日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes

反复给予去甲肾上腺素能神经毒素N-(2-氯乙基)-N-乙基-2-溴苄胺(DSP-4)可调节携带淀粉样前体蛋白和早老素-1突变转基因的小鼠的神经炎症和淀粉样斑块负荷。

Pugh, Perdita L; Vidgeon-Hart, Martin P; Ashmeade, Tracey; Culbert, Ainsley A; Seymour, Zoe; Perren, Marion J; Joyce, Flora; Bate, Simon T; Babin, Anna; Virley, David J; Richardson, Jill C; Upton, Neil; Sunter, David

Dietary antioxidants decrease serum soluble adhesion molecule (sVCAM-1, sICAM-1) but not chemokine (JE/MCP-1, KC) concentrations, and reduce atherosclerosis in C57BL but not apoE*3 Leiden mice fed an atherogenic diet.

膳食抗氧化剂可降低血清可溶性粘附分子(sVCAM-1、sICAM-1)浓度,但不会降低趋化因子(JE/MCP-1、KC)浓度,并可减少喂食致动脉粥样硬化饮食的 C57BL 小鼠(而非 apoE*3 Leiden 小鼠)的动脉粥样硬化

Murphy Nuala, Grimsditch David C, Vidgeon-Hart Martin, Groot Pieter H E, Overend Philip, Benson G Martin, Graham Annette