文献库，生知库 | 链接生命科学的每一步

Hernández-Verdin, Isaias; Dimberg, Anna; Thommen, Daniela S; Engblom, Camilla; Vanhersecke, Lucile; Silina, Karina; Bruno, Tullia C; Fridman, Wolf H; Nisticò, Paola; Sautès-Fridman, Catherine

肿瘤

肿瘤免疫

发表日期：2026

文献求助收藏

Adenosine A2B Receptor Promotes Tumor Progression and Metastases in Undifferentiated Pleomorphic Sarcoma

腺苷A2B受体促进未分化多形性肉瘤的肿瘤进展和转移

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-24-3934

Spalato Ceruso, Mariella; Guégan, Jean-Philippe; Bourdon, Aurélien; Chaire, Vanessa; Valverde Timana, Yanina; Giese, Alban; Rey, Christophe; Bessede, Alban; Perret, Raul; Vanhersecke, Lucile; Velasco, Valérie; Finetti, Pascal; Bertucci, François; Verbeke, Stéphanie; Italiano, Antoine

Reshaping the tumor microenvironment of cold soft-tissue sarcomas with anti-angiogenics: a phase 2 trial of regorafenib combined with avelumab

利用抗血管生成药物重塑冷软组织肉瘤的肿瘤微环境：瑞戈非尼联合阿维鲁单抗的 II 期临床试验

期刊:Signal Transduction and Targeted Therapy

影响因子:52.7

doi:10.1038/s41392-025-02278-9

Toulmonde, Maud; Guégan, Jean-Philippe; Spalato-Ceruso, Mariella; Valentin, Thibaud; Bahleda, Rastilav; Peyraud, Florent; Rey, Christophe; Kind, Michèle; Cantarel, Coralie; Bellera, Carine; Vanhersecke, Lucile; Bessede, Alban; Italiano, Antoine

Prognostic prediction in soft-tissue sarcomas using deep learning and digital pathology of tumor and margin areas

利用深度学习和肿瘤及边缘区域的数字病理学对软组织肉瘤进行预后预测

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-20804-1

Michot, Audrey; Le, Van-Linh; Coindre, Jean-Michel; Velasco, Valérie; Soussi, Malika; Mesli, Nouria; Italiano, Antoine; Toulmonde, Maud; Le Cesne, Axel; Bonvalot, Sylvie; Vanhersecke, Lucile; Honoré, Charles; Ngo, Carine; Le Loarer, François; Saut, Olivier; Crombé, Amandine

Predictive value of tumor microenvironment on pathologic response to neoadjuvant chemotherapy in patients with undifferentiated pleomorphic sarcomas

肿瘤微环境对未分化多形性肉瘤患者新辅助化疗病理反应的预测价值

期刊:Journal of Hematology & Oncology

影响因子:40.4

doi:10.1186/s13045-024-01614-w

Guegan, Jean Philippe; El Ghazzi, Nathan; Vibert, Julien; Rey, Christophe; Vanhersecke, Lucile; Coindre, Jean Michel; Toulmonde, Maud; Spalato Ceruso, Mariella; Peyraud, Florent; Bessede, Alban; Italiano, Antoine

Reshaping the tumor microenvironment of cold soft-tissue sarcomas with oncolytic viral therapy: a phase 2 trial of intratumoral JX-594 combined with avelumab and low-dose cyclophosphamide

利用溶瘤病毒疗法重塑冷软组织肉瘤的肿瘤微环境：一项瘤内注射 JX-594 联合阿维鲁单抗和低剂量环磷酰胺的 II 期临床试验

期刊:Molecular Cancer

影响因子:33.9

doi:10.1186/s12943-024-01946-8

Toulmonde, Maud; Guegan, Jean-Philippe; Spalato-Ceruso, Mariella; Peyraud, Florent; Kind, Michèle; Vanhersecke, Lucile; Le Loarer, François; Perret, Raul; Cantarel, Coralie; Bellera, Carine; Bessede, Alban; Italiano, Antoine

Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1â+âantiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics.

