Deconstruction of Dual-Site Tankyrase Inhibitors Provides Insights into Binding Energetics and Suggests Critical Hotspots for Ligand Optimization.
双位点坦克酶抑制剂的解构为结合能学提供了见解，并提出了配体优化的关键热点
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c02845
Sowa Sven T, Kücükdisli Murat, Mostinski Yelena, Schaller David A, Vinagreiro Carolina S, Cirillo Davide, Bosetti Chiara, Brinch Shoshy Alam, van Laar Kirsten, Wegert Anita, Leenders Ruben G G, Krauss Stefan, Waaler Jo, Volkamer Andrea, Lehtiö Lari, Nazaré Marc
