日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lipid nanoparticle GM-CSF replacement for autoimmune pulmonary alveolar proteinosis

脂质纳米颗粒GM-CSF替代疗法治疗自身免疫性肺泡蛋白沉积症

Lian, Liming; Jang, Bora; Huayamares, Sebastian G; Shakked, Avraham; Gentry, Kara; Zenhausern, Ryan; Radmand, Afsane; Schrader Echeverri, Elisa; Parihar, Vaunita C; Guerrero-Ferreira, Ricardo C; Calkins, Randi; Vanover, Daryll; Santangelo, Philip J; Kim, Hyejin; Dahlman, James E

Lumateperone monotherapy for major depressive episodes associated with bipolar disorder: efficacy and safety in a randomized placebo-controlled trial

鲁马特隆单药治疗双相情感障碍相关重度抑郁发作:一项随机安慰剂对照试验的疗效和安全性

Correll, Christoph U; Durgam, Suresh; Kozauer, Susan G; Lakkis, Hassan D; Chen, Changzheng; Vanover, Kimberly E; Mates, Sharon; Davis, Robert E

Sensitizing solid tumors to CAR-mediated cytotoxicity by lipid nanoparticle delivery of synthetic antigens

通过脂质纳米颗粒递送合成抗原增强实体瘤对CAR介导的细胞毒性的敏感性

Gamboa, Lena; Zamat, Ali H; Thiveaud, Chloé A; Lee, Hee Jun; Kulaksizoglu, Elif; Zha, Zizhen; Campbell, Noah S; Chan, Ching Shen; Fábrega, Sydney; Oliver, S Abbey; Su, Fang-Yi; Phuengkham, Hathaichanok; Vanover, Daryll; Peck, Hannah E; Sivakumar, Anirudh; Dahotre, Shreyas N; Harris, Adrian M; Santangelo, Philip J; Kwong, Gabriel A

Intravaginal delivery of mRNA-encoded antibodies with enhanced breadth and potency for SHIV/HIV protection

阴道内递送mRNA编码抗体,增强其广谱性和效力,用于SHIV/HIV保护

Jae Yeon Joo ,Peng Xiao ,Susan P John ,Daryll Vanover ,Hannah E Peck ,Loren E Sasser ,Deepanwita Bose ,Younghun Jung ,Jaehyeon Hwang ,Chiara Zurla ,Francois Villinger ,Philip J Santangelo

Nebulization of an mRNA-encoded monoclonal antibody for passive immunization of foals against Rhodococcus equi

利用雾化法将编码mRNA的单克隆抗体用于对幼驹进行被动免疫,以对抗马红球菌感染。

Rebecca M Legere ,Jeannine A Ott ,Cristina Poveda ,Daryll Vanover ,Karin E R Borba ,Jae Yeon Joo ,Cameron L Martin ,Bibiana P da Silveira ,Jocelyne M Bray ,Kerstin Landrock ,Gus A Wright ,J Chistensen Blazier ,Andrew E Hillhouse ,Ashley L Benham-Duret ,Brandon Mistretta ,Rafaela L Klein ,Sarah M Thompson ,Amelia R Woolums ,Michael F Criscitiello ,Luc R Berghman ,Angela I Bordin ,Philip J Santangelo ,Jeroen Pollet ,Noah D Cohen

ENX-101, a GABA(A) receptor α2,3,5-selective positive allosteric modulator, displays antiseizure effects in rodent seizure and epilepsy models.

ENX-101 是一种 GABA(A) 受体 α2,3,5 选择性正向变构调节剂,在啮齿动物癫痫模型中显示出抗癫痫作用

Serrats Jordi, Vadodaria Krishna C, Brubaker William, Barker-Haliski Melissa, White H Steve, Evrard Alexis, Roucard Corinne, Taylor Eve, Vanover Kimberly E, Cunningham Stephen, Sudarsan Vikram, Rogawski Michael A

Biomarker-Based Pharmacological Characterization of ENX-102, a Novel α2/3/5 Subtype-Selective GABAA Receptor Positive Allo-Steric Modulator: Translational Insights from Rodent and Human Studies

基于生物标志物的新型α2/3/5亚型选择性GABAA受体正向变构调节剂ENX-102的药理学表征:来自啮齿动物和人体研究的转化启示

Nettesheim, Pauline; Vadodaria, Krishna C; Vanover, Kimberly E; Borghans, Laura G J M; Arce, Estibaliz; Brubaker, William; Cunningham, Stephen; Parks, Stephanie; Serrats, Jordi; Sudarsan, Vikram; Taylor, Eve; Klaassen, Erica; Stuurman, Frederik E; Jacobs, Gabriel E

The SHFV nsp2 and nucleocapsid proteins recruit G3BP1 to sites of viral replication, but stress granules are not induced by the infection

SHFV nsp2 和核衣壳蛋白会将 G3BP1 募集到病毒复制位点,但感染不会诱导应激颗粒的产生。

Ayisha A Lavender ,Oreoluwa Solanke ,Hsin-Yao Tang ,Hannah E Peck ,Daryll Vanover ,Philip J Santangelo ,Margo A Brinton

Modulation of HER2 internalization enhances single-dose antibody-drug potency in HER2(+) gastric cancer.

调节 HER2 内化可增强单剂量抗体药物对 HER2(+) 胃癌的疗效

Zidel Abbey, Benton Alex, Brown Emma, Shmuel Shayla, Vanover Alex, Panikar Sandeep Surendra, Bose Ron, Park Haeseong, Davis Andrew A, Pereira Patrícia M R

MIB guides: [89Zr]Zr-DFO-trastuzumab and [64Cu]Cu-NOTA-Trastuzumab for Preclinical Cancer Imaging

MIB 指南:[89Zr]Zr-DFO-曲妥珠单抗和[64Cu]Cu-NOTA-曲妥珠单抗用于临床前癌症成像

Cristina Simó ,Alexander C Vanover ,E Carmen Azevedo ,Patrícia M R Pereira