Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics
自上而下蛋白质组学研究揭示,不同的肥厚型心肌病基因型导致趋同的肌节蛋白异构体谱。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2006764117
Tucholski, Trisha; Cai, Wenxuan; Gregorich, Zachery R; Bayne, Elizabeth F; Mitchell, Stanford D; McIlwain, Sean J; de Lange, Willem J; Wrobbel, Max; Karp, Hannah; Hite, Zachary; Vikhorev, Petr G; Marston, Steven B; Lal, Sean; Li, Amy; Dos Remedios, Cristobal; Kohmoto, Takushi; Hermsen, Joshua; Ralphe, J Carter; Kamp, Timothy J; Moss, Richard L; Ge, Ying