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日期影响因子

Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity

基于氮杂肽的SARS-CoV-2主蛋白酶抑制剂：设计、合成、酶抑制、结构鉴定和抗病毒活性

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.5c01520

Flury, Philipp; Vishwakarma, Jyoti; Sylvester, Katharina; Higashi-Kuwata, Nobuyo; Dabrowska, Agnieszka K; Delgado, Renee; Cuell, Ashley; Basu, Rahul; Taylor, Alexander B; de Oliveira, Ellen Gonçalves; Magalhães Serafim, Mateus Sá; Qiao, Jingxin; Chen, Yan; Yang, Shengyong; O'Donoghue, Anthony J; Mitsuya, Hiroaki; Gütschow, Michael; Laufer, Stefan A; Müller, Christa E; Harris, Reuben S; Pillaiyar, Thanigaimalai

发表日期：2025

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Elucidation of the Synergistic Interaction Between Bilirubin and Casein Protein: An Integrated Spectroscopy and Computational Approach

阐明胆红素与酪蛋白之间的协同作用：一种整合光谱学和计算方法

期刊:Biomacromolecules

影响因子:5.4

doi:10.1021/acs.biomac.5c00795

Sharma, Sudhanshu; Vishwakarma, Jyoti; Czub, Jacek; Sappati, Subrahmanyam; Gavvala, Krishna

发表日期：2025

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Structural basis for varying drug resistance of SARS-CoV-2 M(pro) E166 variants

SARS-CoV-2 M(pro) E166 变体耐药性差异的结构基础

影响因子:4.7

doi:10.1128/mbio.02624-24

Esler, Morgan A; Shi, Ke; Rollie, Joseph A; Delgado, Renee; Vishwakarma, Jyoti; Dabrowska, Agnieszka; Prahlad, Janani; Moghadasi, Seyed Arad; Harris, Reuben S; Aihara, Hideki

发表日期：2025

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A split luciferase system for studying coronavirus M(pro) dimerization in vitro and in living cells

用于研究冠状病毒M(pro)二聚体在体外和活细胞中的分裂荧光素酶系统

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2025.110890

Delgado, Renee; Vishwakarma, Jyoti; Sanlley Hernandez, Javier O; Tansiongco, Megan; Cuell, Ashley; Dabrowska, Agnieszka; Basu, Rahul; Schmidpeter, Philipp A M; Hu, You; Tsutakawa, Susan E; Cooley, Christina B; Amaro, Rommie E; Harris, Reuben S

细胞生物学

发表日期：2025

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A Novel Fluorescence Polarization Binding Assay for the Main Protease (M(pro)) of SARS-CoV‑2

一种用于检测SARS-CoV-2主蛋白酶(M(pro))的新型荧光偏振结合分析方法

期刊:ACS Pharmacology and Translational Science

影响因子:3.7

doi:10.1021/acsptsci.5c00463

Wyllie, Mackenzie K; Biswas, Rayhan G; Vishwakarma, Jyoti; Esler, Morgan A; Rollie, Joseph A; Aihara, Hideki; Harris, Reuben S; Harki, Daniel A

发表日期：2025

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Repurposing of approved drugs towards Nipah virus treatment: an in silico docking, molecular dynamics simulation and a MM/GBSA approach

利用计算机模拟对接、分子动力学模拟和MM/GBSA方法重新开发已批准药物用于尼帕病毒治疗

doi:10.1007/s40203-025-00371-z

Hatimuria, Madushmita; Vishwakarma, Jyoti; Takkella, Dineshbabu; Chandran, C Nikesh; Phukan, Plabana; Gavvala, Krishna; Pabbathi, Ashok

多发性骨髓瘤

发表日期：2025

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A SARS-CoV-2 entry inhibitor trimerizes to lock the spike protein in a closed conformation

SARS-CoV-2病毒入侵抑制剂三聚化，将刺突蛋白锁定在封闭构象中。

doi:10.1101/2025.11.19.689107

Mou, Huihui; Gao, Bo; Ye, Gang; Zhang, Lizhou; Saxena, Divyasha; Bu, Fan; Vishwakarma, Jyoti; Zhou, Shuo; Bayona, Claudia Ruiz; Lin, Li; Getmanenko, Yulia; Bhandari, Janarjan; Bailey, Charles C; Crynen, Gogce C; Kitzmiller, Claire E; Li, Hao; Otsuka, Yuka; Wang, Chao; Batra, Lalit; Weston, Stuart; Frieman, Matthew B; Meyerholz, David K; Scampavia, Louis; Spicer, Timothy P; Harris, Reuben S; Cameron, Michael D; Bannister, Thomas D; Zheng, Jian; Farzan, Michael; Li, Fang; Choe, Hyeryun

发表日期：2025

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Molluscum contagiosum virus protein MC089 inhibits interferon regulatory factor 3 activation.

传染性软疣病毒蛋白MC089抑制干扰素调节因子3的激活

期刊:Journal of General Virology

影响因子:4.3

doi:10.1099/jgv.0.002015

Al Hamrashdi Mariya, Sanchez Perez Carla, Haas Darya A, Vishwakarma Jyoti, Pichlmair Andreas, Bowie Andrew G, Brady Gareth

发表日期：2024

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Setomimycin as a potential molecule for COVID‑19 target: in silico approach and in vitro validation

塞托霉素作为新冠病毒潜在靶点分子：计算机模拟和体外验证

期刊:Molecular Diversity

影响因子:3.8

doi:10.1007/s11030-022-10441-5

Manhas, Ravi S; Tiwari, Harshita; Noor, Mateen; Ahmed, Ajaz; Vishwakarma, Jyoti; Tripathi, Raja B M; Ramachandran, Ravishankar; Madishetti, Sreedhar; Mukherjee, Debaraj; Nargotra, Amit; Chaubey, Asha

发表日期：2023

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AtROS1 overexpression provides evidence for epigenetic regulation of genes encoding enzymes of flavonoid biosynthesis and antioxidant pathways during salt stress in transgenic tobacco

AtROS1 过表达为转基因烟草在盐胁迫下编码黄酮类生物合成和抗氧化途径酶的基因的表观遗传调控提供了证据

期刊:Journal of Experimental Botany

影响因子:5.6

doi:10.1093/jxb/erv304

Poonam Bharti, Monika Mahajan, Ajay K Vishwakarma, Jyoti Bhardwaj, Sudesh Kumar Yadav

发表日期：2015

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