APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases
APOL1肾病风险变异通过消耗细胞钾和诱导应激激活蛋白激酶而导致细胞毒性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1522913113
Olabisi, Opeyemi A; Zhang, Jia-Yue; VerPlank, Lynn; Zahler, Nathan; DiBartolo, Salvatore 3rd; Heneghan, John F; Schlöndorff, Johannes S; Suh, Jung Hee; Yan, Paul; Alper, Seth L; Friedman, David J; Pollak, Martin R