日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inhibition of an Aquatic Rhabdovirus Demonstrates Promise of a Broad-Spectrum Antiviral for Use in Aquaculture

抑制水生弹状病毒表明广谱抗病毒药物在水产养殖中具有应用前景

Balmer, Bethany F; Powers, Rachel L; Zhang, Ting-Hu; Lee, Jihye; Vigant, Frederic; Lee, Benhur; Jung, Michael E; Purcell, Maureen K; Snekvik, Kevin; Aguilar, Hector C

Efficient and Robust Paramyxoviridae Reverse Genetics Systems

高效且稳健的副黏病毒科反向遗传系统

Beaty, Shannon M; Park, Arnold; Won, Sohui T; Hong, Patrick; Lyons, Michael; Vigant, Frederic; Freiberg, Alexander N; tenOever, Benjamin R; Duprex, W Paul; Lee, Benhur

ISG15 deficiency and increased viral resistance in humans but not mice

ISG15 缺陷与人类而非小鼠的病毒抵抗力增强有关

Scott D Speer ,Zhi Li ,Sofija Buta ,Béatrice Payelle-Brogard ,Li Qian ,Frederic Vigant ,Erminia Rubino ,Thomas J Gardner ,Tim Wedeking ,Mark Hermann ,James Duehr ,Ozden Sanal ,Ilhan Tezcan ,Nahal Mansouri ,Payam Tabarsi ,Davood Mansouri ,Véronique Francois-Newton ,Coralie F Daussy ,Marisela R Rodriguez ,Deborah J Lenschow ,Alexander N Freiberg ,Domenico Tortorella ,Jacob Piehler ,Benhur Lee ,Adolfo García-Sastre ,Sandra Pellegrini ,Dusan Bogunovic

Nipah Virus C Protein Recruits Tsg101 to Promote the Efficient Release of Virus in an ESCRT-Dependent Pathway

尼帕病毒 C 蛋白招募 Tsg101 以促进 ESCRT 依赖性途径中病毒的有效释放

Arnold Park, Tatyana Yun, Frederic Vigant, Olivier Pernet, Sohui T Won, Brian E Dawes, Wojciech Bartkowski, Alexander N Freiberg, Benhur Lee

Sendai virus, an RNA virus with no risk of genomic integration, delivers CRISPR/Cas9 for efficient gene editing.

仙台病毒是一种RNA病毒,没有基因组整合的风险,可携带CRISPR/Cas9进行高效的基因编辑。

Park Arnold, Hong Patrick, Won Sohui T, Thibault Patricia A, Vigant Frederic, Oguntuyo Kasopefoluwa Y, Taft Justin D, Lee Benhur

Broad-spectrum antivirals against viral fusion

广谱抗病毒药物对抗病毒融合

Vigant, Frederic; Santos, Nuno C; Lee, Benhur

Efficient reverse genetics reveals genetic determinants of budding and fusogenic differences between Nipah and Hendra viruses and enables real-time monitoring of viral spread in small animal models of henipavirus infection

高效的反向遗传学揭示了尼帕病毒和亨德拉病毒之间出芽和融合差异的遗传决定因素,并能够实时监测亨德拉病毒感染小动物模型中的病毒传播

Tatyana Yun, Arnold Park, Terence E Hill, Olivier Pernet, Shannon M Beaty, Terry L Juelich, Jennifer K Smith, Lihong Zhang, Yao E Wang, Frederic Vigant, Junling Gao, Ping Wu, Benhur Lee, Alexander N Freiberg

Hexon modification to improve the activity of oncolytic adenovirus vectors against neoplastic and stromal cells in pancreatic cancer

六邻体修饰提高溶瘤腺病毒载体对抗胰腺癌肿瘤细胞和基质细胞的活性

Tanja Lucas, Karim Benihoud, Frédéric Vigant, Christoph Q Schmidt, Andreas Wortmann, Max G Bachem, Thomas Simmet, Stefan Kochanek

A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion

靶向病毒-细胞融合的广谱抗病毒药物的机制范式

Vigant, Frederic; Lee, Jihye; Hollmann, Axel; Tanner, Lukas B; Akyol Ataman, Zeynep; Yun, Tatyana; Shui, Guanghou; Aguilar, Hector C; Zhang, Dong; Meriwether, David; Roman-Sosa, Gleyder; Robinson, Lindsey R; Juelich, Terry L; Buczkowski, Hubert; Chou, Sunwen; Castanho, Miguel A R B; Wolf, Mike C; Smith, Jennifer K; Banyard, Ashley; Kielian, Margaret; Reddy, Srinivasa; Wenk, Markus R; Selke, Matthias; Santos, Nuno C; Freiberg, Alexander N; Jung, Michael E; Lee, Benhur

Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo

尼帕病毒包膜假型慢病毒在体外可有效靶向 EphrinB2 阳性干细胞群,并在体内给药时绕过肝沉降

Karina Palomares, Frederic Vigant, Ben Van Handel, Olivier Pernet, Kelechi Chikere, Patrick Hong, Sean P Sherman, Michaela Patterson, Dong Sung An, William E Lowry, Hanna K A Mikkola, Kouki Morizono, April D Pyle, Benhur Lee