日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Precision-guided antimicrobial peptide as a targeted modulator of human microbial ecology

精准导向的抗菌肽作为人类微生物生态的靶向调节剂

Guo, Lihong; McLean, Jeffrey S; Yang, Youngik; Eckert, Randal; Kaplan, Christopher W; Kyme, Pierre; Sheikh, Omid; Varnum, Brian; Lux, Renate; Shi, Wenyuan; He, Xuesong

In brain, Axl recruits Grb2 and the p85 regulatory subunit of PI3 kinase; in vitro mutagenesis defines the requisite binding sites for downstream Akt activation

在大脑中,Axl 募集 Grb2 和 PI3 激酶的 p85 调节亚基;体外诱变实验确定了下游 Akt 激活所需的结合位点。

Weinger, Jason G; Gohari, Pouyan; Yan, Ying; Backer, Jonathan M; Varnum, Brian; Shafit-Zagardo, Bridget

Regulation of microglial phagocytosis and inflammatory gene expression by Gas6 acting on the Axl/Mer family of tyrosine kinases.

Gas6 通过作用于 Axl/Mer 家族酪氨酸激酶来调节小胶质细胞的吞噬作用和炎症基因表达

Grommes Christian, Lee C Y Daniel, Wilkinson Brandy L, Jiang Qingguang, Koenigsknecht-Talboo Jessica L, Varnum Brian, Landreth Gary E

Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis

Gas6/Axl信号通路激活磷脂酰肌醇3-激酶/Akt1存活通路,从而保护少突胶质细胞免受肿瘤坏死因子α诱导的细胞凋亡。

Shankar, Sai Latha; O'Guin, Kathleen; Kim, Mimi; Varnum, Brian; Lemke, Greg; Brosnan, Celia F; Shafit-Zagardo, Bridget

The growth arrest-specific gene product Gas6 promotes the survival of human oligodendrocytes via a phosphatidylinositol 3-kinase-dependent pathway

生长停滞特异性基因产物Gas6通过磷脂酰肌醇3-激酶依赖性通路促进人少突胶质细胞的存活。

Shankar, Sai Latha; O'Guin, Kathleen; Cammer, Michael; McMorris, F Arthur; Stitt, Trevor N; Basch, Ross S; Varnum, Brian; Shafit-Zagardo, Bridget