日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics

自上而下蛋白质组学研究揭示,不同的肥厚型心肌病基因型导致趋同的肌节蛋白异构体谱。

Tucholski, Trisha; Cai, Wenxuan; Gregorich, Zachery R; Bayne, Elizabeth F; Mitchell, Stanford D; McIlwain, Sean J; de Lange, Willem J; Wrobbel, Max; Karp, Hannah; Hite, Zachary; Vikhorev, Petr G; Marston, Steven B; Lal, Sean; Li, Amy; Dos Remedios, Cristobal; Kohmoto, Takushi; Hermsen, Joshua; Ralphe, J Carter; Kamp, Timothy J; Moss, Richard L; Ge, Ying

Instrumentation to study myofibril mechanics from static to artificial simulations of cardiac cycle

用于研究肌原纤维力学的仪器,涵盖从静态到心动周期人工模拟的各个阶段。

Vikhorev, Petr G; Ferenczi, Michael A; Marston, Steven B

Uncoupling of myofilament Ca2+ sensitivity from troponin I phosphorylation by mutations can be reversed by epigallocatechin-3-gallate.

肌丝 Ca2+ 敏感性与肌钙蛋白 I 磷酸化之间的突变解偶联可通过表没食子儿茶素-3-没食子酸酯逆转

Papadaki Maria, Vikhorev Petr G, Marston Steven B, Messer Andrew E

The dilated cardiomyopathy-causing mutation ACTC E361G in cardiac muscle myofibrils specifically abolishes modulation of Ca(2+) regulation by phosphorylation of troponin I

导致扩张型心肌病的ACTC E361G突变存在于心肌肌原纤维中,特异性地消除了肌钙蛋白I磷酸化对Ca(2+)调节的调控作用。

Vikhorev, Petr G; Song, Weihua; Wilkinson, Ross; Copeland, O'Neal; Messer, Andrew E; Ferenczi, Michael A; Marston, Steven B