日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation

HIV-1 vif介导APOBEC3H二聚体近端亚基的泛素化,从而诱导其降解。

Katarzyna A Skorupka #,Kazuhiro Matsuoka #,Bakar Hassan,Rodolfo Ghirlando,Vanivilasini Balachandran,Ting-Hua Chen,Kylie J Walters,Celia A Schiffer,Matthias Wolf,Yasumasa Iwatani,Hiroshi Matsuo

Next generation APOBEC3 inhibitors: optimally designed for potency and nuclease stability

新一代APOBEC3抑制剂:针对效力和核酸酶稳定性进行了优化设计

Hedger, Adam K; Myint, Wazo; Lee, Jeong Min; Suchenski Loustaunau, Diego; Balachandran, Vanivilasini; Shaqra, Ala M; Kurt Yilmaz, Nese; Watts, Jonathan K; Matsuo, Hiroshi; Schiffer, Celia A

Next generation APOBEC3 inhibitors: Optimally designed for potency and nuclease stability

新一代APOBEC3抑制剂:针对效力和核酸酶稳定性进行了优化设计

Hedger, Adam K; Myint, Wazo; Lee, Jeong Min; Suchenski-Loustaunau, Diego; Balachandran, Vanivilasini; Shaqra, Ala M; Kurt-Yilmaz, Nese; Watts, Jonathan K; Matsuo, Hiroshi; Schiffer, Celia A

Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state

催化活性APOBEC3G与DNA寡核苷酸抑制剂结合的结构揭示了过渡态的四面体几何构型

Maiti, Atanu; Hedger, Adam K; Myint, Wazo; Balachandran, Vanivilasini; Watts, Jonathan K; Schiffer, Celia A; Matsuo, Hiroshi

Positioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance

将异染色质定位在核外围可抑制组蛋白周转以促进表观遗传

Sahana Holla, Jothy Dhakshnamoorthy, H Diego Folco, Vanivilasini Balachandran, Hua Xiao, Ling-Ling Sun, David Wheeler, Martin Zofall, Shiv I S Grewal

Crystal Structure of a Soluble APOBEC3G Variant Suggests ssDNA to Bind in a Channel that Extends between the Two Domains

可溶性 APOBEC3G 变体的晶体结构表明 ssDNA 结合在两个域之间延伸的通道中

Atanu Maiti, Wazo Myint, Krista A Delviks-Frankenberry, Shurong Hou, Tapan Kanai, Vanivilasini Balachandran, Christina Sierra Rodriguez, Rashmi Tripathi, Nese Kurt Yilmaz, Vinay K Pathak, Celia A Schiffer, Hiroshi Matsuo

A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing

保守的二聚体界面连接 ERH 和 YTH 家族蛋白以促进基因沉默

Guodong Xie, Tommy V Vo, Gobi Thillainadesan, Sahana Holla, Beibei Zhang, Yiyang Jiang, Mengqi Lv, Zheng Xu, Chongyuan Wang, Vanivilasini Balachandran, Yunyu Shi, Fudong Li, Shiv I S Grewal

CPF Recruitment to Non-canonical Transcription Termination Sites Triggers Heterochromatin Assembly and Gene Silencing

CPF 募集至非规范转录终止位点可引发异染色质组装和基因沉默

Tommy V Vo, Jothy Dhakshnamoorthy, Madeline Larkin, Martin Zofall, Gobi Thillainadesan, Vanivilasini Balachandran, Sahana Holla, David Wheeler, Shiv I S Grewal

Cohesin Impedes Heterochromatin Assembly in Fission Yeast Cells Lacking Pds5

在缺乏 Pds5 的裂殖酵母细胞中,黏连蛋白会阻碍异染色质的组装。

H Diego Folco ,Andrea McCue ,Vanivilasini Balachandran ,Shiv I S Grewal

Iron homeostasis regulates facultative heterochromatin assembly in adaptive genome control

铁稳态调节适应性基因组控制中的兼性异染色质组装

Pamela S Gallagher, Madeline Larkin, Gobi Thillainadesan, Jothy Dhakshnamoorthy, Vanivilasini Balachandran, Hua Xiao, Christopher Wellman, Raghunath Chatterjee, David Wheeler, Shiv I S Grewal