日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ring Distortion of Vincamine Leads to the Identification of Re-Engineered Antiplasmodial Agents

长春胺环状结构畸变导致新型抗疟疾药物的发现

Norwood, Verrill M 4th; Murillo-Solano, Claribel; Goertzen, Michael G 2nd; Brummel, Beau R; Perry, David L; Rocca, James R; Chakrabarti, Debopam; Huigens, Robert William 3rd

Re-Engineering of Yohimbine's Biological Activity through Ring Distortion: Identification and Structure-Activity Relationships of a New Class of Antiplasmodial Agents

通过环状结构畸变改造育亨宾的生物活性:一类新型抗疟疾药物的鉴定及其构效关系

Paciaroni, Nicholas G; Perry, David L 2nd; Norwood, Verrill M 4th; Murillo-Solano, Claribel; Collins, Jennifer; Tenneti, Srinivasarao; Chakrabarti, Debopam; Huigens, Robert W 3rd

Yohimbine as a Starting Point to Access Diverse Natural Product-Like Agents with Re-programmed Activities against Cancer-Relevant GPCR Targets

以育亨宾为起点,探索具有针对癌症相关GPCR靶点的活性的多种天然产物样化合物

Paciaroni, Nicholas G; Norwood, Verrill M 4th; Ratnayake, Ranjala; Luesch, Hendrik; Huigens, Robert W 3rd

A Tryptoline Ring-Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine

色氨酸环扭曲策略可从吲哚生物碱育亨宾合成复杂多样的生物活性分子。

Paciaroni, Nicholas G; Ratnayake, Ranjala; Matthews, James H; Norwood, Verrill M 4th; Arnold, Austin C; Dang, Long H; Luesch, Hendrik; Huigens, Robert W 3rd