日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Revealing the catalytic mechanism of the Fe(II)/2-oxoglutarate-dependent human epigenetic modifying enzyme ALKBH5

揭示Fe(II)/2-氧戊二酸依赖性人类表观遗传修饰酶ALKBH5的催化机制

Cherilakkudy, Fathima Hameed; Thomas, Midhun George; Varghese, Ann; Waheed, Sodiq O; Krishnan, Anandhu; Venditti, Vincenzo; Schofield, Christopher J; Li, Deyu; Christov, Christo Z; Karabencheva-Christova, Tatyana G

Catalytic Mechanism of the Bacterial Non-Heme Fe(II) and 2-Oxoglutarate Dependent Enzyme AlkB with Single-Stranded DNA Containing Complex Guanine Adducts

细菌非血红素Fe(II)和2-酮戊二酸依赖性酶AlkB与含复杂鸟嘌呤加合物的单链DNA的催化机制

Melayikandy, Sreerag; Krishnan, Anandhu; Varghese, Ann; Jaber Sathik Rifayee, Simahudeen Bathir; Waheed, Sodiq O; Ramanan, Rajeev; Li, Deyu; Christov, Christo Z; Karabencheva-Christova, Tatyana G

Analysis of Structures of SARS-CoV-2 Papain-like Protease Bound with Ligands Unveils Structural Features for Inhibiting the Enzyme

对SARS-CoV-2木瓜蛋白酶样蛋白酶与配体结合的结构分析揭示了抑制该酶的结构特征

Varghese, Ann; Liu, Jie; Liu, Bailang; Guo, Wenjing; Dong, Fan; Patterson, Tucker A; Hong, Huixiao

Integrating Molecular Dynamics, Molecular Docking, and Machine Learning for Predicting SARS-CoV-2 Papain-like Protease Binders

整合分子动力学、分子对接和机器学习技术预测SARS-CoV-2木瓜蛋白酶样蛋白酶结合物

Varghese, Ann; Liu, Jie; Patterson, Tucker A; Hong, Huixiao

Intrinsic and extrinsic feedback generate similar propulsion but distinct biomechanical strategies during split-belt walking

在分带行走过程中,内在反馈和外在反馈产生的推进力相似,但生物力学策略却截然不同。

Bin Shuwayyi, Hamad K; Reed, William R; Lin, Chen; Hill, Jonathan D; Varghese, Ann M; Liang, Ya-Yu; Hurt, Christopher P

Unusual catalytic strategy by non-heme Fe(ii)/2-oxoglutarate-dependent aspartyl hydroxylase AspH

非血红素 Fe(II)/2-氧戊二酸依赖性天冬氨酰羟化酶 AspH 的不寻常催化策略

Krishnan, Anandhu; Waheed, Sodiq O; Varghese, Ann; Cherilakkudy, Fathima Hameed; Schofield, Christopher J; Karabencheva-Christova, Tatyana G

Decoding the κ Opioid Receptor (KOR): Advancements in Structural Understanding and Implications for Opioid Analgesic Development.

解码α阿片受体(KOR):结构理解的进展及其对阿片类镇痛药开发的影响

Li Zoe, Huang Ruili, Xia Menghang, Chang Nancy, Guo Wenjing, Liu Jie, Dong Fan, Liu Bailang, Varghese Ann, Aslam Aasma, Patterson Tucker A, Hong Huixiao

Novel Insights into the Catalytic Mechanism of Collagenolysis by Zn(II)-Dependent Matrix Metalloproteinase-1

锌(II)依赖性基质金属蛋白酶-1催化胶原蛋白水解机制的新见解

Gorantla, Koteswara Rao; Krishnan, Anandhu; Waheed, Sodiq O; Varghese, Ann; DiCastri, Isabella; LaRouche, Ciara; Paik, Meredith; Fields, Gregg B; Karabencheva-Christova, Tatyana G

Revealing the Catalytic Strategy of FTO

揭示FTO的催化策略

Varghese, Ann; Waheed, Sodiq O; Chaturvedi, Shobhit S; DiCastri, Isabella; LaRouche, Ciara; Kaski, Brendan; Lehnert, Nicolai; Li, Deyu; Christov, Christo Z; Karabencheva-Christova, Tatyana G

Mechanism of the Early Catalytic Events in the Collagenolysis by Matrix Metalloproteinase-1

基质金属蛋白酶-1介导的胶原蛋白水解早期催化事件机制

Waheed, Sodiq O; Varghese, Ann; DiCastri, Isabella; Kaski, Brenden; LaRouche, Ciara; Fields, Gregg B; Karabencheva-Christova, Tatyana G