日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Tertiary lymphoid structures in the era of cancer therapy

癌症治疗时代的三级淋巴结构

Hernández-Verdin, Isaias; Dimberg, Anna; Thommen, Daniela S; Engblom, Camilla; Vanhersecke, Lucile; Silina, Karina; Bruno, Tullia C; Fridman, Wolf H; Nisticò, Paola; Sautès-Fridman, Catherine

Prediction of Mutations and Outcome in Gastrointestinal Stromal Tumors with Deep Learning: A Multicenter, Multinational Study

利用深度学习预测胃肠道间质瘤的突变和预后:一项多中心、多国研究

Bonetti, A; Le, V L; Carrero, Z I; Wolf, F; Gustav, M; Lam, S W; Vanhersecke, L; Sobczuk, P; Le Loarer, F; Lenarcik, M; Rutkowski, P; van Sabben, J M; Steeghs, N; van Boven, H; Machado, I; Bagué, S; Navarro, S; Medina-Ceballos, E; Agra, C; Giner, F; Tapia, G; Hernández-Gallego, A; Civantos Jubera, G; Cuatrecasas, M; Lopez-Prades, S; Perret, R E; Soubeyran, I; Khalifa, E; Blouin, L; Wardelmann, E; Meurgey, A; Collini, P; Voloshin, A; Yatabe, Y; Hirano, H; Gronchi, A; Nishida, T; Bouché, O; Emile, J F; Ngo, C; Hohenberger, P; Cotarelo, C; Jakob, J; Bovee, J V M G; Gelderblom, H; Szumera-Cieckiewicz, A; Jean-Denis, M; Bollard, J; Lassau, N; Lecesne, A; Blay, J Y; Italiano, A; Crombé, A; Coindre, J M; Kather, J N

Reshaping the tumor microenvironment of cold soft-tissue sarcomas with anti-angiogenics: a phase 2 trial of regorafenib combined with avelumab

利用抗血管生成药物重塑冷软组织肉瘤的肿瘤微环境:瑞戈非尼联合阿维鲁单抗的 II 期临床试验

Toulmonde, Maud; Guégan, Jean-Philippe; Spalato-Ceruso, Mariella; Valentin, Thibaud; Bahleda, Rastilav; Peyraud, Florent; Rey, Christophe; Kind, Michèle; Cantarel, Coralie; Bellera, Carine; Vanhersecke, Lucile; Bessede, Alban; Italiano, Antoine

Spatially resolved transcriptomics reveal the determinants of primary resistance to immunotherapy in NSCLC with mature tertiary lymphoid structures

空间分辨转录组学揭示了具有成熟三级淋巴结构的 NSCLC 对免疫治疗产生原发性耐药性的决定因素

Florent Peyraud, Jean-Philippe Guégan, Christophe Rey, Oren Lara, Ophélie Odin, Marie Del Castillo, Lucile Vanhersecke, Jean-Michel Coindre, Emma Clot, Maxime Brunet, Thomas Grellety, Angélique Tasseel, Sylvestre Le Moulec, Robert J Johnston, Alban Bessede, Antoine Italiano0

Prognostic prediction in soft-tissue sarcomas using deep learning and digital pathology of tumor and margin areas

利用深度学习和肿瘤及边缘区域的数字病理学对软组织肉瘤进行预后预测

Michot, Audrey; Le, Van-Linh; Coindre, Jean-Michel; Velasco, Valérie; Soussi, Malika; Mesli, Nouria; Italiano, Antoine; Toulmonde, Maud; Le Cesne, Axel; Bonvalot, Sylvie; Vanhersecke, Lucile; Honoré, Charles; Ngo, Carine; Le Loarer, François; Saut, Olivier; Crombé, Amandine

Predictive value of tumor microenvironment on pathologic response to neoadjuvant chemotherapy in patients with undifferentiated pleomorphic sarcomas

肿瘤微环境对未分化多形性肉瘤患者新辅助化疗病理反应的预测价值

Guegan, Jean Philippe; El Ghazzi, Nathan; Vibert, Julien; Rey, Christophe; Vanhersecke, Lucile; Coindre, Jean Michel; Toulmonde, Maud; Spalato Ceruso, Mariella; Peyraud, Florent; Bessede, Alban; Italiano, Antoine

Reshaping the tumor microenvironment of cold soft-tissue sarcomas with oncolytic viral therapy: a phase 2 trial of intratumoral JX-594 combined with avelumab and low-dose cyclophosphamide

利用溶瘤病毒疗法重塑冷软组织肉瘤的肿瘤微环境:一项瘤内注射 JX-594 联合阿维鲁单抗和低剂量环磷酰胺的 II 期临床试验

Toulmonde, Maud; Guegan, Jean-Philippe; Spalato-Ceruso, Mariella; Peyraud, Florent; Kind, Michèle; Vanhersecke, Lucile; Le Loarer, François; Perret, Raul; Cantarel, Coralie; Bellera, Carine; Bessede, Alban; Italiano, Antoine

Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1 + antiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics.

通过空间转录组学和血浆蛋白质组学鉴定与胃癌中抗PD-1/PD-L1+抗血管生成原发性耐药相关的微环境特征

Cousin Sophie, Guégan Jean-Philippe, Shitara Kohei, Palmieri Lola Jade, Metges Jean Philippe, Pernot Simon, Fukuoka Shota, Koyama Shohei, Nishikawa Hiroyoshi, Bellera Carine A, Adenis Antoine, Gomez-Roca Carlos A, Cassier Philippe Alexandre, Hollebecque Antoine, Cantarel Coralie, Kind Michèle, Soubeyran Isabelle, Vanhersecke Lucile, Bessede Alban, Italiano Antoine

Deciphering the correlation between metabolic activity through 18F-FDG-PET/CT and immune landscape in soft-tissue sarcomas: an insight from the NEOSARCOMICS study

通过 18F-FDG-PET/CT 解读软组织肉瘤代谢活性与免疫图谱之间的相关性:来自 NEOSARCOMICS 研究的启示

Crombé, Amandine; Bertolo, Frédéric; Vanhersecke, Lucile; Guegan, Jean-Philippe; Bessede, Alban; Perret, Raul; Le Loarer, François; Chaire, Vanessa; Coindre, Jean-Michel; Lucchesi, Carlo; Italiano, Antoine

Analysis of PD1, LAG3, TIGIT, and TIM3 expression in human lung adenocarcinoma reveals a 25-gene signature predicting immunotherapy response

对人肺腺癌中PD1、LAG3、TIGIT和TIM3表达的分析揭示了一个包含25个基因的特征谱,该特征谱可预测免疫治疗反应。

Guégan, Jean-Philippe; Peyraud, Florent; Dadone-Montaudie, Bérengère; Teyssonneau, Diego; Palmieri, Lola-Jade; Clot, Emma; Cousin, Sophie; Roubaud, Guilhem; Cabart, Mathilde; Leroy, Laura; Lebreton, Coriolan; Rey, Christophe; Lara, Oren; Odin, Ophélie; Brunet, Maxime; Vanhersecke, Lucile; Gruyters, Ezogelin Oflazoglu; Achour, Ikbel; Belcaid, Leila; Le Moulec, Sylvestre; Grellety, Thomas; Bessede, Alban; Italiano, Antoine