日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability

开发预防淀粉样β蛋白毒性和网络过度兴奋的小分子 Tau-SH3 相互作用抑制剂

Jonathan R Roth, Travis Rush, Samantha J Thompson, Adam R Aldaher, Trae B Dunn, Jacob S Mesina, J Nicholas Cochran, Nicholas R Boyle, Hunter B Dean, Zhengrong Yang, Vibha Pathak, Pedro Ruiz, Mousheng Wu, Jeremy J Day, J Robert Bostwick, Mark J Suto, Corinne E Augelli-Szafran, Erik D Roberson

Inhibitors of HIV-1 Nef-Mediated Activation of the Myeloid Src-Family Kinase Hck Block HIV-1 Replication in Macrophages and Disrupt MHC-I Downregulation

HIV-1 Nef介导的髓系Src家族激酶Hck激活抑制剂可阻断巨噬细胞中的HIV-1复制并破坏MHC-I下调

Lori A Emert-Sedlak ,Omar Moukha-Chafiq, Haibin Shi ,Shoucheng Du ,John J Alvarado ,Vibha Pathak, Samuel G Tanner, Robert N Hunter, Miranda Nebane, Li Chen ,Tatiana V Ilina ,Rieko Ishima ,Sixue Zhang, Yury V Kuzmichev ,Elizabeth R Wonderlich ,Susan M Schader ,Corinne E Augelli-Szafran, Roger G Ptak ,Thomas E Smithgall

Targeting the HuR Oncogenic Role with a New Class of Cytoplasmic Dimerization Inhibitors

利用一类新的细胞质二聚化抑制剂靶向 HuR 致癌作用

Natalia Filippova, Xiuhua Yang, Subramaniam Ananthan, Jennifer Calano, Vibha Pathak, Larry Bratton, Rakesh H Vekariya, Sixue Zhang, Edward Ofori, Emily N Hayward, David Namkoong, David K Crossman, Michael R Crowley, Peter H King, James Mobley, Louis B Nabors

Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library

通过基于核苷的库进行基于结构的虚拟筛选来鉴定 DOT1L 抑制剂

Garrett S Gibbons, Amarraj Chakraborty, Sierrah M Grigsby, Afoma C Umeano, Chenzhong Liao, Omar Moukha-Chafiq, Vibha Pathak, Bini Mathew, Young-Tae Lee, Yali Dou, Stephan C Schürer, Robert C Reynolds, Timothy S Snowden, Zaneta Nikolovska-Coleska

Preferential Inhibition of Wnt/β-Catenin Signaling by Novel Benzimidazole Compounds in Triple-Negative Breast Cancer

新型苯并咪唑化合物对三阴性乳腺癌中 Wnt/β-Catenin 信号传导的优先抑制

Abhishek Gangrade, Vibha Pathak, Corinne E Augelli-Szafran, Han-Xun Wei, Patsy Oliver, Mark Suto, Donald J Buchsbaum

SRI36160 is a specific inhibitor of Wnt/β-catenin signaling in human pancreatic and colorectal cancer cells

SRI36160 是人类胰腺癌细胞和结直肠癌细胞中 Wnt/β-catenin 信号传导的特异性抑制剂

Yonghe Li, Patsy G Oliver, Wenyan Lu, Vibha Pathak, Sivaram Sridharan, Corinne E Augelli-Szafran, Donald J Buchsbaum, Mark J Suto

Identification of quinazoline compounds as novel potent inhibitors of Wnt/β-catenin signaling in colorectal cancer cells

鉴定喹唑啉化合物作为结直肠癌细胞中 Wnt/β-catenin 信号的新型有效抑制剂

Yonghe Li, Wenyan Lu, Surendra K Saini, Omar Moukha-Chafiq, Vibha Pathak, Subramaniam Ananthan

Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branching

棒状杆菌中的脂阿拉伯甘露聚糖生物合成:两种 α(1→2)-甘露吡喃糖基转移酶 MptC 和 MptD 在甘露聚糖分支中的相互作用

Arun K Mishra, Karin Krumbach, Doris Rittmann, Ben Appelmelk, Vibha Pathak, Ashish K Pathak, Jerome Nigou, Jeroen Geurtsen, Lothar Eggeling, Gurdyal S Besra

Imidazolium cation supported solution-phase assembly of homolinear alpha(1-->6)-linked octamannoside: an efficient alternate approach for oligosaccharide synthesis

咪唑阳离子支持的溶液相组装均线性α(1→6)连接的八甘露糖苷:一种高效的寡糖合成替代方法

Yerneni, Charu K; Pathak, Vibha; Pathak, Ashish K

Concise assembly of linear alpha(1-->6)-linked octamannan fluorescent probe

简洁组装线性α(1→6)连接的八甘露聚糖荧光探针

Aqueel, Mohammad S; Pathak, Vibha; Pathak, Ashish K