Antonis Dagklis, Ellen Geerdens, Simon Bornschein, Rik Gijsbers, Jean Soulier, Jules P Meijerink, Merja Heinäniemi, Susanna Teppo, Maria Bouvy-Liivran

Malt1 self-cleavage is critical for regulatory T cell homeostasis and anti-tumor immunity in mice

Malt1 自我裂解对小鼠的调节性 T 细胞稳态和抗肿瘤免疫至关重要

期刊:European Journal of Immunology

影响因子:4.5

doi:10.1002/eji.201847597

Mathijs Baens, Rocco Stirparo, Youlia Lampi, Delphine Verbeke, Roel Vandepoel, Jan Cools, Peter Marynen, Charles E de Bock, Simon Bornschein

NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins

NUP214-ABL1 介导的 T 细胞急性淋巴细胞白血病细胞增殖依赖于 LCK 激酶和各种相互作用蛋白

期刊:Haematologica

影响因子:8.2

doi:10.3324/haematol.2013.088674

Kim De Keersmaecker, Michaël Porcu, Luk Cox, Tiziana Girardi, Roel Vandepoel, Joyce Op de Beeck, Olga Gielen, Nicole Mentens, Keiryn L Bennett, Oliver Hantschel

Evaluating single-cell ATAC-seq atlasing technologies using sequence-to-function modeling

利用序列-功能模型评估单细胞ATAC-seq图谱技术

Single-cell spatial multi-omics and deep learning dissect enhancer-driven gene regulatory networks in liver zonation

单细胞空间多组学和深度学习解析肝脏分区中增强子驱动的基因调控网络

Nova-ST: Nano-patterned ultra-dense platform for spatial transcriptomics

Nova-ST：用于空间转录组学的纳米图案化超密平台

Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia.

Suz12 失活与 JAK3 突变信号传导协同作用，导致 T 细胞急性淋巴细胞白血病的发生

JAK/STAT Pathway Mutations in T-ALL, Including the STAT5B N642H Mutation, are Sensitive to JAK1/JAK3 Inhibitors

T细胞急性淋巴细胞白血病（T-ALL）中的JAK/STAT通路突变，包括STAT5B N642H突变，对JAK1/JAK3抑制剂敏感。

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

TLX1 和 STAT5 协同增强子激活促进 NUP214-ABL1/TLX1 阳性 T 细胞急性淋巴细胞白血病的发展

Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia

TLX1 和 STAT5 协同增强子激活驱动 NUP214-ABL1/TLX1 阳性 T 细胞急性淋巴细胞白血病的发展

HOXA9 Cooperates with Activated JAK/STAT Signaling to Drive Leukemia Development

HOXA9 与激活的 JAK/STAT 信号传导协同作用，促进白血病发展

Malt1 self-cleavage is critical for regulatory T cell homeostasis and anti-tumor immunity in mice

Malt1 自我裂解对小鼠的调节性 T 细胞稳态和抗肿瘤免疫至关重要

NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins

NUP214-ABL1 介导的 T 细胞急性淋巴细胞白血病细胞增殖依赖于 LCK 激酶和各种相互作用蛋白