The Deglycosylated Form of 1E12, a Monoclonal Anti-PF4 IgG, Strongly Inhibits Antibody-Triggered Cellular Activation in Vaccine-Induced Thrombotic Thrombocytopenia, and Is a Potential New Treatment for Vιττ
单克隆抗PF4 IgG抗体1E12的去糖基化形式可强效抑制疫苗诱导的血栓性血小板减少症中抗体触发的细胞活化,是一种潜在的Vιττ新疗法。
期刊:American Journal of Pathology
影响因子:3.6
doi:10.1182/blood-2021-147922
Sahali, D; Mulliez, N; Chatelet, F; Laurent-Winter, C; Citadelle, D; Roux, C; Ronco, P; Verroust, P; Vayne, Caroline; Palankar, Raghavendra; Billy, Sandra; Handtke, Stefan; Thiele, Thomas; Pouplard, Claire; Greinacher, Andreas; Gruel, Yves; Rollin, Jérôme