日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Virotherapy combined with anti-PD-1 transiently reshapes the tumor immune environment and induces anti-tumor immunity in a preclinical PDAC model

病毒疗法联合抗PD-1抗体可暂时性地重塑肿瘤免疫微环境,并在临床前PDAC模型中诱导抗肿瘤免疫。

Veinalde, Rūta; Pidelaserra-Martí, Gemma; Moulin, Coline; Tan, Chin Leng; Schäfer, Theresa E; Kang, Na; Ball, Claudia R; Leichsenring, Jonas; Stenzinger, Albrecht; Kaderali, Lars; Jäger, Dirk; Ungerechts, Guy; Engeland, Christine E

Oncolytic measles vaccines encoding PD-1 and PD-L1 checkpoint blocking antibodies to increase tumor-specific T cell memory

编码PD-1和PD-L1检查点阻断抗体的溶瘤性麻疹疫苗可增强肿瘤特异性T细胞记忆

Rūta Veinalde,Gemma Pidelaserra-Martí,Coline Moulin,Lara M Jeworowski,Linda Küther,Christian J Buchholz,Dirk Jäger,Guy Ungerechts,Christine E Engeland

Immunological Effects and Viral Gene Expression Determine the Efficacy of Oncolytic Measles Vaccines Encoding IL-12 or IL-15 Agonists

免疫学效应和病毒基因表达决定了编码 IL-12 或 IL-15 激动剂的溶瘤麻疹疫苗的有效性

Paul S Backhaus, Rūta Veinalde, Laura Hartmann, Jessica E Dunder, Lara M Jeworowski, Jessica Albert, Birgit Hoyler, Tanja Poth, Dirk Jäger, Guy Ungerechts, Christine E Engeland9

Targeted BiTE Expression by an Oncolytic Vector Augments Therapeutic Efficacy Against Solid Tumors

溶瘤载体靶向表达 BiTE 可增强实体肿瘤的治疗效果

Tobias Speck, Johannes P W Heidbuechel, Rūta Veinalde, Dirk Jaeger, Christof von Kalle, Claudia R Ball, Guy Ungerechts, Christine E Engeland

Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activation

编码白细胞介素-12 的溶瘤麻疹病毒通过 T 细胞活化介导强大的抗肿瘤作用

Rūta Veinalde, Christian Grossardt, Laura Hartmann, Marie-Claude Bourgeois-Daigneault, John C Bell, Dirk Jäger, Christof von Kalle, Guy Ungerechts, Christine E Engeland