日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Decolonizing pain and health-related research to advance research and optimize health

对疼痛和健康相关研究进行去殖民化,以推进研究并优化健康

Green, Carmen Renee; Villalta, Fernando V; Garcia-Almonte, Esmeralda E

Respiratory and Neurological Disease across Different Ethnic Groups Is Influenced by the Microbiome

不同种族人群的呼吸系统和神经系统疾病受微生物组的影响

Peace, Odiase; Rachakonda, Kartik; Kress, Miller; Villalta, Fernando; Rachakonda, Girish

Medroxyprogesterone Acetate (MPA) Enhances HIV-1 Accumulation and Release in Primary Cervical Epithelial Cells by Inhibiting Lysosomal Activity

醋酸甲羟孕酮 (MPA) 通过抑制溶酶体活性增强 HIV-1 在原代宫颈上皮细胞中的积累和释放

Jia, Xiangxu; Shao, Qiujia; Chaudhry, Ahsen R; Kinlock, Ballington L; Izban, Michael G; Zhang, Hong-Ying; Villalta, Fernando; Hildreth, James E K; Liu, Bindong

Transdisciplinary Perspectives on Precision Medicine

精准医学的跨学科视角

Myers, Hector F; Fair, Alecia M; Villalta, Fernando; Walz, Katherina; Beech, Bettina M; Scott, William K; Haas, David W

Building a Diverse Workforce and Thinkforce to Reduce Health Disparities

构建多元化的员工队伍和智囊团以减少健康差距

Yanagihara, Richard; Berry, Marla J; Carson, Monica J; Chang, Sandra P; Corliss, Heather; Cox, Marc B; Haddad, Georges; Hohmann, Christine; Kelley, Scott T; Lee, Eun Sook Yu; Link, Bruce G; Noel, Richard J Jr; Pickrel, Julie; Porter, James T; Quirk, Gregory J; Samuel, Temesgen; Stiles, Jonathan K; Sy, Angela U; Taira, Deborah A; Trepka, Mary Jo; Villalta, Fernando; Wiese, Thomas E

Trypanosoma cruzi Modulates PIWI-Interacting RNA Expression in Primary Human Cardiac Myocytes during the Early Phase of Infection

克氏锥虫在感染早期阶段调节原代人心肌细胞中PIWI相互作用RNA的表达

Rayford, Kayla J; Cooley, Ayorinde; Arun, Ashutosh; Rachakonda, Girish; Kleschenko, Yulia; Villalta, Fernando; Pratap, Siddharth; Lima, Maria F; Nde, Pius N

Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells

可卡因调控的microRNA miR-124控制神经元细胞中聚(ADP-核糖)聚合酶-1的表达

Dash, Sabyasachi; Balasubramaniam, Muthukumar; Martínez-Rivera, Freddyson J; Godino, Arthur; Peck, Emily G; Patnaik, Srinivas; Suar, Mrutyunjay; Calipari, Erin S; Nestler, Eric J; Villalta, Fernando; Dash, Chandravanu; Pandhare, Jui

Sterol 14α-Demethylase Structure-Based Optimization of Drug Candidates for Human Infections with the Protozoan Trypanosomatidae

基于甾醇14α-去甲基酶结构的药物候选物优化,用于治疗人类锥虫感染

Friggeri, Laura; Hargrove, Tatiana Y; Rachakonda, Girish; Blobaum, Anna L; Fisher, Paxtyn; de Oliveira, Gabriel Melo; da Silva, Cristiane França; Soeiro, Maria de Nazaré C; Nes, W David; Lindsley, Craig W; Villalta, Fernando; Guengerich, F Peter; Lepesheva, Galina I

Sterol 14α-Demethylase Structure-Based Design of VNI (( R)- N-(1-(2,4-Dichlorophenyl)-2-(1 H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide)) Derivatives To Target Fungal Infections: Synthesis, Biological Evaluation, and Crystallographic Analysis

基于甾醇14α-去甲基酶结构的VNI ((R)-N-(1-(2,4-二氯苯基)-2-(1H-咪唑-1-基)乙基)-4-(5-苯基-1,3,4-噁二唑-2-基)苯甲酰胺))衍生物靶向真菌感染的设计:合成、生物学评价和晶体学分析

Friggeri, Laura; Hargrove, Tatiana Y; Wawrzak, Zdzislaw; Blobaum, Anna L; Rachakonda, Girish; Lindsley, Craig W; Villalta, Fernando; Nes, W David; Botta, Maurizio; Guengerich, F Peter; Lepesheva, Galina I

Crystal Structure of the New Investigational Drug Candidate VT-1598 in Complex with Aspergillus fumigatus Sterol 14α-Demethylase Provides Insights into Its Broad-Spectrum Antifungal Activity

新药候选物VT-1598与烟曲霉甾醇14α-去甲基酶复合物的晶体结构揭示了其广谱抗真菌活性。

Hargrove, Tatiana Y; Garvey, Edward P; Hoekstra, William J; Yates, Christopher M; Wawrzak, Zdzislaw; Rachakonda, Girish; Villalta, Fernando; Lepesheva, Galina I