日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting RAD51-BRCA2 Interaction to Enhance Synthetic Lethality with Olaparib in Pancreatic Cancer: Development of a Novel Phenyl Furan-Quinoline-Carboxylic Acid Series

靶向 RAD51-BRCA2 相互作用以增强奥拉帕尼在胰腺癌中的合成致死性：新型苯基呋喃-喹啉-羧酸系列化合物的开发

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.5c00711
Ferrandi, Giovanni; Bagnolini, Greta; Poppi, Laura; Masi, Mirco; Previtali, Viola; Andonaia, Angela; Varignani, Giulia; Veronesi, Marina; De Franco, Francesca; Falchi, Federico; Di Stefano, Giuseppina; Girotto, Stefania; Roberti, Marinella; Cavalli, Andrea
肿瘤
肿瘤免疫
BRCA2
RAD51
胰腺癌
发表日期：2026
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Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality

针对 RAD51-BRCA2 相互作用的计算机设计适体可损害同源重组并诱导合成致死性

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66694-9
Milordini, Giulia; Zacco, Elsa; Masi, Mirco; Armaos, Alexandros; Di Palma, Francesco; Oneto, Michele; Gilodi, Martina; Rupert, Jakob; Broglia, Laura; Varignani, Giulia; Scotto, Marco; Marotta, Roberto; Girotto, Stefania; Cavalli, Andrea; Tartaglia, Gian Gaetano
BRCA2
RAD51
发表日期：2025
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Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity

通过对映体差异活性研究胰腺癌中的合成致死性和PARP抑制剂耐药性

期刊:Cell Death Discovery
影响因子:6.1
doi:10.1038/s41420-025-02382-3
Mirco Masi # ，Laura Poppi # ，Viola Previtali # ，Shannon R Nelson ，Kieran Wynne ，Giulia Varignani ，Federico Falchi ，Marina Veronesi ，Ennio Albanesi ，Daniele Tedesco ，Francesca De Franco ，Andrea Ciamarone ，Samuel H Myers ，Jose Antonio Ortega ，Greta Bagnolini ，Giovanni Ferrandi ，Fulvia Farabegoli ，Nicola Tirelli ，Giuseppina Di Stefano ，Giorgio Oliviero ，Naomi Walsh ，Marinella Roberti ，Stefania Girotto ，Andrea Cavalli
肿瘤
胰腺癌
肿瘤免疫
发表日期：2025
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An integrative structural study of the human full-length RAD52 at 2.2 Å resolution

2.2 Å 分辨率的人类全长 RAD52 综合结构研究

期刊:Communications Biology
影响因子:5.2
doi:10.1038/s42003-024-06644-1
Beatrice Balboni #, Roberto Marotta #, Francesco Rinaldi, Giulia Milordini, Giulia Varignani, Stefania Girotto, Andrea Cavalli
RAD52
发表日期：2024
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