mTOR inhibition triggers mitochondrial fragmentation in cardiomyocytes through proteosome-dependent prohibitin degradation and OPA-1 cleavage.
mTOR 抑制通过蛋白酶体依赖的prohibitin降解和 OPA-1 裂解引发心肌细胞线粒体断裂
期刊:Cell Communication and Signaling
影响因子:8.9
doi:10.1186/s12964-025-02240-w
Verdejo Hugo E, Parra Valentina, Del Campo Andrea, Vasquez-Trincado Cesar, Gatica Damian, Lopez-Crisosto Camila, Kuzmicic Jovan, Venegas-Zamora Leslye, Zuñiga-Cuevas Ursula, Troncoso Mayarling F, Troncoso Rodrigo, Rothermel Beverly A, Chiong Mario, Abel E Dale, Lavandero Sergio
