日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Develop a durable, memory-driven, CspZ-targeting Lyme disease vaccine by rationale adjuvant selection

通过合理的佐剂选择，开发一种持久的、记忆驱动的、靶向 CspZ 的莱姆病疫苗。

期刊:
影响因子:
doi:10.64898/2026.01.08.698480
McCarty, Miranda; Hernández, Sergio A; Malfetano, Jill; Leão, Ana Carolina; Villar, Maria Jose; Yang, Xiuli; Chen, Yi-Lin; Lee, Jungsoon; Liu, Zhuyun; Strych, Ulrich; Bottazzi, Maria Elena; Pal, Utpal; Strle, Klemen; Chen, Wen-Hsiang; Lin, Yi-Pin
微生物学
莱姆病
发表日期：2026
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Therapeutic potential of hookworm proteins in promoting regulatory immune responses to modulate Trypanosoma cruzi induced liver inflammation and oxidative stress

钩虫蛋白在促进调节性免疫反应以调节克氏锥虫引起的肝脏炎症和氧化应激方面的治疗潜力

期刊:Memorias Do Instituto Oswaldo Cruz
影响因子:
doi:10.1590/0074-02760250123
Villar, Maria Jose; Poveda, Cristina; Zhan, Bin; Gonsoulin, Maya; Jones, Kathryn M
炎症
氧化应激
炎症/感染
毒理研究
肝炎
免疫/内分泌
发表日期：2026
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Different responses involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models

在克氏锥虫急性实验模型中，涉及 Tfh 细胞的不同反应会延迟寄生虫特异性抗体的产生。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1487317
Leão, Ana Carolina; Villar, Maria Jose; Adhikari, Rakesh; Poveda, Cristina; Versteeg, Leroy; Almeida, Gregório; Hotez, Peter J; Bottazzi, Maria Elena; Jones, Kathryn M
微生物学
细胞生物学
Tfh
发表日期：2025
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A Honduran Prevalence Study on Soil-Transmitted Helminths Highlights Serological Antibodies to Tm-WAP49 as a Diagnostic Marker for Exposure to Human Trichuriasis

洪都拉斯一项关于土壤传播蠕虫的流行病学研究表明，Tm-WAP49血清抗体可作为人类鞭虫病暴露的诊断标志物。

期刊:American Journal of Tropical Medicine and Hygiene
影响因子:1.6
doi:10.4269/ajtmh.24-0514
Briggs, Neima; Versteeg, Leroy; Mejia, Rojelio; Pollet, Jeroen; Villar, Maria Jose; Zhan, Bin; Segal, Graeme; Novak, Stephanie; Lenihan, Patricia; Musgrave, Paul; Ellis, Viviana; Coello, Carol Florencia; Sastry, K Jagannadha; Craft, Joe; Hotez, Peter J; Bottazzi, Maria Elena
Human
发表日期：2025
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Heterologous mRNA-protein vaccination with Tc24 induces a robust cellular immune response against Trypanosoma cruzi, characterized by an increased level of polyfunctional CD8(+) T-cells

利用Tc24进行异源mRNA-蛋白疫苗接种可诱导针对克氏锥虫的强效细胞免疫反应，其特征是多功能CD8(+) T细胞水平升高。

期刊:Current Research in Immunology
影响因子:
doi:10.1016/j.crimmu.2023.100066
Poveda, Cristina; Leão, Ana Carolina; Mancino, Chiara; Taraballi, Francesca; Chen, Yi-Lin; Adhikari, Rakesh; Villar, Maria Jose; Kundu, Rakhi; Nguyen, Duc M; Versteeg, Leroy; Strych, Ulrich; Hotez, Peter J; Bottazzi, Maria Elena; Pollet, Jeroen; Jones, Kathryn M
T细胞
CD8
T细胞
细胞生物学
免疫/内分泌
发表日期：2023
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Immunomodulatory proteins from hookworms reduce cardiac inflammation and modulate regulatory responses in a mouse model of chronic Trypanosoma cruzi infection

