日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Loss of function of the zinc finger homeobox 4 gene, ZFHX4, underlies a neurodevelopmental disorder.

锌指同源框 4 基因 (ZFHX4) 功能丧失是神经发育障碍的根本原因

期刊:American Journal of Human Genetics
影响因子:8.1
doi:10.1016/j.ajhg.2025.04.008
Pérez Baca María Del Rocío, Palomares-Bralo María, Vanhooydonck Michiel, Hamerlinck Lisa, D'haene Eva, Leimbacher Sebastian, Jacobs Eva Z, De Cock Laurenz, D'haenens Erika, Dheedene Annelies, Malfait Zoë, Vantomme Lies, Silva Ananilia, Rooney Kathleen, Zhao Xiaonan, Saeidian Amir Hossein, Owen Nichole Marie, Santos-Simarro Fernando, Lleuger-Pujol Roser, García-Miñaúr Sixto, Losantos-García Itsaso, Menten Björn, Gestri Gaia, Ragge Nicola, Sadikovic Bekim, Bogaert Elke, Vleminckx Kris, Naert Thomas, Syx Delfien, Callewaert Bert, Vergult Sarah
神经科学
发表日期：2025
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Multi-omics approach dissects cis-regulatory mechanisms underlying North Carolina macular dystrophy, a retinal enhanceropathy

多组学方法解析了北卡罗来纳州黄斑营养不良症（一种视网膜增强子病变）的顺式调控机制。

期刊:American Journal of Human Genetics
影响因子:8.1
doi:10.1016/j.ajhg.2022.09.013
Van de Sompele, Stijn; Small, Kent W; Cicekdal, Munevver Burcu; Soriano, Víctor López; D'haene, Eva; Shaya, Fadi S; Agemy, Steven; Van der Snickt, Thijs; Rey, Alfredo Dueñas; Rosseel, Toon; Van Heetvelde, Mattias; Vergult, Sarah; Balikova, Irina; Bergen, Arthur A; Boon, Camiel J F; De Zaeytijd, Julie; Inglehearn, Chris F; Kousal, Bohdan; Leroy, Bart P; Rivolta, Carlo; Vaclavik, Veronika; van den Ende, Jenneke; van Schooneveld, Mary J; Gómez-Skarmeta, José Luis; Tena, Juan J; Martinez-Morales, Juan R; Liskova, Petra; Vleminckx, Kris; De Baere, Elfride
信号转导
发表日期：2022
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CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping

CRISPR-SID：通过体内依赖性映射鉴定EZH2为纤维瘤的可药物靶点

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2115116118
Naert, Thomas; Tulkens, Dieter; Van Nieuwenhuysen, Tom; Przybyl, Joanna; Demuynck, Suzan; van de Rijn, Matt; Al-Jazrawe, Mushriq; Alman, Benjamin A; Coucke, Paul J; De Leeneer, Kim; Vanhove, Christian; Savvides, Savvas N; Creytens, David; Vleminckx, Kris
EZH2
发表日期：2021
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Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer

非洲爪蟾：加入对抗血癌的舰队

期刊:Frontiers in Physiology
影响因子:3.4
doi:10.3389/fphys.2019.00048
Dimitrakopoulou, Dionysia; Tulkens, Dieter; Van Vlierberghe, Pieter; Vleminckx, Kris
白血病
肿瘤
Xenopus
肿瘤免疫
发表日期：2019
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CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis

利用 CRISPR/Cas9 介导的 rb1 和 rbl1 基因敲除导致非洲爪蟾视网膜母细胞瘤的快速且高致病性发展

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep35264
Naert, Thomas; Colpaert, Robin; Van Nieuwenhuysen, Tom; Dimitrakopoulou, Dionysia; Leoen, Jannick; Haustraete, Jurgen; Boel, Annekatrien; Steyaert, Wouter; Lepez, Trees; Deforce, Dieter; Willaert, Andy; Creytens, David; Vleminckx, Kris
Xenopus
发表日期：2016
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Fezf2 promotes neuronal differentiation through localised activation of Wnt/β-catenin signalling during forebrain development.

Fezf2 在前脑发育过程中通过局部激活 Wnt/β-catenin 信号通路促进神经元分化

期刊:Development
影响因子:3.6
doi:10.1242/dev.115691
Zhang Siwei, Li Jingjing, Lea Robert, Vleminckx Kris, Amaya Enrique
神经科学
Wnt/β-Catenin
发表日期：2014
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Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues.

Plakophilin-3 是两栖动物胚胎发育后期所必需的，在外胚层和神经组织中发挥作用

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0034342
Munoz William A, Kloc Malgorzata, Cho Kyucheol, Lee Moonsup, Hofmann Ilse, Sater Amy, Vleminckx Kris, McCrea Pierre D
神经科学
发表日期：2012
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Wnt/beta-catenin signaling is involved in the induction and maintenance of primitive hematopoiesis in the vertebrate embryo

Wnt/β-catenin信号通路参与脊椎动物胚胎原始造血的诱导和维持

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1007725107
Tran, Hong Thi; Sekkali, Belaïd; Van Imschoot, Griet; Janssens, Sylvie; Vleminckx, Kris
信号转导
Wnt/β-Catenin
发表日期：2010
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Requirement of Wnt/beta-catenin signaling in pronephric kidney development

Wnt/β-catenin信号通路在前肾发育中的作用

期刊:Mechanisms of Development
影响因子:
doi:10.1016/j.mod.2008.11.007
Lyons, Jon P; Miller, Rachel K; Zhou, Xiaolan; Weidinger, Gilbert; Deroo, Tom; Denayer, Tinneke; Park, Jae-Il; Ji, Hong; Hong, Ji Yeon; Li, Annette; Moon, Randall T; Jones, Elizabeth A; Vleminckx, Kris; Vize, Peter D; McCrea, Pierre D
信号转导
发育与干细胞
Wnt/β-Catenin
发表日期：2009
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