日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of functional genetic components modulating toxicity response to PFOS using genome-wide CRISPR screens in HepG2/C3A cells

利用HepG2/C3A细胞中的全基因组CRISPR筛选,鉴定调控PFOS毒性反应的功能性遗传成分。

Kim, Chanhee; Tagmount, Abderrahmane; Zhu, Zhaohan; Wilson, Frances; Li, Danmeng; Ostrov, David A; Brad Barbazuk, William; Bacher, Rhonda; Vulpe, Chris D

Identification of Functional Genetic Components Modulating Toxicity Response to PFOS using Genome-wide CRISPR Screens in HepG2/C3A cells

利用HepG2/C3A细胞中的全基因组CRISPR筛选鉴定调控PFOS毒性反应的功能性遗传成分

Kim, Chanhee; Tagmount, Abderrahmane; Zhu, Zhaohan; Wilson, Frances; Li, Danmeng; Ostrov, David A; Barbazuk, W Brad; Bacher, Rhonda; Vulpe, Chris D

Identifying Toxicity Mechanisms Associated with Early Lanthanide Exposure through Multidimensional Genome-Wide Screening

通过多维全基因组筛选识别与早期镧系元素暴露相关的毒性机制

Pallares, Roger M; An, Dahlia D; Hébert, Solène; Loguinov, Alex; Proctor, Michael; Villalobos, Jonathan A; Bjornstad, Kathleen A; Rosen, Chris J; Vulpe, Chris D; Abergel, Rebecca J

Applying genome-wide CRISPR to identify known and novel genes and pathways that modulate formaldehyde toxicity

应用全基因组 CRISPR 技术鉴定已知和新的调控甲醛毒性的基因和通路

Zhao, Yun; Wei, Linqing; Tagmount, Abderrahmane; Loguinov, Alex; Sobh, Amin; Hubbard, Alan; McHale, Cliona M; Chang, Christopher J; Vulpe, Chris D; Zhang, Luoping

Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition

肥胖个体(无论是否患有2型糖尿病)的肠道微生物功能和组成存在差异。

Thingholm, Louise B; Rühlemann, Malte C; Koch, Manja; Fuqua, Brie; Laucke, Guido; Boehm, Ruwen; Bang, Corinna; Franzosa, Eric A; Hübenthal, Matthias; Rahnavard, Ali; Frost, Fabian; Lloyd-Price, Jason; Schirmer, Melanie; Lusis, Aldons J; Vulpe, Chris D; Lerch, Markus M; Homuth, Georg; Kacprowski, Tim; Schmidt, Carsten O; Nöthlings, Ute; Karlsen, Tom H; Lieb, Wolfgang; Laudes, Matthias; Franke, Andre; Huttenhower, Curtis

Functional Profiling Identifies Determinants of Arsenic Trioxide Cellular Toxicity

功能分析揭示三氧化二砷细胞毒性的决定因素

Sobh, Amin; Loguinov, Alex; Yazici, Gulce Naz; Zeidan, Rola S; Tagmount, Abderrahmane; Hejazi, Nima S; Hubbard, Alan E; Zhang, Luoping; Vulpe, Chris D

The Toxicogenome of Hyalella azteca: A Model for Sediment Ecotoxicology and Evolutionary Toxicology

阿兹特克透明藻的毒理基因组:沉积物生态毒理学和进化毒理学的模型

Poynton, Helen C; Hasenbein, Simone; Benoit, Joshua B; Sepulveda, Maria S; Poelchau, Monica F; Hughes, Daniel S T; Murali, Shwetha C; Chen, Shuai; Glastad, Karl M; Goodisman, Michael A D; Werren, John H; Vineis, Joseph H; Bowen, Jennifer L; Friedrich, Markus; Jones, Jeffery; Robertson, Hugh M; Feyereisen, René; Mechler-Hickson, Alexandra; Mathers, Nicholas; Lee, Carol Eunmi; Colbourne, John K; Biales, Adam; Johnston, J Spencer; Wellborn, Gary A; Rosendale, Andrew J; Cridge, Andrew G; Munoz-Torres, Monica C; Bain, Peter A; Manny, Austin R; Major, Kaley M; Lambert, Faith N; Vulpe, Chris D; Tuck, Padrig; Blalock, Bonnie J; Lin, Yu-Yu; Smith, Mark E; Ochoa-Acuña, Hugo; Chen, Mei-Ju May; Childers, Christopher P; Qu, Jiaxin; Dugan, Shannon; Lee, Sandra L; Chao, Hsu; Dinh, Huyen; Han, Yi; Doddapaneni, HarshaVardhan; Worley, Kim C; Muzny, Donna M; Gibbs, Richard A; Richards, Stephen

Intestinal hephaestin potentiates iron absorption in weanling, adult, and pregnant mice under physiological conditions.

在生理条件下,肠道铁蛋白酶可增强断奶小鼠、成年小鼠和怀孕小鼠对铁的吸收

Doguer Caglar, Ha Jung-Heun, Gulec Sukru, Vulpe Chris D, Anderson Gregory J, Collins James F

Editor's Highlight: High-Throughput Functional Genomics Identifies Modulators of TCE Metabolite Genotoxicity and Candidate Susceptibility Genes

编辑推荐:高通量功能基因组学鉴定出三氯乙烯代谢物遗传毒性的调节因子和候选易感基因

De La Rosa, Vanessa Y; Asfaha, Jonathan; Fasullo, Michael; Loguinov, Alex; Li, Peng; Moore, Lee E; Rothman, Nathaniel; Nakamura, Jun; Swenberg, James A; Scelo, Ghislaine; Zhang, Luoping; Smith, Martyn T; Vulpe, Chris D

Short versus long silver nanowires: a comparison of in vivo pulmonary effects post instillation

短银纳米线与长银纳米线:滴注后体内肺部效应的比较

Silva, Rona M; Xu, Jingyi; Saiki, Clare; Anderson, Donald S; Franzi, Lisa M; Vulpe, Chris D; Gilbert, Benjamin; Van Winkle, Laura S; Pinkerton, Kent E