日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Separate transcription and splicing gene networks are linked and coordinated by the pRb-E2F pathway.

独立的转录和剪接基因网络通过 pRb-E2F 通路连接和协调。

Carr Simon M, Liu Geng, Barczak Wojciech, Syffudin Hasan, Munro Shonagh, Reyna-Jeldes Denise, Vendrell Iolanda, Kessler Benedikt, Cribbs Adam P, Kanapin Alexander, Samsonova Anastasia, La Thangue Nicholas B

Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles

追踪人类iPSC-小胶质细胞中的tau蛋白和细胞反应:从摄取到可播种分泌,包括在细胞外囊泡中

Karabova, Maria Kreger; Del Ser-Badia, Anna; Hedegaard, Anne; Washer, Sam J; Baykam, Zeynep; O'Brien, Darragh P; Vendrell, Iolanda; Hester, Svenja S; Fischer, Roman; Johnson, Errin; Melia, Charlotte E; Matthews-Palmer, Teige R S; Matadeen, Rishi; Santambrogio, Alessia; Metrick, Michael A 2nd; Vendruscolo, Michele; Keeling, Sophie; Cheam, Kimberly Ai Xian; McEwan, William A; Kosik, Kenneth S; Day, Theresa A; James, William S; Cowley, Sally A

Pervasive phenotypic effects of FBXO42 are promoted by regulation of PP4 phosphatase.

FBXO42 的广泛表型效应是通过调节 PP4 磷酸酶而促进的。

Yang Hongbin, Smith Paul, Ma Yingying, Southworth Emily, Gopala Krishna Varun, Salerno Beatrice, Rowland Joseph, Loftus Alexander E P, Grieco Domenico, Vendrell Iolanda, Fischer Roman, Kessler Benedikt M, D'Angiolella Vincenzo

Proteomic Snapshots of Structural Cross-Linking Rearrangements in Ca(2+)/Calmodulin-Dependent Kinase-1-Delta Associated with Its Regulation by ATP, Ca(2+)/Calmodulin, and Reduction Potential

Ca(2+)/钙调蛋白依赖性激酶-1-δ的结构交联重排及其与ATP、Ca(2+)/钙调蛋白和还原电位调控相关的蛋白质组学快照

Mbabala, Lutho; Tshililo, Ndivhuwo O; Vlok, Mare; Vendrell, Iolanda; Fischer, Roman; Tabb, David L; Trieber, Catharine A; Adra, Trixie Rae C; Overduin, Michael; Butterworth, Sam; Kenyon, Colin P

Tetraspanin-based immunocapture for high-depth proteomic profiling of extracellular vesicles from cerebrospinal fluid for biomarker discovery

基于四跨膜蛋白的免疫捕获技术用于脑脊液细胞外囊泡的高深度蛋白质组学分析,以发现生物标志物

Dellar, Elizabeth R; Vendrell, Iolanda; Fischer, Roman; Thompson, Alexander G

Pleural fluid proteomics from patients with pleural infection shows signatures of diverse neutrophilic responses: The Oxford Pleural Infection Endotyping Study (TORPIDS-2)

胸膜感染患者的胸膜液蛋白质组学显示出多种中性粒细胞反应的特征:牛津胸膜感染内型研究(TORPIDS-2)

Kanellakis, Nikolaos I; Antoun, Elie; Cano-Gamez, Kiki; Chu, Julia; Manoharan, Nikita; Berridge, Georgina; Vendrell, Iolanda; Zhang, Zheqing; Corcoran, John P; Elsheikh, Alguili; Dong, Tao; Fischer, Roman; Whalley, Justin P; Knight, Julian C; Rahman, Najib M

A cytoplasmic motif in HLA-E that drives clathrin-mediated endocytosis and VCP-associated postendocytic trafficking.

HLA-E 中的胞质基序驱动网格蛋白介导的内吞作用和 VCP 相关的内吞后运输。

He Wanlin, Damianou Andreas, Vendrell Iolanda, Früh Klaus, Yin Daowen I, Brodsky Frances M, Kessler Benedikt M, Brackenridge Simon, Borrow Persephone, Gillespie Geraldine M, McMichael Andrew J

Elevated Cerebrospinal Fluid Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 in Asymptomatic C9orf72 Hexanucleotide Repeat Expansion Carriers

无症状C9orf72六核苷酸重复序列扩增携带者脑脊液中泛素羧基末端水解酶同工酶L1水平升高

Dellar, Elizabeth R; Vendrell, Iolanda; Amein, Benazir; Lester, David G; Edmond, Evan C; Yoganathan, Katie; Dharmadasa, Thanuja; Sogorb-Esteve, Aitana; Fischer, Roman; Talbot, Kevin; Rohrer, Jonathan D; Turner, Martin R; Thompson, Alexander G

Acidosis attenuates the hypoxic stabilization of HIF-1α by activating lysosomal degradation.

酸中毒通过激活溶酶体降解来减弱缺氧对 HIF-1α 的稳定作用

White Bobby, Wang Zhenyi, Dean Matthew, Michl Johanna, Nieora Natalia, Flannery Sarah, Vendrell Iolanda, Fischer Roman, Hulikova Alzbeta, Swietach Pawel

TDP-43 pathology is associated with divergent protein profiles in ALS brain and spinal cord

TDP-43病理与ALS脑和脊髓中不同的蛋白质谱相关

Feneberg, Emily; Thompson, Alexander G; Charles, Philip D; Vendrell, Iolanda; Kessler, Benedikt M; Fischer, Roman; Ansorge, Olaf; Gray, Elizabeth; Talbot, Kevin; Turner, Martin R