日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dual targeting of iNOS and Src tyrosine kinase as a superior therapeutic strategy against soman-induced long-term neurotoxicity: multimodal biomarker, imaging, and neurobehavioral outcome analyses.

以 iNOS 和 Src 酪氨酸激酶为双重靶点,对抗梭曼诱导的长期神经毒性,是一种更优的治疗策略:多模态生物标志物、成像和神经行为结果分析。

Massey Nyzil, Vasanthi Suraj S, Meyer Christina, Rao Nikhil S, Thedens Daniel R, Wang Chong, Kannurpatti Sridhar, Thippeswamy Thimmasettappa

Mitigating organophosphate nerve agent, soman (GD), induced long-term neurotoxicity: Saracatinib, a Src Tyrosine Kinase inhibitor, as a potential countermeasure.

减轻有机磷神经毒剂索曼(GD)引起的长期神经毒性:Src酪氨酸激酶抑制剂萨拉卡替尼作为一种潜在的应对措施

Massey Nyzil, Vasanthi Suraj S, Holtkamp Claire, Meyer Christina, Rao Nikhil S, Gimenez-Lirola Luis G, Wang Chong, Im Hyunmook, Bevoor Avinash S, Kannurpatti Sridhar, Thippeswamy Thimmasettappa

Proinflammatory cytokines, oxidative stress, and organ function as biomarkers of soman (GD) chronic neurotoxicity.

促炎细胞因子、氧化应激和器官功能作为梭曼(GD)慢性神经毒性的生物标志物

Massey Nyzil, Vasanthi Suraj S, Gimenez-Lirola Luis G, Tyler Harm, Thippeswamy Thimmasettappa

Mitigating Organophosphate Nerve Agent, Soman (GD)-Induced Long-Term Neurotoxicity: Saracatinib, a Src Tyrosine Kinase Inhibitor, as a Potential Countermeasure.

缓解有机磷神经毒剂索曼(GD)引起的长期神经毒性:Src酪氨酸激酶抑制剂萨拉卡替尼作为一种潜在的应对措施

Massey Nyzil, Vasanthi Suraj S, Holtkamp Claire, Meyer Christina, Rao Nikhil S, Gimenez-Lirola Luis G, Wang Chong, Im Hyunmook, Bevoor Avinash S, Kannurpatti Sridhar, Thippeswamy Thimmasettappa

Inhibiting Inducible Nitric Oxide Synthase with 1400W Reduces Soman (GD)-Induced Ferroptosis in Long-Term Epilepsy-Associated Neuropathology: Structural and Functional Magnetic Resonance Imaging Correlations with Neurobehavior and Brain Pathology

使用 1400W 抑制诱导型一氧化氮合酶可减少长期癫痫相关神经病理中索曼 (GD) 诱导的铁死亡:结构和功能磁共振成像与神经行为和脑病理的相关性

Putra, Marson; Vasanthi, Suraj S; Rao, Nikhil S; Meyer, Christina; Van Otterloo, Madison; Thangi, Lal; Thedens, Daniel R; Kannurpatti, Sridhar S; Thippeswamy, Thimmasettappa

Peripheral and central effects of NADPH oxidase inhibitor, mitoapocynin, in a rat model of diisopropylfluorophosphate (DFP) toxicity

NADPH氧化酶抑制剂线粒体阿波西宁在二异丙基氟磷酸酯(DFP)中毒大鼠模型中的外周和中枢效应

Meyer, Christina; Rao, Nikhil S; Vasanthi, Suraj S; Pereira, Beatriz; Gage, Meghan; Putra, Marson; Holtkamp, Claire; Huss, Joselyn; Thippeswamy, Thimmasettappa

Sex-based structural and functional MRI outcomes in the rat brain after soman (GD) exposure-induced status epilepticus

大鼠脑内基于性别的结构和功能磁共振成像结果在索曼(GD)暴露诱发癫痫持续状态后的变化

Gage, Meghan; Vasanthi, Suraj S; Meyer, Christina M; Rao, Nikhil S; Thedens, Daniel R; Kannurpatti, Sridhar S; Thippeswamy, Thimmasettappa

Disease-Modifying Effects of a Glial-targeted Inducible Nitric Oxide Synthase Inhibitor (1400W) in Mixed-sex Cohorts of a Rat Soman (GD) Model of Epilepsy

神经胶质细胞靶向诱导型一氧化氮合酶抑制剂 (1400W) 在混合性别大鼠索曼 (GD) 癫痫模型中的疾病修饰作用

Vasanthi, Suraj S; Rao, Nikhil S; Samidurai, Manikandan; Massey, Nyzil; Meyer, Christina; Gage, Meghan; Kharate, Mihir; Almanza, Aida; Wachter, Logan; Mafuta, Candide; Trevino, Lily; Carlo, Adriana M; Bryant, Elijah; Corson, Brooke E; Wohlgemuth, Morgan; Ostrander, Morgan; Wang, Chong; Thippeswamy, Thimmasettappa

DFP-Induced Status Epilepticus Severity in Mixed-Sex Cohorts of Adult Rats Housed in the Same Room: Behavioral and EEG Comparisons

同一房间内饲养的雌雄成年大鼠中DFP诱发的癫痫持续状态严重程度:行为学和脑电图比较

Rao, Nikhil S; Meyer, Christina; Vasanthi, Suraj S; Massey, Nyzil; Samidurai, Manikandan; Gage, Meghan; Putra, Marson; Almanza, Aida N; Wachter, Logan; Thippeswamy, Thimmasettappa