日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MHC2-SCALE enhances identification of immunogenic neoantigens

MHC2-SCALE增强了对免疫原性新抗原的识别

Joshua G Gober ,Aude-Hélène Capietto ,Reyhane Hoshyar ,Martine Darwish ,Richard Vandlen ,Jonathan L Linehan ,Lélia Delamarre ,Adel M ElSohly

Mechanistic Characterization of the Potency of THIOMAB Antibody-Drug Conjugates Targeting Staphylococcus aureus and ETbR-Expressing Tumor Cells Using Quantitative LC-MS/MS Analysis of Intracellular Drug Accumulation

利用定量LC-MS/MS分析细胞内药物积累,对靶向金黄色葡萄球菌和ETbR表达肿瘤细胞的THIOMAB抗体-药物偶联物的效力进行机制表征

Hernandez-Barry, Hilda; Dela Cruz-Chuh, Josefa; Kajihara, Kimberly K; Asundi, Jyoti; Vandlen, Richard; Zhang, Donglu; Hazenbos, Wouter L W; Pillow, Thomas; Liu, Yichin; Wu, Cong; Kozak, Katherine R; Loyet, Kelly M

Epitope mapping of anti-drug antibodies to a clinical candidate bispecific antibody

抗药物抗体与临床候选双特异性抗体的表位映射

Arthur J Schick 3rd, Victor Lundin, Justin Low, Kun Peng, Richard Vandlen, Aaron T Wecksler

Potent Killing of Pseudomonas aeruginosa by an Antibody-Antibiotic Conjugate

抗体-抗生素结合物有效杀死铜绿假单胞菌

Kimberly K Kajihara, Homer Pantua, Hilda Hernandez-Barry, Meredith Hazen, Kiran Deshmukh, Nancy Chiang, Rachana Ohri, Erick R Castellanos, Lynn Martin, Marissa L Matsumoto, Jian Payandeh, Kelly M Storek, Kellen Schneider, Peter A Smith, Michael F T Koehler, Siao Ping Tsai, Richard Vandlen, Kelly M L

Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB-siRNA conjugates

使用 THIOMAB-siRNA 结合物工业平台对抗体介导的 siRNA 递送进行系统评估

Trinna L Cuellar, Dwight Barnes, Christopher Nelson, Joshua Tanguay, Shang-Fan Yu, Xiaohui Wen, Suzie J Scales, Julie Gesch, David Davis, Anja van Brabant Smith, Devin Leake, Richard Vandlen, Christian W Siebel

Structural basis of the broadly neutralizing anti-interferon-α antibody rontalizumab

广谱中和抗干扰素α抗体rontalizumab的结构基础

Brigitte Maurer, Ivan Bosanac, Steven Shia, Mandy Kwong, Racquel Corpuz, Richard Vandlen, Kerstin Schmidt, Charles Eigenbrot

Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation

抗原递送至早期内体消除了人类血液 BDCA3+ 树突状细胞在交叉呈递中的优势

Lillian Cohn, Bithi Chatterjee, Filipp Esselborn, Anna Smed-Sörensen, Norihiro Nakamura, Cécile Chalouni, Byoung-Chul Lee, Richard Vandlen, Tibor Keler, Peter Lauer, Dirk Brockstedt, Ira Mellman, Lélia Delamarre

Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins

新型葡萄球菌糖基转移酶 SdgA 和 SdgB 介导免疫原性和对毒力相关细胞壁蛋白的保护作用

Wouter L W Hazenbos, Kimberly K Kajihara, Richard Vandlen, J Hiroshi Morisaki, Sophie M Lehar, Mark J Kwakkenbos, Tim Beaumont, Arjen Q Bakker, Qui Phung, Lee R Swem, Satish Ramakrishnan, Janice Kim, Min Xu, Ishita M Shah, Binh An Diep, Tao Sai, Andrew Sebrell, Yana Khalfin, Angela Oh, Chris Koth, S

Antibodies against the gH/gL/UL128/UL130/UL131 complex comprise the majority of the anti-cytomegalovirus (anti-CMV) neutralizing antibody response in CMV hyperimmune globulin

针对 gH/gL/UL128/UL130/UL131 复合物的抗体构成了 CMV 高免疫球蛋白中抗巨细胞病毒 (抗 CMV) 中和抗体反应的大部分

Ashley E Fouts, Pamela Chan, Jean-Philippe Stephan, Richard Vandlen, Becket Feierbach

Reorienting the Fab domains of trastuzumab results in potent HER2 activators

重新调整曲妥珠单抗的 Fab 结构域可产生强效的 HER2 激活剂

Justin M Scheer, Wendy Sandoval, J Michael Elliott, Lily Shao, Elizabeth Luis, Sock-Cheng Lewin-Koh, Gabriele Schaefer, Richard Vandlen