通过空间转录组学和血浆蛋白质组学鉴定与胃癌中抗PD-1/PD-L1+抗血管生成原发性耐药相关的微环境特征

期刊:Molecular Cancer

影响因子:33.9

doi:10.1186/s12943-024-02092-x

Cousin Sophie, GuÃ©gan Jean-Philippe, Shitara Kohei, Palmieri Lola Jade, Metges Jean Philippe, Pernot Simon, Fukuoka Shota, Koyama Shohei, Nishikawa Hiroyoshi, Bellera Carine A, Adenis Antoine, Gomez-Roca Carlos A, Cassier Philippe Alexandre, Hollebecque Antoine, Cantarel Coralie, Kind MichÃ¨le, Soubeyran Isabelle, Vanhersecke Lucile, Bessede Alban, Italiano Antoine

Deciphering the correlation between metabolic activity through 18F-FDG-PET/CT and immune landscape in soft-tissue sarcomas: an insight from the NEOSARCOMICS study

通过 18F-FDG-PET/CT 解读软组织肉瘤代谢活性与免疫图谱之间的相关性：来自 NEOSARCOMICS 研究的启示

期刊:Biomarker Research

影响因子:11.5

doi:10.1186/s40364-023-00552-y

Crombé, Amandine; Bertolo, Frédéric; Vanhersecke, Lucile; Guegan, Jean-Philippe; Bessede, Alban; Perret, Raul; Le Loarer, François; Chaire, Vanessa; Coindre, Jean-Michel; Lucchesi, Carlo; Italiano, Antoine

Analysis of PD1, LAG3, TIGIT, and TIM3 expression in human lung adenocarcinoma reveals a 25-gene signature predicting immunotherapy response

对人肺腺癌中PD1、LAG3、TIGIT和TIM3表达的分析揭示了一个包含25个基因的特征谱，该特征谱可预测免疫治疗反应。

期刊:Cell Reports Medicine

影响因子:10.6

doi:10.1016/j.xcrm.2024.101831

Guégan, Jean-Philippe; Peyraud, Florent; Dadone-Montaudie, Bérengère; Teyssonneau, Diego; Palmieri, Lola-Jade; Clot, Emma; Cousin, Sophie; Roubaud, Guilhem; Cabart, Mathilde; Leroy, Laura; Lebreton, Coriolan; Rey, Christophe; Lara, Oren; Odin, Ophélie; Brunet, Maxime; Vanhersecke, Lucile; Gruyters, Ezogelin Oflazoglu; Achour, Ikbel; Belcaid, Leila; Le Moulec, Sylvestre; Grellety, Thomas; Bessede, Alban; Italiano, Antoine

TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer

TROP2与晚期非小细胞肺癌患者对免疫检查点抑制剂的原发性耐药相关

期刊:Clinical Cancer Research

影响因子:10.2

doi:10.1158/1078-0432.CCR-23-2566

Bessede, Alban; Peyraud, Florent; Besse, Benjamin; Cousin, Sophie; Cabart, Mathilde; Chomy, François; Rey, Christophe; Lara, Oren; Odin, Ophélie; Nafia, Imane; Vanhersecke, Lucile; Barlesi, Fabrice; Guégan, Jean-Philippe; Italiano, Antoine

Tertiary lymphoid structures in the era of cancer therapy

癌症治疗时代的三级淋巴结构

Adenosine A2B Receptor Promotes Tumor Progression and Metastases in Undifferentiated Pleomorphic Sarcoma

腺苷A2B受体促进未分化多形性肉瘤的肿瘤进展和转移

Reshaping the tumor microenvironment of cold soft-tissue sarcomas with anti-angiogenics: a phase 2 trial of regorafenib combined with avelumab

利用抗血管生成药物重塑冷软组织肉瘤的肿瘤微环境：瑞戈非尼联合阿维鲁单抗的 II 期临床试验

Prognostic prediction in soft-tissue sarcomas using deep learning and digital pathology of tumor and margin areas

利用深度学习和肿瘤及边缘区域的数字病理学对软组织肉瘤进行预后预测

Predictive value of tumor microenvironment on pathologic response to neoadjuvant chemotherapy in patients with undifferentiated pleomorphic sarcomas

肿瘤微环境对未分化多形性肉瘤患者新辅助化疗病理反应的预测价值

Reshaping the tumor microenvironment of cold soft-tissue sarcomas with oncolytic viral therapy: a phase 2 trial of intratumoral JX-594 combined with avelumab and low-dose cyclophosphamide

利用溶瘤病毒疗法重塑冷软组织肉瘤的肿瘤微环境：一项瘤内注射 JX-594 联合阿维鲁单抗和低剂量环磷酰胺的 II 期临床试验

Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1â+âantiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics.

