A gut-on-a-chip incorporating human faecal samples and peristalsis predicts responses to immune checkpoint inhibitors for melanoma.
将人类粪便样本和肠蠕动数据整合到芯片上的肠道模型可以预测黑色素瘤对免疫检查点抑制剂的反应
期刊:Nature Biomedical Engineering
影响因子:26.6
doi:10.1038/s41551-024-01318-z
Ballerini Mattia, Galiè Serena, Tyagi Punit, Catozzi Carlotta, Raji Hariam, Nabinejad Amir, Macandog Angeli D G, Cordiale Alessandro, Slivinschi Bianca Ionela, Kugiejko Karol K, Freisa Martina, Occhetta Paola, Wargo Jennifer A, Ferrucci Pier F, Cocorocchio Emilia, Segata Nicola, Vignati Andrea, Morgun Andrey, Deleidi Michela, Manzo Teresa, Rasponi Marco, Nezi Luigi
肿瘤
黑色素瘤
Checkpoint
Human
肠道菌群
