日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacologically increasing cGMP improves proteostasis and reduces neuropathy in mouse models of CMT1

药理学上增加 cGMP 可改善 CMT1 小鼠模型中的蛋白质稳态并减少神经病变

Seth M Moore, Joseph Gawron, Mckayla Stevens, Leandro N Marziali, Emmanuel S Buys, G Todd Milne, Maria Laura Feltri, Jordan J S VerPlank

Knockout of PA200 improves proteasomal degradation and myelination in a proteotoxic neuropathy

敲除PA200可改善蛋白毒性神经病变中的蛋白酶体降解和髓鞘形成。

Jordan Js VerPlank ,Joseph M Gawron ,Nicholas J Silvestri ,Lawrence Wrabetz ,Maria Laura Feltri

Raising cGMP restores proteasome function and myelination in mice with a proteotoxic neuropathy

提高 cGMP 可恢复患有蛋白毒性神经病的小鼠的蛋白酶体功能和髓鞘形成

Jordan J S VerPlank, Joseph Gawron, Nicholas J Silvestri, M Laura Feltri, Lawrence Wrabetz, Alfred L Goldberg

26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation

26S蛋白酶体可被多种激素和生理状态迅速激活,这些激素和生理状态可提高cAMP水平并导致Rpn6磷酸化。

VerPlank, Jordan J S; Lokireddy, Sudarsanareddy; Zhao, Jinghui; Goldberg, Alfred L

YAP and TAZ Regulate Cc2d1b and Purβ in Schwann Cells

YAP和TAZ调控雪旺细胞中的Cc2d1b和Purβ

Belin Sophie ,Herron Jacob ,VerPlank J S Jordan ,Park Yungki ,Feltri M Laura ,Poitelon Yannick

Impairment of protein degradation and proteasome function in hereditary neuropathies

遗传性神经病中的蛋白质降解和蛋白酶体功能受损

Jordan J S VerPlank, Sudarsanareddy Lokireddy, M Laura Feltri, Alfred L Goldberg, Lawrence Wrabetz

Exploring the Regulation of Proteasome Function by Subunit Phosphorylation

探索亚基磷酸化对蛋白酶体功能的调控

Jordan J S VerPlank, Alfred L Goldberg

Regulating protein breakdown through proteasome phosphorylation

通过蛋白酶体磷酸化调节蛋白质分解

VerPlank, Jordan J S; Goldberg, Alfred L

APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases

APOL1肾病风险变异通过消耗细胞钾和诱导应激激活蛋白激酶而导致细胞毒性。

Olabisi, Opeyemi A; Zhang, Jia-Yue; VerPlank, Lynn; Zahler, Nathan; DiBartolo, Salvatore 3rd; Heneghan, John F; Schlöndorff, Johannes S; Suh, Jung Hee; Yan, Paul; Alper, Seth L; Friedman, David J; Pollak, Martin R

Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation

降低 NADPH 氧化酶 2 活性作为抑制过氧亚硝酸盐形成的策略

Jacek Zielonka, Monika Zielonka, Lynn VerPlank, Gang Cheng, Micael Hardy, Olivier Ouari, Mehmet Menaf Ayhan, Radosław Podsiadły, Adam Sikora, J David Lambeth, Balaraman Kalyanaraman