日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Population Pharmacokinetics and Exposure-Response Analyses of Momelotinib, Its Active Metabolite (M21), and Total Active Moiety in Myelofibrosis

莫美替尼、其活性代谢物 (M21) 和总活性成分在骨髓纤维化患者中的群体药代动力学和暴露-反应分析

Rich, Benjamin; Srinivasan, Meenakshi; Ho, Yu Liu; Visser, Sandra A G; Ferron-Brady, Geraldine; Vlasakakis, Georgios

Advancing Pharmacoequity Globally: Reflections from the ASCPT Development, Regulatory, and Outcomes Network

在全球范围内推进药物公平:来自ASCPT开发、监管和结果网络的思考

Jayachandran, Priya; Ladumor, Mayur K; Vlasakakis, Georgios; Riselli, Andrew; Ilic, Katarina V; van Wijk, Rob C; Elmeliegy, Mohamed; Mukker, Jatinder Kaur; Sawant-Basak, Aarti; Long, Tao; Dong, Juyao; Rayad, Noha; Zhang, Tao

Evaluation of the Effect of Momelotinib on Cardiac Repolarization: A Thorough QT Study

莫美替尼对心脏复极化影响的评估:一项全面的QT间期研究

Vlasakakis, Georgios; Alvarez, Yolanda; Hart, Timothy; Ho, Yu Liu; Ellis, Catherine

A first-in-class leucyl-tRNA synthetase inhibitor, ganfeborole, for rifampicin-susceptible tuberculosis: a phase 2a open-label, randomized trial

首个亮氨酰-tRNA合成酶抑制剂ganfeborole用于治疗利福平敏感结核病:一项2a期开放标签随机试验

Diacon, Andreas H; Barry, Clifton E 3rd; Carlton, Alex; Chen, Ray Y; Davies, Matt; de Jager, Veronique; Fletcher, Kim; Koh, Gavin C K W; Kontsevaya, Irina; Heyckendorf, Jan; Lange, Christoph; Reimann, Maja; Penman, Sophie L; Scott, Rhona; Maher-Edwards, Gareth; Tiberi, Simon; Vlasakakis, Georgios; Upton, Caryn M; Aguirre, David Barros

First-in-human study of alpibectir (BVL-GSK098), a novel potent anti-TB drug

一项针对新型强效抗结核药物 alpibectir (BVL-GSK098) 的首次人体研究

Pieren, Michel; Abáigar Gutiérrez-Solana, Ana; Antonijoan Arbós, Rosa María; Boyle, Gary W; Davila, Myriam; Davy, Maria; Gitzinger, Marc; Husband, Lisa; Martínez-Martínez, María S; Mazarro, Dolores Ochoa; Pefani, Eleni; Penman, Sophie L; Remuiñán, Modesto J; Vlasakakis, Georgios; Zeitlinger, Markus; Dale, Glenn E

Momelotinib: Mechanism of action, clinical, and translational science

莫美替尼:作用机制、临床和转化科学

Vlasakakis, Georgios; McCabe, Michael T; Ho, Yu Liu; Ferron-Brady, Geraldine; Martin, Paul; Bentley, Darren; Ellis, Catherine; Antonysamy, Mary; Visser, Sandra A G

Machine Learning and Pharmacometrics for Prediction of Pharmacokinetic Data: Differences, Similarities and Challenges Illustrated with Rifampicin

机器学习和药物计量学在药代动力学数据预测中的应用:以利福平为例阐述其异同及挑战

Keutzer, Lina; You, Huifang; Farnoud, Ali; Nyberg, Joakim; Wicha, Sebastian G; Maher-Edwards, Gareth; Vlasakakis, Georgios; Moghaddam, Gita Khalili; Svensson, Elin M; Menden, Michael P; Simonsson, Ulrika S H; On Behalf Of The Unite Tb Consortium

Target engagement and cellular fate of otelixizumab: a repeat dose escalation study of an anti-CD3ε mAb in new-onset type 1 diabetes mellitus patients

奥替利珠单抗的靶点结合和细胞命运:一项针对新发1型糖尿病患者的抗CD3ε单克隆抗体的重复剂量递增研究

Vlasakakis, Georgios; Napolitano, Antonella; Barnard, Ruth; Brown, Kim; Bullman, Jonathan; Inman, David; Keymeulen, Bart; Lanham, David; Leirens, Quentin; MacDonald, Alexander; Mezzalana, Enrica; Page, Kevin; Patel, Minesh; Savage, Caroline O; Zamuner, Stefano; van Maurik, Andre

Dose Response and Pharmacokinetics of Tofacitinib (CP-690,550), an Oral Janus Kinase Inhibitor, in the Treatment of Chronic Plaque Psoriasis

口服 Janus 激酶抑制剂托法替尼 (CP-690,550) 治疗慢性斑块状银屑病的剂量反应和药代动力学

Vlasakakis, G; Comets, E; Keunecke, A; Gueorguieva, I; Magni, P; Terranova, N; Della Pasqua, O; de Lange, E C; Kloft, C; Masimirembwa, C; Hasler, J A; van der Graaf, P H; Tan, H; Gupta, P; Harness, J; Wolk, R; Chapel, S; Menter, A; Strober, B; Langley, RG; Krishnaswami, S; Papp, KA

Cardiovascular disease: the other face of diabetes

心血管疾病:糖尿病的另一面

Vlasakakis, G; Della Pasqua, O