通过空间转录组学和血浆蛋白质组学鉴定与胃癌中抗PD-1/PD-L1+抗血管生成原发性耐药相关的微环境特征

Deciphering the correlation between metabolic activity through 18F-FDG-PET/CT and immune landscape in soft-tissue sarcomas: an insight from the NEOSARCOMICS study

通过 18F-FDG-PET/CT 解读软组织肉瘤代谢活性与免疫图谱之间的相关性：来自 NEOSARCOMICS 研究的启示

Analysis of PD1, LAG3, TIGIT, and TIM3 expression in human lung adenocarcinoma reveals a 25-gene signature predicting immunotherapy response

对人肺腺癌中PD1、LAG3、TIGIT和TIM3表达的分析揭示了一个包含25个基因的特征谱，该特征谱可预测免疫治疗反应。

TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer

TROP2与晚期非小细胞肺癌患者对免疫检查点抑制剂的原发性耐药相关

Tertiary lymphoid structures in the era of cancer therapy

癌症治疗时代的三级淋巴结构

Adenosine A2B Receptor Promotes Tumor Progression and Metastases in Undifferentiated Pleomorphic Sarcoma

腺苷A2B受体促进未分化多形性肉瘤的肿瘤进展和转移

Reshaping the tumor microenvironment of cold soft-tissue sarcomas with anti-angiogenics: a phase 2 trial of regorafenib combined with avelumab

利用抗血管生成药物重塑冷软组织肉瘤的肿瘤微环境：瑞戈非尼联合阿维鲁单抗的 II 期临床试验

Prognostic prediction in soft-tissue sarcomas using deep learning and digital pathology of tumor and margin areas

利用深度学习和肿瘤及边缘区域的数字病理学对软组织肉瘤进行预后预测

Predictive value of tumor microenvironment on pathologic response to neoadjuvant chemotherapy in patients with undifferentiated pleomorphic sarcomas

肿瘤微环境对未分化多形性肉瘤患者新辅助化疗病理反应的预测价值

Reshaping the tumor microenvironment of cold soft-tissue sarcomas with oncolytic viral therapy: a phase 2 trial of intratumoral JX-594 combined with avelumab and low-dose cyclophosphamide

利用溶瘤病毒疗法重塑冷软组织肉瘤的肿瘤微环境：一项瘤内注射 JX-594 联合阿维鲁单抗和低剂量环磷酰胺的 II 期临床试验

Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1â+âantiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics.

通过空间转录组学和血浆蛋白质组学鉴定与胃癌中抗PD-1/PD-L1+抗血管生成原发性耐药相关的微环境特征

Deciphering the correlation between metabolic activity through 18F-FDG-PET/CT and immune landscape in soft-tissue sarcomas: an insight from the NEOSARCOMICS study

通过 18F-FDG-PET/CT 解读软组织肉瘤代谢活性与免疫图谱之间的相关性：来自 NEOSARCOMICS 研究的启示

Analysis of PD1, LAG3, TIGIT, and TIM3 expression in human lung adenocarcinoma reveals a 25-gene signature predicting immunotherapy response

对人肺腺癌中PD1、LAG3、TIGIT和TIM3表达的分析揭示了一个包含25个基因的特征谱，该特征谱可预测免疫治疗反应。

TROP2 Is Associated with Primary Resistance to Immune Checkpoint Inhibition in Patients with Advanced Non-Small Cell Lung Cancer

TROP2与晚期非小细胞肺癌患者对免疫检查点抑制剂的原发性耐药相关

Identification of microenvironment features associated with primary resistance to anti-PD-1/PD-L1â+âantiangiogenesis in gastric cancer through spatial transcriptomics and plasma proteomics.