日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The Parkinson's Disease Drug Tolcapone and Analogues are Potent Glycomimetic Lectin Inhibitors of Pseudomonas aeruginosa LecA

帕金森病药物托卡朋及其类似物是铜绿假单胞菌LecA的强效糖模拟凝集素抑制剂。

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202508864
Leusmann, Steffen; Siebs, Eike; Kuhaudomlarp, Sakonwan; Varrot, Annabelle; Imberty, Anne; Kuhn, Bernd; Lerner, Christian; Grether, Uwe; Titz, Alexander
帕金森
神经科学
发表日期：2025
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Toward Dual-Target Glycomimetics against Two Bacterial Lectins to Fight Pseudomonas aeruginosa-Burkholderia cenocepacia Infections: A Biophysical Study

针对两种细菌凝集素的双靶点糖模拟物对抗铜绿假单胞菌-洋葱伯克霍尔德菌感染：一项生物物理学研究

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00405
Antonini, Giulia; Fares, Mario; Hauck, Dirk; Mała, Patrycja; Gillon, Emilie; Belvisi, Laura; Bernardi, Anna; Titz, Alexander; Varrot, Annabelle; Mazzotta, Sarah
炎症/感染
微生物学
发表日期：2025
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Multivalent Fucosides Targeting β-Propeller Lectins from Lung Pathogens with Promising Anti-Adhesive Properties

具有抗粘附特性的多价岩藻糖苷靶向肺部病原体的β-螺旋桨凝集素

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.2c00708
Duca, Margherita; Haksar, Diksha; van Neer, Jacq; Thies-Weesie, Dominique M E; Martínez-Alarcón, Dania; de Cock, Hans; Varrot, Annabelle; Pieters, Roland J
微生物学
发表日期：2022
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Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity

灰盖鬼伞子实体中一种新型岩藻糖苷结合凝集素的结构-功能关系及其对线虫的毒性活性

期刊:Glycobiology
影响因子:3.3
doi:10.1093/glycob/cwac020
Bleuler-Martinez, Silvia; Varrot, Annabelle; Olieric, Vincent; Schubert, Mario; Vogt, Eva; Fetz, Céline; Wohlschlager, Therese; Plaza, David Fernando; Wälti, Martin; Duport, Yannick; Capitani, Guido; Aebi, Markus; Künzler, Markus
毒理研究
发表日期：2022
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Non-Carbohydrate Glycomimetics as Inhibitors of Calcium(II)-Binding Lectins

非碳水化合物糖模拟物作为钙(II)结合凝集素的抑制剂

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202013217
Kuhaudomlarp, Sakonwan; Siebs, Eike; Shanina, Elena; Topin, Jérémie; Joachim, Ines; da Silva Figueiredo Celestino Gomes, Priscila; Varrot, Annabelle; Rognan, Didier; Rademacher, Christoph; Imberty, Anne; Titz, Alexander
发表日期：2021
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Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors

抗铜绿假单胞菌生物膜剂：C-糖苷类LecB抑制剂的构效关系研究

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.9b01120
Sommer, Roman; Rox, Katharina; Wagner, Stefanie; Hauck, Dirk; Henrikus, Sarah S; Newsad, Shelby; Arnold, Tatjana; Ryckmans, Thomas; Brönstrup, Mark; Imberty, Anne; Varrot, Annabelle; Hartmann, Rolf W; Titz, Alexander
微生物学
发表日期：2019
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Effect of Noncanonical Amino Acids on Protein-Carbohydrate Interactions: Structure, Dynamics, and Carbohydrate Affinity of a Lectin Engineered with Fluorinated Tryptophan Analogs

非天然氨基酸对蛋白质-碳水化合物相互作用的影响：用氟化色氨酸类似物改造的凝集素的结构、动力学和碳水化合物亲和力

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.8b00377
Tobola, Felix; Lelimousin, Mickael; Varrot, Annabelle; Gillon, Emilie; Darnhofer, Barbara; Blixt, Ola; Birner-Gruenberger, Ruth; Imberty, Anne; Wiltschi, Birgit
发表日期：2018
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Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging

共价凝集素抑制及其在细菌生物膜成像中的应用

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.201709368
Wagner, Stefanie; Hauck, Dirk; Hoffmann, Michael; Sommer, Roman; Joachim, Ines; Müller, Rolf; Imberty, Anne; Varrot, Annabelle; Titz, Alexander
微生物学
发表日期：2017
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The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery

毒力因子LecB在临床分离株中存在差异：对配体结合和药物发现的影响

期刊:Chemical Science
影响因子:7.4
doi:10.1039/c6sc00696e
Sommer, Roman; Wagner, Stefanie; Varrot, Annabelle; Nycholat, Corwin M; Khaledi, Ariane; Häussler, Susanne; Paulson, James C; Imberty, Anne; Titz, Alexander
微生物学
发表日期：2016
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Genomic Rearrangements and Functional Diversification of lecA and lecB Lectin-Coding Regions Impacting the Efficacy of Glycomimetics Directed against Pseudomonas aeruginosa

lecA 和 lecB 凝集素编码区的基因组重排和功能多样化影响针对铜绿假单胞菌的糖模拟物的疗效

期刊:Frontiers in Microbiology
影响因子:4.5
doi:10.3389/fmicb.2016.00811
Boukerb, Amine M; Decor, Aude; Ribun, Sébastien; Tabaroni, Rachel; Rousset, Audric; Commin, Loris; Buff, Samuel; Doléans-Jordheim, Anne; Vidal, Sébastien; Varrot, Annabelle; Imberty, Anne; Cournoyer, Benoit
发表日期：2016
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