日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Unravelling the molecular mechanisms causal to type 2 diabetes across global populations and disease-relevant tissues

揭示全球人群和疾病相关组织中导致 2 型糖尿病的分子机制

Bocher, Ozvan; Arruda, Ana Luiza; Yoshiji, Satoshi; Zhao, Chi; Huerta-Chagoya, Alicia; Su, Chen-Yang; Yin, Xianyong; Cammann, Davis; Taylor, Henry J; Chen, Jingchun; Suzuki, Ken; Mandla, Ravi; Yang, Ta-Yu; Matsuda, Fumihiko; Mercader, Josep M; Flannick, Jason; Meigs, James B; Wood, Alexis C; Vujkovic, Marijana; Voight, Benjamin F; Spracklen, Cassandra N; Rotter, Jerome I; Morris, Andrew P; Zeggini, Eleftheria

Methylation-associated mutagenesis underlies variation in the mutation spectrum across eukaryotes

甲基化相关的诱变作用是真核生物突变谱差异的根本原因。

Ramos-Almodóvar, Fabián; Gao, Ziyue; Voight, Benjamin F; Mathieson, Iain

Expanded chromatin accessibility mapping explains genetic variation associated with complex traits in liver

扩展染色质可及性图谱解释了与肝脏复杂性状相关的遗传变异

Wenz, Brandon M; Dudek, Max F; Ramdas, Shweta; Creasy, Kate Townsend; Xin, Dong; Olthoff, Kim M; Shaked, Abraham; Rader, Daniel J; Brown, Christopher D; Voight, Benjamin F

Tonsillar expression quantitative trait loci verify and expand genetic contributors to childhood atopic diseases

扁桃体表达数量性状位点验证并扩展了儿童特应性疾病的遗传因素。

Lorenz, Kim; Yoon, Samuel; Le Coz, Carole; Zur, Karen; Wells, Andrew; Romberg, Neil; Voight, Benjamin F

Epigenetics in Abdominal Aortic Aneurysm: Mechanisms and Risk Prediction

腹主动脉瘤的表观遗传学:机制和风险预测

Yuan, Shuai; Shakt, Gabrielle; Levin, Michael G; Hartmann, Katherine; Judy, Renae; Dinatale, Tia; Voorhees, Amy; Lynch, Julie A; Pyarajan, Saiju; Levy, Daniel; Joehanes, Roby; Chang, Kyong-Mi; Tsao, Philip; Voight, Benjamin F; Jones, Gregory T; Damrauer, Scott M

A meta-analysis of chromatin-associated loci provides insights into mechanistic interpretations of trait heritability

对染色质相关位点的荟萃分析为性状遗传力的机制解释提供了见解

Dudek, Max F; Wenz, Brandon M; Voight, Benjamin F; Almasy, Laura; Grant, Struan F A

SAIGE-GPU: accelerating genome- and phenome-wide association studies using GPUs

SAIGE-GPU:利用GPU加速全基因组和全表型关联研究

Rodriguez, Alex; Kim, Youngdae; Nandi, Tarak Nath; Keat, Karl; Kumar, Rachit; Conery, Mitchell; Bhukar, Rohan; Liu, Molei; Hessington, John; Maheshwari, Ketan; Begoli, Edmon; Tourassi, Georgia; Muralidhar, Sumitra; Natarajan, Pradeep; Voight, Benjamin F; Cho, Kelly; Gaziano, John Michael; Damrauer, Scott M; Liao, Katherine P; Zhou, Wei; Huffman, Jennifer E; Verma, Anurag; Madduri, Ravi K

Evaluating Performance and Agreement of Coronary Heart Disease Polygenic Risk Scores

评估冠心病多基因风险评分的性能和一致性

Abramowitz, Sarah A; Boulier, Kristin; Keat, Karl; Cardone, Katie M; Shivakumar, Manu; DePaolo, John; Judy, Renae; Bermudez, Francisca; Mimouni, Nour; Neylan, Christopher; Kim, Dokyoon; Rader, Daniel J; Ritchie, Marylyn D; Voight, Benjamin F; Pasaniuc, Bogdan; Levin, Michael G; Damrauer, Scott M

Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum

心力衰竭的常见变异和罕见变异遗传结构在等位基因频率谱中的分布

Lee, David S M; Cardone, Kathleen M; Zhang, David Y; Tsao, Noah L; Abramowitz, Sarah; Sharma, Pranav; DePaolo, John S; Conery, Mitchell; Aragam, Krishna G; Biddinger, Kiran; Dikilitas, Ozan; Hoffman-Andrews, Lily; Judy, Renae L; Khan, Atlas; Kullo, Iftikhar J; Puckelwartz, Megan J; Reza, Nosheen; Satterfield, Benjamin A; Singhal, Pankhuri; Arany, Zoltan; Cappola, Thomas P; Carruth, Eric D; Day, Sharlene M; Do, Ron; Haggerty, Christopher M; Joseph, Jacob; McNally, Elizabeth M; Nadkarni, Girish; Owens, Anjali T; Rader, Daniel J; Ritchie, Marylyn D; Sun, Yan V; Voight, Benjamin F; Levin, Michael G; Damrauer, Scott M

The effect of type 2 diabetes genetic predisposition on non-cardiovascular comorbidities

2型糖尿病遗传易感性对非心血管合并症的影响

Arruda, Ana Luiza; Bocher, Ozvan; Taylor, Henry J; Cammann, Davis; Yoshiji, Satoshi; Yin, Xianyong; Zhao, Chi; Chen, Jingchun; Wood, Alexis C; Suzuki, Ken; Mercader, Josep M; Spracklen, Cassandra N; Meigs, James B; Vujkovic, Marijana; Smith, George Davey; Rotter, Jerome I; Voight, Benjamin F; Morris, Andrew P; Zeggini, Eleftheria