日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials.

氧化磷酸化复合物 I 抑制剂在晚期实体瘤和急性髓系白血病中的应用：I 期试验

期刊:Nature Medicine
影响因子:50
doi:10.1038/s41591-022-02103-8
Yap Timothy A, Daver Naval, Mahendra Mikhila, Zhang Jixiang, Kamiya-Matsuoka Carlos, Meric-Bernstam Funda, Kantarjian Hagop M, Ravandi Farhad, Collins Meghan E, Francesco Maria Emilia Di, Dumbrava Ecaterina E, Fu Siqing, Gao Sisi, Gay Jason P, Gera Sonal, Han Jing, Hong David S, Jabbour Elias J, Ju Zhenlin, Karp Daniel D, Lodi Alessia, Molina Jennifer R, Baran Natalia, Naing Aung, Ohanian Maro, Pant Shubham, Pemmaraju Naveen, Bose Prithviraj, Piha-Paul Sarina A, Rodon Jordi, Salguero Carolina, Sasaki Koji, Singh Anand K, Subbiah Vivek, Tsimberidou Apostolia M, Xu Quanyun A, Yilmaz Musa, Zhang Qi, Li Yuan, Bristow Christopher A, Bhattacharjee Meenakshi B, Tiziani Stefano, Heffernan Timothy P, Vellano Christopher P, Jones Philip, Heijnen Cobi J, Kavelaars Annemieke, Marszalek Joseph R, Konopleva Marina
肿瘤
白血病
磷酸化
发表日期：2023
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Subtype and Site Specific-Induced Metabolic Vulnerabilities in Prostate Cancer

前列腺癌亚型和部位特异性诱导的代谢脆弱性

期刊:Molecular Cancer Research
影响因子:4.7
doi:10.1158/1541-7786.MCR-22-0250
Mossa, Federica; Robesti, Daniele; Sumankalai, Ramachandran; Corey, Eva; Titus, Mark; Kang, Yuqi; Zhang, Jianhua; Briganti, Alberto; Montorsi, Francesco; Vellano, Christopher P; Marszalek, Joseph R; Frigo, Daniel E; Logothetis, Christopher J; Gujral, Taranjit S; Dondossola, Eleonora
肿瘤
前列腺癌
肿瘤免疫
代谢
发表日期：2023
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Phase Ib Dose Expansion and Translational Analyses of Olaparib in Combination with Capivasertib in Recurrent Endometrial, Triple-Negative Breast, and Ovarian Cancer

奥拉帕尼联合卡帕替尼治疗复发性子宫内膜癌、三阴性乳腺癌和卵巢癌的Ib期剂量扩展和转化分析

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-21-1656
Westin, Shannon N; Labrie, Marilyne; Litton, Jennifer K; Blucher, Aurora; Fang, Yong; Vellano, Christopher P; Marszalek, Joseph R; Feng, Ningping; Ma, XiaoYan; Creason, Allison; Fellman, Bryan; Yuan, Ying; Lee, Sanghoon; Kim, Tae-Beom; Liu, Jinsong; Chelariu-Raicu, Anca; Chen, Tsun Hsuan; Kabil, Nashwa; Soliman, Pamela T; Frumovitz, Michael; Schmeler, Katheleen M; Jazaeri, Amir; Lu, Karen H; Murthy, Rashmi; Meyer, Larissa A; Sun, Charlotte C; Sood, Anil K; Coleman, Robert L; Mills, Gordon B
肿瘤
子宫内膜癌
肿瘤免疫
乳腺癌
卵巢癌
发表日期：2021
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Development and characterization of prototypes for in vitro and in vivo mouse models of ibrutinib-resistant CLL

开发和表征用于体外和体内小鼠模型（针对伊布替尼耐药性慢性淋巴细胞白血病）的原型。

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2020003821
Aslan, Burcu; Kismali, Gorkem; Chen, Lisa S; Iles, LaKesla R; Mahendra, Mikhila; Peoples, Michael; Gagea, Mihai; Fowlkes, Natalie W; Zheng, Xiaofeng; Wang, Jing; Vellano, Christopher P; Marszalek, Joseph R; Bertilaccio, Maria Teresa Sabrina; Gandhi, Varsha
白血病
细胞生物学
发表日期：2021
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Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers

PARP和MEK抑制剂的合理联合治疗可有效弥补RAS突变癌症的治疗缺陷。

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aal5148
Sun, Chaoyang; Fang, Yong; Yin, Jun; Chen, Jian; Ju, Zhenlin; Zhang, Dong; Chen, Xiaohua; Vellano, Christopher P; Jeong, Kang Jin; Ng, Patrick Kwok-Shing; Eterovic, Agda Karina B; Bhola, Neil H; Lu, Yiling; Westin, Shannon N; Grandis, Jennifer R; Lin, Shiaw-Yih; Scott, Kenneth L; Peng, Guang; Brugge, Joan; Mills, Gordon B
PARP
RAS
肿瘤
肿瘤免疫
发表日期：2017
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Autotaxin, a lysophospholipase D with pleomorphic effects in oncogenesis and cancer progression

自泌素是一种溶血磷脂酶D，在肿瘤发生和癌症进展中具有多形性作用。

期刊:Journal of Lipid Research
影响因子:4.1
doi:10.1194/jlr.R060020
Federico, Lorenzo; Jeong, Kang Jin; Vellano, Christopher P; Mills, Gordon B
肿瘤
肿瘤免疫
发表日期：2016
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Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by Gαi1 and Gαi-linked G protein-coupled receptors

活细胞中 G 蛋白信号调节因子 14 (RGS14)·H-Ras 信号复合物的组装和功能受 Gαi1 和 Gαi 连接的 G 蛋白偶联受体的调控。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M112.440057
Vellano, Christopher P; Brown, Nicole E; Blumer, Joe B; Hepler, John R
信号转导
细胞生物学
发表日期：2013
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Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loop

蛋白酶激活受体1 (PAR1) 与G(q/11) 的偶联，而非与G(i/o) 或G(12/13) 的偶联，是由受体第二胞内环内的特定氨基酸介导的。

期刊:Cellular Signalling
影响因子:3.7
doi:10.1016/j.cellsig.2012.01.011
McCoy, Kelly L; Gyoneva, Stefka; Vellano, Christopher P; Smrcka, Alan V; Traynelis, Stephen F; Hepler, John R
信号转导
发表日期：2012
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RGS14 at the interface of hippocampal signaling and synaptic plasticity

RGS14 位于海马信号传导和突触可塑性的交汇处

期刊:Trends in Pharmacological Sciences
影响因子:19.9
doi:10.1016/j.tips.2011.07.005
Vellano, Christopher P; Lee, Sarah Emerson; Dudek, Serena M; Hepler, John R
信号转导
神经科学
发表日期：2011
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RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

RGS14 是一种天然的 CA2 神经元突触可塑性以及海马体学习和记忆的抑制因子。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1005362107
Lee, Sarah Emerson; Simons, Stephen B; Heldt, Scott A; Zhao, Meilan; Schroeder, Jason P; Vellano, Christopher P; Cowan, D Patrick; Ramineni, Suneela; Yates, Cindee K; Feng, Yue; Smith, Yoland; Sweatt, J David; Weinshenker, David; Ressler, Kerry J; Dudek, Serena M; Hepler, John R
神经科学
发表日期：2010
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