Differential Apaf-1 levels allow cytochrome c to induce apoptosis in brain tumors but not in normal neural tissues.
Apaf-1 水平的差异使得细胞色素 c 能够诱导脑肿瘤细胞凋亡,但不能诱导正常神经组织细胞凋亡
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.0709101105
Johnson Carrie E, Huang Yolanda Y, Parrish Amanda B, Smith Michelle I, Vaughn Allyson E, Zhang Qian, Wright Kevin M, Van Dyke Terry, Wechsler-Reya Robert J, Kornbluth Sally, Deshmukh Mohanish