Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice.
携带与神经发育障碍相关的 TRIO 变异体的杂合子会导致小鼠在行为、神经元发育和突触传递方面出现明显的缺陷
期刊:Elife
影响因子:6.4
doi:10.7554/eLife.103620
Ishchenko Yevheniia, Jeng Amanda T, Feng Shufang, Nottoli Timothy, Manriquez-Rodriguez Cindy, Nguyen Khanh K, Carrizales Melissa G, Vitarelli Matthew J, Corcoran Ellen E, Greer Charles A, Myers Samuel A, Koleske Anthony J
