日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Molecular basis of ligand binding and receptor activation at the human A(3) adenosine receptor.

人类A(3)腺苷受体配体结合和受体激活的分子基础

Zhang Liudi, Mobbs Jesse I, Bennetts Felix M, Venugopal Hariprasad, Nguyen Anh T N, Christopoulos Arthur, van der Es Daan, Heitman Laura H, May Lauren T, Glukhova Alisa, Thal David M

MORC2 is a phosphorylation-dependent DNA compaction machine.

MORC2 是一种磷酸化依赖的 DNA 压缩机器

Tan Winnie, Park Jeongveen, Venugopal Hariprasad, Lou Jieqiong, Dias Prabavi Shayana, Baldoni Pedro L, Moon Kyoung-Wook, Dite Toby A, Keenan Christine R, Gurzau Alexandra D, Lee Joonyoung, Johanson Timothy M, Leis Andrew, Yousef Jumana, Vaibhav Vineet, Dagley Laura F, Ang Ching-Seng, Corso Laura D, Davidovich Chen, Vervoort Stephin J, Smyth Gordon K, Blewitt Marnie E, Allan Rhys S, Hinde Elizabeth, D'Arcy Sheena, Ryu Je-Kyung, Shakeel Shabih

Cryo-EM reveals an extrahelical allosteric binding site at the M(5) mAChR.

冷冻电镜揭示了 M(5) mAChR 的螺旋外变构结合位点

Burger Wessel A C, Mobbs Jesse I, Rana Bhavika, Wang Jinan, Joshi Keya, Gentry Patrick R, Yeasmin Mahmuda, Venugopal Hariprasad, Bender Aaron M, Lindsley Craig W, Miao Yinglong, Christopoulos Arthur, Valant Celine, Thal David M

High-resolution cryo-EM using a common LaB(6) 120-keV electron microscope equipped with a sub-200-keV direct electron detector

利用配备亚200 keV直接电子探测器的普通LaB<sub>6</sub> 120 keV电子显微镜进行高分辨率冷冻电镜成像。

Venugopal, Hariprasad; Mobbs, Jesse; Taveneau, Cyntia; Fox, Daniel R; Vuckovic, Ziva; Gulati, Sahil; Knott, Gavin; Grinter, Rhys; Thal, David; Mick, Stephen; Czarnik, Cory; Ramm, Georg

Structural basis of modified ligand selectivity from N-terminal PAC1R alternative splicing

PAC1R N端选择性剪接修饰配体选择性的结构基础

Lu, Jessica J; Deganutti, Giuseppe; Li, Miaomiao; Humphrys, Laura J; Li, Yandi; Nettleton, Theodore J; Venugopal, Hariprasad; Julita, Villy; Christopoulos, George; Reynolds, Christopher A; Sexton, Patrick M; Wootten, Denise; Zhao, Peishen; Piper, Sarah J

Structural basis for Porcupine inhibition

豪猪抑制的结构基础

Black, Katrina A; Mobbs, Jesse I; Venugopal, Hariprasad; Dite, Toby A; Leis, Andrew; Wong, Lilian Ll; Dagley, Laura F; Thal, David M; Glukhova, Alisa

Structure-guided allosteric modulation of the delta opioid receptor

结构导向的δ阿片受体变构调节

Mobbs, Jesse I; Nguyen, M Deborah; Deo, Owindeep; Bartuzi, Damian; Venugopal, Hariprasad; Alvi, Sadia; Pham, Vi; Barnes, Nick; Christopoulos, Arthur; Poole, Daniel P; Carbone, Simona E; Jörg, Manuela; Capuano, Ben; Carlsson, Jens; Gondin, Arisbel B; Scammells, Peter J; Valant, Celine; Thal, David M

Cryo-EM reveals a new allosteric binding site at the M(5) mAChR.

冷冻电镜揭示了 M(5) mAChR 上的一个新的变构结合位点

Burger Wessel A C, Mobbs Jesse I, Rana Bhavika, Wang Jinan, Joshi Keya, Gentry Patrick R, Yeasmin Mahmuda, Venugopal Hariprasad, Bender Aaron M, Lindsley Craig W, Miao Yinglong, Christopoulos Arthur, Valant Celine, Thal David M

Structural insights into the human P2X1 receptor and ligand interactions

人类P2X1受体及其配体相互作用的结构解析

Bennetts, Felix M; Venugopal, Hariprasad; Glukhova, Alisa; Mobbs, Jesse I; Ventura, Sabatino; Thal, David M

The structure of an infectious immature flavivirus redefines viral architecture and maturation

一种具有感染性的未成熟黄病毒的结构重新定义了病毒的结构和成熟过程。

Newton, Natalee D; Hardy, Joshua M; Modhiran, Naphak; Hugo, Leon E; Amarilla, Alberto A; Bibby, Summa; Venugopal, Hariprasad; Harrison, Jessica J; Traves, Renee J; Hall, Roy A; Hobson-Peters, Jody; Coulibaly, Fasséli; Watterson, Daniel