RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation
RAF 突变型黑色素瘤对 ERK2 而非 ERK1 的依赖性不同,从而支持异常 MAPK 通路激活和细胞增殖
期刊:Molecular Cancer Research
影响因子:4.1
doi:10.1158/1541-7786.MCR-20-1022
Matthew S Crowe, Tatiana Zavorotinskaya, Charles F Voliva, Matthew D Shirley, Yanqun Wang, David A Ruddy, Daniel P Rakiec, Jeffery A Engelman, Darrin D Stuart, Alyson K Freeman