Vivasvan相关文献与解析，生知库 | 链接生命科学的每一步

Chang, Christopher R; Vykunta, Vivasvan S; Lee, Jae Hyun J; Li, Ke; Kochendoerfer, Clara; Muldoon, Joseph J; Wang, Charlotte H; Mazumder, Thomas; Sun, Yang; Goodman, Daniel B; Nyberg, William A; Liu, Chang; Allain, Vincent; Rothrock, Allison; Ye, Chun J; Marson, Alexander; Shy, Brian R; Eyquem, Justin

T细胞

EED

T细胞

Mast cells help organize the Peyer's patch niche for induction of IgA responses

肥大细胞有助于组织派氏淋巴集结的微环境，从而诱导IgA反应。

期刊:Science Immunology

影响因子:17.6

doi:10.1126/sciimmunol.adj7363

Marco De Giovanni ，Vivasvan S Vykunta ，Adi Biram ，Kevin Y Chen ，Hanna Taglinao ，Jinping An ，Dean Sheppard ，Helena Paidassi ，Jason G Cyster

Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection

使用 SEED-Selection 在多个基因座进行超高效 T 细胞重编程

期刊:

影响因子:

doi:10.1101/2024.02.06.576175

Christopher R Chang, Vivasvan S Vykunta, Daniel B Goodman, Joseph J Muldoon, William A Nyberg, Chang Liu, Vincent Allain, Allison Rothrock, Charlotte H Wang, Alexander Marson, Brian R Shy, Justin Eyquem

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

使用混合 ssDNA 修复模板和小分子混合物在原代细胞中进行高产基因组工程

期刊:Nature Biotechnology

影响因子:33.1

doi:10.1038/s41587-022-01418-8

Brian R Shy #, Vivasvan S Vykunta #, Alvin Ha, Alexis Talbot, Theodore L Roth, David N Nguyen, Wolfgang G Pfeifer, Yan Yi Chen, Franziska Blaeschke, Eric Shifrut, Shane Vedova, Murad R Mamedov, Jing-Yi Jing Chung, Hong Li, Ruby Yu, David Wu, Jeffrey Wolf, Thomas G Martin, Carlos E Castro, Lumeng Ye,

Molecular basis for potent B cell responses to antigen displayed on particles of viral size

细胞对病毒大小颗粒上抗原产生强烈反应的分子基础

期刊:Nature Immunology

影响因子:27.7

doi:10.1038/s41590-023-01597-9

Jeremy F Brooks #, Julianne Riggs #, James L Mueller, Raisa Mathenge, Wei-Yun Wholey, Alexander R Meyer, Sekou-Tidiane Yoda, Vivasvan S Vykunta, Hailyn V Nielsen, Wei Cheng, Julie Zikherman

Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes

肽介导的 CRISPR 酶递送可有效编辑原代人类淋巴细胞

期刊:Nature Biomedical Engineering

影响因子:26.8

doi:10.1038/s41551-023-01032-2

Dana V Foss #, Joseph J Muldoon #, David N Nguyen #, Daniel Carr, Srishti U Sahu, John M Hunsinger, Stacia K Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V Schanzer, Brian R Shy, Vivasvan S Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C Wilson

CRISPR-Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells

利用 CRISPR-Cas9 介导的纳米结构基因在人类原代细胞中的核转运和基因组整合

期刊:Nucleic Acids Research

影响因子:16.6

doi:10.1093/nar/gkac049

Enrique Lin-Shiao ，Wolfgang G Pfeifer ，Brian R Shy ，Mohammad Saffari Doost ，Evelyn Chen ，Vivasvan S Vykunta ，Jennifer R Hamilton ，Elizabeth C Stahl ，Diana M Lopez ，Cindy R Sandoval Espinoza ，Alexander E Deyanov ，Rachel J Lew ，Michael G Poirer ，Alexander Marson ，Carlos E Castro ，Jennifer A Doudna

细胞生物学

发表日期：2022

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Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies

CAR-T 细胞的联合筛选确定了下一代免疫疗法所需的多种免疫信号域

期刊:Science Translational Medicine

影响因子:15.8

doi:10.1126/scitranslmed.abm1463

Daniel B Goodman, Camillia S Azimi, Kendall Kearns, Alexis Talbot, Kiavash Garakani, Julie Garcia, Nisarg Patel, Byungjin Hwang, David Lee, Emily Park, Vivasvan S Vykunta, Brian R Shy, Chun Jimmie Ye, Justin Eyquem, Alexander Marson, Jeffrey A Bluestone, Kole T Roybal8

Negative feedback by NUR77/Nr4a1 restrains B cell clonal dominance during early T-dependent immune responses

NUR77/Nr4a1的负反馈抑制早期T细胞依赖性免疫反应期间B细胞克隆的优势地位

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2021.109645

Jeremy F Brooks ，Corey Tan ，James L Mueller ，Kenta Hibiya ，Ryosuke Hiwa ，Vivasvan Vykunta ，Julie Zikherman

NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limiting

当第二信号缺失或限制时，NR4A 核受体会抑制 B 细胞对抗原的反应

期刊:Nature Immunology

影响因子:27.7

doi:10.1038/s41590-020-0765-7

Corey Tan #, Ryosuke Hiwa #, James L Mueller, Vivasvan Vykunta, Kenta Hibiya, Mark Noviski, John Huizar, Jeremy F Brooks, Jose Garcia, Cheryl Heyn, Zhongmei Li, Alexander Marson, Julie Zikherman

SEED-Selection enables high-efficiency enrichment of primary T cells edited at multiple loci

SEED-Selection技术能够高效富集在多个位点编辑过的原代T细胞。

Mast cells help organize the Peyer's patch niche for induction of IgA responses

肥大细胞有助于组织派氏淋巴集结的微环境，从而诱导IgA反应。

Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection

使用 SEED-Selection 在多个基因座进行超高效 T 细胞重编程

High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails

使用混合 ssDNA 修复模板和小分子混合物在原代细胞中进行高产基因组工程

Molecular basis for potent B cell responses to antigen displayed on particles of viral size

细胞对病毒大小颗粒上抗原产生强烈反应的分子基础

Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes

肽介导的 CRISPR 酶递送可有效编辑原代人类淋巴细胞

CRISPR-Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells

利用 CRISPR-Cas9 介导的纳米结构基因在人类原代细胞中的核转运和基因组整合

Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies

CAR-T 细胞的联合筛选确定了下一代免疫疗法所需的多种免疫信号域

Negative feedback by NUR77/Nr4a1 restrains B cell clonal dominance during early T-dependent immune responses

NUR77/Nr4a1的负反馈抑制早期T细胞依赖性免疫反应期间B细胞克隆的优势地位

NR4A nuclear receptors restrain B cell responses to antigen when second signals are absent or limiting

当第二信号缺失或限制时，NR4A 核受体会抑制 B 细胞对抗原的反应