钩虫的免疫调节蛋白可减轻慢性克氏锥虫感染小鼠模型中的心脏炎症并调节调节反应。

期刊:Frontiers in Parasitology
影响因子:
doi:10.3389/fpara.2023.1244604
Jones, Kathryn M; Zhan, Bin; Ernste, Keenan J; Villar, Maria Jose; Bisht, Nalini; Nguyen, Duc; Chang, Li-Yen; Poveda, Cristina; Robinson, Gonteria J; Trivedi, Akshar J; Hofferek, Colby J; Decker, William K; Konduri, Vanaja
炎症/感染
炎症
免疫/内分泌
发表日期：2023
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Yeast-expressed recombinant SARS-CoV-2 receptor binding domain RBD203-N1 as a COVID-19 protein vaccine candidate

酵母表达的重组SARS-CoV-2受体结合域RBD203-N1作为COVID-19候选蛋白疫苗

期刊:Protein Expression and Purification
影响因子:1.2
doi:10.1016/j.pep.2021.106003
Chen, Wen-Hsiang; Pollet, Jeroen; Strych, Ulrich; Lee, Jungsoon; Liu, Zhuyun; Kundu, Rakhi Tyagi; Versteeg, Leroy; Villar, Maria Jose; Adhikari, Rakesh; Wei, Junfei; Poveda, Cristina; Keegan, Brian; Bailey, Aaron Oakley; Chen, Yi-Lin; Gillespie, Portia M; Kimata, Jason T; Zhan, Bin; Hotez, Peter J; Bottazzi, Maria Elena
SARS-CoV-2
信号转导
Yeast
发表日期：2022
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SARS‑CoV-2 RBD219-N1C1: A yeast-expressed SARS-CoV-2 recombinant receptor-binding domain candidate vaccine stimulates virus neutralizing antibodies and T-cell immunity in mice.

SARS-CoV-2 RBD219-N1C1：一种酵母表达的 SARS-CoV-2 重组受体结合域候选疫苗可刺激小鼠产生病毒中和抗体和 T 细胞免疫

期刊:Human Vaccines & Immunotherapeutics
影响因子:3.5
doi:10.1080/21645515.2021.1901545
Pollet Jeroen, Chen Wen-Hsiang, Versteeg Leroy, Keegan Brian, Zhan Bin, Wei Junfei, Liu Zhuyun, Lee Jungsoon, Kundu Rahki, Adhikari Rakesh, Poveda Cristina, Villar Maria Jose, de Araujo Leao Ana Carolina, Altieri Rivera Joanne, Momin Zoha, Gillespie Portia M, Kimata Jason T, Strych Ulrich, Hotez Peter J, Bottazzi Maria Elena
细胞生物学
Yeast
发表日期：2021
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Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate.

通过基因改造设计出稳定的酵母表达的重组SARS-CoV-2受体结合域，作为COVID-19候选疫苗

期刊:Biochimica et Biophysica Acta-General Subjects
影响因子:2.2
doi:10.1016/j.bbagen.2021.129893
Chen Wen-Hsiang, Wei Junfei, Kundu Rakhi Tyagi, Adhikari Rakesh, Liu Zhuyun, Lee Jungsoon, Versteeg Leroy, Poveda Cristina, Keegan Brian, Villar Maria Jose, de Araujo Leao Ana C, Rivera Joanne Altieri, Gillespie Portia M, Pollet Jeroen, Strych Ulrich, Zhan Bin, Hotez Peter J, Bottazzi Maria Elena
炎症/感染
新冠
Yeast
发表日期：2021
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Prevalence of Intestinal Parasites in a Low-Income Texas Community

德克萨斯州低收入社区肠道寄生虫的流行情况

期刊:American Journal of Tropical Medicine and Hygiene
影响因子:1.6
doi:10.4269/ajtmh.19-0915
Singer, Rachael; Xu, Teena Huan; Herrera, Lauren Nicholas S; Villar, Maria Jose; Faust, Kasey M; Hotez, Peter J; Aiken, Abigail R A; Mejia, Rojelio
微生物学
发表日期：2020
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