Verbout相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Cytoprotective E-WE thrombin reduces disease severity in a murine model of relapsing-remitting multiple sclerosis

细胞保护性 E-WE 凝血酶可降低复发缓解型多发性硬化症小鼠模型的疾病严重程度

期刊:American Journal of Physiology-Cell Physiology

doi:10.1152/ajpcell.00377.2023

Norah G Verbout, Weiping Su, Peter Pham, Kelley R Jordan, Tia C L Kohs, Erik I Tucker, Owen J T McCarty, Larry S Sherman

细胞生物学

多发性硬化症

发表日期：2024

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Safety and tolerability of the protein C activator AB002 in end-stage renal disease patients on hemodialysis: a randomized phase 2 trial

蛋白C激活剂AB002在接受血液透析的终末期肾病患者中的安全性和耐受性：一项随机II期试验

doi:10.1038/s43856-024-00575-y

Verbout, Norah G; Lorentz, Christina U; Markway, Brandon D; Wallisch, Michael; Marbury, Thomas C; Di Cera, Enrico; Shatzel, Joseph J; Gruber, András; Tucker, Erik I

发表日期：2024

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Pharmacological targeting of coagulation factor XI attenuates experimental autoimmune encephalomyelitis in mice

药物靶向凝血因子XI可减轻小鼠实验性自身免疫性脑脊髓炎。

期刊:Metabolic Brain Disease

影响因子:3.5

doi:10.1007/s11011-023-01251-1

Kohs, Tia C L; Fallon, Meghan E; Oseas, Ethan C; Healy, Laura D; Tucker, Erik I; Gailani, David; McCarty, Owen J T; Vandenbark, Arthur A; Offner, Halina; Verbout, Norah G

免疫/内分泌

发表日期：2023

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E-WE thrombin, a protein C activator, reduces disease severity and spinal cord inflammation in relapsing-remitting murine experimental autoimmune encephalomyelitis

E-WE凝血酶是一种蛋白C激活剂，可减轻复发缓解型小鼠实验性自身免疫性脑脊髓炎的疾病严重程度和脊髓炎症。

doi:10.21203/rs.3.rs-2802415/v1

Verbout, Norah G; Su, Weiping; Pham, Peter; Jordan, Kelley; Kohs, Tia Cl; Tucker, Erik I; McCarty, Owen Jt; Sherman, Larry S

免疫/内分泌

发表日期：2023

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The contact activation inhibitor AB023 in heparin-free hemodialysis: results of a randomized phase 2 clinical trial

无肝素血液透析中接触激活抑制剂AB023的应用：一项随机II期临床试验的结果

影响因子:23.1

doi:10.1182/blood.2021011725

Lorentz, Christina U; Tucker, Erik I; Verbout, Norah G; Shatzel, Joseph J; Olson, Sven R; Markway, Brandon D; Wallisch, Michael; Ralle, Martina; Hinds, Monica T; McCarty, Owen J T; Gailani, David; Weitz, Jeffrey I; Gruber, András

发表日期：2021

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Thrombin generation and activity in multiple sclerosis

多发性硬化症中的凝血酶生成和活性

期刊:Metabolic Brain Disease

影响因子:3.5

doi:10.1007/s11011-020-00652-w

Jordan, Kelley R; Parra-Izquierdo, Ivan; Gruber, András; Shatzel, Joseph J; Pham, Peter; Sherman, Larry S; McCarty, Owen J T; Verbout, Norah G

多发性硬化症

发表日期：2021

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Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial

接触激活抑制剂和因子XI抗体AB023在首次人体I期试验中显示出安全、剂量依赖性的抗凝血作用。

期刊:Arteriosclerosis Thrombosis and Vascular Biology

影响因子:7.4

doi:10.1161/ATVBAHA.118.312328

Lorentz, Christina U; Verbout, Norah G; Wallisch, Michael; Hagen, Matthew W; Shatzel, Joseph J; Olson, Sven R; Puy, Cristina; Hinds, Monica T; McCarty, Owen J T; Gailani, David; Gruber, András; Tucker, Erik I

发表日期：2019

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Factor XI contributes to myocardial ischemia-reperfusion injury in mice

因子XI参与小鼠心肌缺血再灌注损伤。

期刊:Blood Advances

影响因子:7.1

doi:10.1182/bloodadvances.2017004879

Lorentz, Christina U; Verbout, Norah G; Cao, Zhiping; Liu, Lijuan; Hinds, Monica T; McCarty, Owen J T; Ivanov, Ivan; Tucker, Erik I; Gailani, David; Gruber, András

发表日期：2018

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WEDGE: an anticoagulant thrombin mutant produced by autoactivation

WEDGE：一种由自身激活产生的抗凝血凝血酶突变体

期刊:Journal of Thrombosis and Haemostasis

doi:10.1111/jth.12774

Wood, D C; Pelc, L A; Pozzi, N; Wallisch, M; Verbout, N G; Tucker, E I; Gruber, A; Di Cera, E

发表日期：2015

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Thrombin mutant W215A/E217A treatment improves neurological outcome and attenuates central nervous system damage in experimental autoimmune encephalomyelitis

凝血酶突变体W215A/E217A治疗可改善实验性自身免疫性脑脊髓炎的神经系统预后并减轻中枢神经系统损伤。

期刊:Metabolic Brain Disease

影响因子:3.5

doi:10.1007/s11011-014-9558-8

Verbout, Norah G; Yu, Xiaolin; Healy, Laura D; Phillips, Kevin G; Tucker, Erik I; Gruber, András; McCarty, Owen J T; Offner, Halina

免疫/内分泌

发表日期：2015

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