日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

"Specificity Determinants" Improve Therapeutic Indices of Two Antimicrobial Peptides Piscidin 1 and Dermaseptin S4 Against the Gram-negative Pathogens Acinetobacter baumannii and Pseudomonas aeruginosa

“特异性决定因素”提高了两种抗菌肽Piscidin 1和Dermaseptin S4对革兰氏阴性致病菌鲍曼不动杆菌和铜绿假单胞菌的治疗指数。

Jiang, Ziqing; Vasil, Adriana I; Vasil, Michael L; Hodges, Robert S

Iron-regulated expression of alginate production, mucoid phenotype, and biofilm formation by Pseudomonas aeruginosa

铁调控铜绿假单胞菌的藻酸盐产生、粘液表型和生物膜形成

Wiens, Jacinta R; Vasil, Adriana I; Schurr, Michael J; Vasil, Michael L

The complex interplay of iron, biofilm formation, and mucoidy affecting antimicrobial resistance of Pseudomonas aeruginosa

铁、生物膜形成和黏液性之间的复杂相互作用影响铜绿假单胞菌的抗菌素耐药性

Oglesby-Sherrouse, Amanda G; Djapgne, Louise; Nguyen, Angela T; Vasil, Adriana I; Vasil, Michael L

Hemolytic phospholipase C inhibition protects lung function during Pseudomonas aeruginosa infection

溶血性磷脂酶C抑制剂可保护铜绿假单胞菌感染期间的肺功能

Wargo, Matthew J; Gross, Maegan J; Rajamani, Sathish; Allard, Jenna L; Lundblad, Lennart K A; Allen, Gilman B; Vasil, Michael L; Leclair, Laurie W; Hogan, Deborah A

Molecular Investigations of PenA-mediated β-lactam Resistance in Burkholderia pseudomallei.

伯克霍尔德氏菌中 PenA 介导的 β-内酰胺类抗生素耐药性的分子研究

Rholl Drew A, Papp-Wallace Krisztina M, Tomaras Andrew P, Vasil Michael L, Bonomo Robert A, Schweizer Herbert P

Rational design of α-helical antimicrobial peptides to target Gram-negative pathogens, Acinetobacter baumannii and Pseudomonas aeruginosa: utilization of charge, 'specificity determinants,' total hydrophobicity, hydrophobe type and location as design parameters to improve the therapeutic ratio

合理设计靶向革兰氏阴性病原体鲍曼不动杆菌和铜绿假单胞菌的α螺旋抗菌肽:利用电荷、“特异性决定因素”、总疏水性、疏水基团类型和位置作为设计参数以提高治疗比率

Jiang, Ziqing; Vasil, Adriana I; Gera, Lajos; Vasil, Michael L; Hodges, Robert S

End-products diacylglycerol and ceramide modulate membrane fusion induced by a phospholipase C/sphingomyelinase from Pseudomonas aeruginosa

终产物二酰甘油和神经酰胺调节铜绿假单胞菌磷脂酶C/鞘磷脂酶诱导的膜融合

Ibarguren, Maitane; Bomans, Paul H H; Frederik, Peter M; Stonehouse, Martin; Vasil, Adriana I; Vasil, Michael L; Alonso, Alicia; Goñi, Félix M

A complex extracellular sphingomyelinase of Pseudomonas aeruginosa inhibits angiogenesis by selective cytotoxicity to endothelial cells

铜绿假单胞菌的复杂胞外鞘磷脂酶通过对内皮细胞的选择性细胞毒性抑制血管生成。

Vasil, Michael L; Stonehouse, Martin J; Vasil, Adriana I; Wadsworth, Sandra J; Goldfine, Howard; Bolcome, Robert E 3rd; Chan, Joanne

Mycobacterium tuberculosis Rv3802c encodes a phospholipase/thioesterase and is inhibited by the antimycobacterial agent tetrahydrolipstatin.

结核分枝杆菌 Rv3802c 编码一种磷脂酶/硫酯酶,可被抗分枝杆菌药物四氢脂抑素抑制

Parker Sarah K, Barkley Robert M, Rino John G, Vasil Michael L

Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides

净电荷和带正电荷残基数量对两亲性α螺旋阳离子抗菌肽生物活性的影响

Jiang, Ziqing; Vasil, Adriana I; Hale, John D; Hancock, Robert E W; Vasil, Michael L; Hodges, Robert S