Profiling of the Peripheral Blood Mononuclear Cells Proteome by Shotgun Proteomics Identifies Alterations of Immune System Components, Proteolytic Balance, Autophagy, and Mitochondrial Metabolism in Glaucoma Subjects
利用鸟枪法蛋白质组学对青光眼患者外周血单核细胞蛋白质组进行分析,发现其免疫系统成分、蛋白水解平衡、自噬和线粒体代谢均发生改变。
期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.4c10035
Giammaria, Sara; Pandino, Irene; Zingale, Gabriele Antonio; Atzori, Maria Grazia; Cavaterra, Dario; Cecere, Michela; Michelessi, Manuele; Roberti, Gloria; Tanga, Lucia; Carnevale, Carmela; Vercellin, Alice Verticchio; Siesky, Brent; Harris, Alon; Grasso, Giuseppe; Bocedi, Alessio; Coletta, Massimiliano; Tundo, Grazia Raffaella; Oddone, Francesco; Sbardella, Diego
青光眼
神经科学
代谢
Autophagy
线粒体
单核细胞
细胞生物学
自噬
免疫/内分泌