日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovering a predictive metabolic signature of drug-induced structural cardiotoxicity in cardiac microtissues

发现药物诱导心脏微组织结构性心脏毒性的预测性代谢特征

Bowen, Tara J; Hall, Andrew R; Lloyd, Gavin R; Smith, Matthew J; Weber, Ralf J M; Wilson, Amanda; Pointon, Amy; Viant, Mark R

Sibling species differently distributed around a CO(2) vent show transplantation proteomic remodelling, while displaying metabolomic signatures associated with their origin

分布在二氧化碳喷口周围的不同同源物种表现出移植蛋白质组重塑,同时又显示出与其起源相关的代谢组特征。

Turner, Lucy M; Madeira, Diana; Ricevuto, Elena; Gallucci, Alexia Massa; Sommer, Ulf; Viant, Mark R; Dineshram, Ramadoss; Gambi, Maria-Cristina; Calosi, Piero

Mass spectrometry-based characterisation of the cardiac microtissue metabolome and lipidome

基于质谱的心脏微组织代谢组和脂质组表征

Bowen, Tara J; Hall, Andrew R; Southam, Andrew D; Edbali, Ossama; Weber, Ralf J M; Wilson, Amanda; Pointon, Amy; Viant, Mark R

Demonstrating the reliability of in vivo metabolomics based chemical grouping: towards best practice

论证基于体内代谢组学的化学分组的可靠性:迈向最佳实践

Viant, Mark R; Amstalden, E; Athersuch, T; Bouhifd, M; Camuzeaux, S; Crizer, D M; Driemert, P; Ebbels, T; Ekman, D; Flick, B; Giri, V; Gómez-Romero, M; Haake, V; Herold, M; Kende, A; Lai, F; Leonards, P E G; Lim, P P; Lloyd, G R; Mosley, J; Namini, C; Rice, J R; Romano, S; Sands, C; Smith, M J; Sobanski, T; Southam, A D; Swindale, L; van Ravenzwaay, B; Walk, T; Weber, R J M; Zickgraf, F M; Kamp, H

Computational approaches identify a transcriptomic fingerprint of drug-induced structural cardiotoxicity

计算方法可识别药物诱导的结构性心脏毒性的转录组特征

Au Yeung, Victoria P W; Obrezanova, Olga; Zhou, Jiarui; Yang, Hongbin; Bowen, Tara J; Ivanov, Delyan; Saffadi, Izzy; Carter, Alfie S; Subramanian, Vigneshwari; Dillmann, Inken; Hall, Andrew; Corrigan, Adam; Viant, Mark R; Pointon, Amy

A novel method to derive a human safety limit for PFOA by gene expression profiling and modelling

利用基因表达谱和建模方法推导 PFOA 人体安全限值的新方法

Silva, Arthur de Carvalho E; Loizou, George D; McNally, Kevin; Osborne, Olivia; Potter, Claire; Gott, David; Colbourne, John K; Viant, Mark R

Utilizing Omics Data for Chemical Grouping

利用组学数据进行化学分组

Viant, Mark R; Barnett, Rosemary E; Campos, Bruno; Colbourne, John K; Barnard, Marianne; Biales, Adam D; Cronin, Mark T D; Fay, Kellie A; Koehrn, Kara; McGarry, Helen F; Sachana, Magdalini; Hodges, Geoff

Applying genomics in regulatory toxicology: a report of the ECETOC workshop on omics threshold on non-adversity

基因组学在监管毒理学中的应用:ECETOC关于非逆境组学阈值研讨会的报告

Gant, Timothy W; Auerbach, Scott S; Von Bergen, Martin; Bouhifd, Mounir; Botham, Philip A; Caiment, Florian; Currie, Richard A; Harrill, Joshua; Johnson, Kamin; Li, Dongying; Rouquie, David; van Ravenzwaay, Ben; Sistare, Frank; Tralau, Tewes; Viant, Mark R; van de Laan, Jan Willem; Yauk, Carole

Microbiome function predicts amphibian chytridiomycosis disease dynamics

微生物组功能预测两栖动物壶菌病疾病动态

Bates, Kieran A; Sommer, Ulf; Hopkins, Kevin P; Shelton, Jennifer M G; Wierzbicki, Claudia; Sergeant, Christopher; Tapley, Benjamin; Michaels, Christopher J; Schmeller, Dirk S; Loyau, Adeline; Bosch, Jaime; Viant, Mark R; Harrison, Xavier A; Garner, Trenton W J; Fisher, Matthew C

Toxicity by descent: A comparative approach for chemical hazard assessment

毒性遗传:化学危害评估的比较方法

Colbourne, John K; Shaw, Joseph R; Sostare, Elena; Rivetti, Claudia; Derelle, Romain; Barnett, Rosemary; Campos, Bruno; LaLone, Carlie; Viant, Mark R; Hodges, Geoff