日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

AAV-Mediated Artificial miRNA Reduces Pathogenic Polyglucosan Bodies and Neuroinflammation in Adult Polyglucosan Body and Lafora Disease Mouse Models

AAV介导的人工miRNA可减少成年多聚葡萄糖体病和拉福拉病小鼠模型中的致病性多聚葡萄糖体和神经炎症

Gumusgoz, Emrah; Kasiri, Sahba; Guisso, Dikran R; Wu, Jun; Dear, Matthew; Verhalen, Brandy; Minassian, Berge A

BK Polyomavirus Requires the Mismatch Repair Pathway for DNA Damage Response Activation

BK 多瘤病毒需要错配修复途径来激活 DNA 损伤反应

Joshua L Justice, Jason M Needham, Brandy Verhalen, Mengxi Jiang, Sunnie R Thompson

Targeting Gys1 with AAV-SaCas9 Decreases Pathogenic Polyglucosan Bodies and Neuroinflammation in Adult Polyglucosan Body and Lafora Disease Mouse Models

利用 AAV-SaCas9 靶向 Gys1 可减少成年多聚葡糖体病和拉福拉病小鼠模型中的致病性多聚葡糖体和神经炎症

Gumusgoz, Emrah; Guisso, Dikran R; Kasiri, Sahba; Wu, Jun; Dear, Matthew; Verhalen, Brandy; Nitschke, Silvia; Mitra, Sharmistha; Nitschke, Felix; Minassian, Berge A

Ppp1r3d deficiency preferentially inhibits neuronal and cardiac Lafora body formation in a mouse model of the fatal epilepsy Lafora disease

Ppp1r3d 缺乏优先抑制致命性癫痫拉福拉病小鼠模型中的神经元和心脏拉福拉体形成

Lori Israelian, Silvia Nitschke, Peixiang Wang, Xiaochu Zhao, Ami M Perri, Jennifer P Y Lee, Brandy Verhalen, Felix Nitschke, Berge A Minassian

EPM2A in-frame deletion slows neurological decline in Lafora Disease

EPM2A框内缺失可延缓拉福拉病患者的神经功能衰退。

Lomax, Lysa Boissé; Verhalen, Brandy; Minassian, Berge A

Polyomavirus T Antigen Induces APOBEC3B Expression Using an LXCXE-Dependent and TP53-Independent Mechanism

多瘤病毒 T 抗原通过 LXCXE 依赖性和非 TP53 依赖性机制诱导 APOBEC3B 表达

Gabriel J Starrett, Artur A Serebrenik, Pieter A Roelofs, Jennifer L McCann, Brandy Verhalen, Matthew C Jarvis, Teneale A Stewart, Emily K Law, Annabel Krupp, Mengxi Jiang, John W M Martens, Ellen Cahir-McFarland, Paul N Span, Reuben S Harris

Lafora Disease: A Review of Molecular Mechanisms and Pathology

拉福拉病:分子机制和病理学综述

Verhalen, Brandy; Arnold, Susan; Minassian, Berge A

Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein

哺乳动物ABC转运蛋白P-糖蛋白的能量转换和交替通路

Verhalen, Brandy; Dastvan, Reza; Thangapandian, Sundarapandian; Peskova, Yelena; Koteiche, Hanane A; Nakamoto, Robert K; Tajkhorshid, Emad; Mchaourab, Hassane S

Functional Upregulation of the DNA Cytosine Deaminase APOBEC3B by Polyomaviruses

多瘤病毒对DNA胞嘧啶脱氨酶APOBEC3B的功能性上调

Verhalen, Brandy; Starrett, Gabriel J; Harris, Reuben S; Jiang, Mengxi

Viral DNA replication-dependent DNA damage response activation during BK polyomavirus infection

BK 多瘤病毒感染期间病毒 DNA 复制依赖性 DNA 损伤反应激活

Brandy Verhalen, Joshua L Justice, Michael J Imperiale, Mengxi Jiang