Wabitsch相关文献与解析，生知库 | 链接生命科学的每一步

Shi Yu, Cheng Kai Yan, Thi Thi Tun, Wang Yifan, Yang Yang, Cao Xiaoyun, Chhay Vanna, Shen Yujia, He Yuchen, Zhao Tianyun, Lim Yan Ting, Deik Amy, Dennis Courtney, Pierce Kerry, Bullock Kevin, Wabitsch Martin, Clish Clary B, Banks Alexander S, Sobota Radoslaw M, Cowan Chad A, Yu Haojie

发表日期：2026

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Adissp activates insulin-independent glucose disposal and energy expenditure in white fat to treat diabetes and cardiometabolic disease

Adissp 可激活白色脂肪中不依赖胰岛素的葡萄糖利用和能量消耗，从而治疗糖尿病和心血管代谢疾病。

期刊:Science Advances

影响因子:12.5

doi:10.1126/sciadv.aed2780

Huang, Lei; Liu, Pengpeng; Chen, Qingbo; Hu, Kai; Li, Shaoxian; Lee, Alexandra; Wabitsch, Martin; Zhu, Lihua Julie; Yu, Qing; Davis, Roger; Czech, Michael P; Wolfe, Scot A; Wang, Yong-Xu

Upregulation of miR-146a-5p and miR-146b-5p limits IL-1β-mediated signaling in adipose tissue during polytrauma by downregulating IRAK1

miR-146a-5p 和 miR-146b-5p 的上调通过下调 IRAK1 来限制多发性创伤期间脂肪组织中 IL-1β 介导的信号传导。

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2026.1658504

Mortsch, Antonia; Roos, Julian; Halbgebauer, Rebecca; Lupu, Ludmila; Palmer, Annette; Werberger, Anja; Stifel, Ulrich; Wabitsch, Martin; Huber-Lang, Markus; Zinngrebe, Julia; Fischer-Posovszky, Pamela

Protein-truncating variants in APBA1 in minors with severe, early-onset obesity: implications for genetic testing

APBA1基因中导致蛋白质截短的变异与严重早发性肥胖的未成年人相关：对基因检测的启示

期刊:Molecular and Cellular Pediatrics

影响因子:3.4

doi:10.1186/s40348-026-00235-2

Lerner, Joanna; Moawia, Abubakar; Zorn, Stefanie; Kloker, Simone; Klehr-Martinelli, Margit; Winner, Kay; Penfold, Denisa; Völkl, Thomas M K; Krausnick, Miriam; Siebert, Reiner; Wabitsch, Martin

Monogenic obesity due to MC4R deficiency: lessons from a multigenerational case

MC4R 缺陷引起的单基因肥胖：来自多代病例的启示

期刊:Molecular and Cellular Pediatrics

影响因子:3.4

doi:10.1186/s40348-025-00214-z

Giannopoulou, Eleni Z; Zorn, Stefanie; Schirmer, Melanie; Brandt-Heunemann, Stephanie; Schnurbein, Julia von; Nestoris, Claudia; Moawia, Abubakar; Siebert, Reiner; Denzer, Christian; Wabitsch, Martin

The conundrum in diagnosing Maturity-Onset Diabetes of the Young (MODY) in a large German pedigree with early-onset diabetes and a novel HNF1A variant

在德国一个大型家系中，诊断青年起病型糖尿病 (MODY) 面临难题，该家系患有早发性糖尿病和一种新的 HNF1A 变异体

期刊:Molecular and Cellular Pediatrics

影响因子:3.4

doi:10.1186/s40348-026-00229-0

Giannopoulou, Eleni Z; Moawia, Abubakar; Högel, Josef; Lerner, Joanna; Zorn, Stefanie; Denzer, Christian; Siebert, Reiner; Wabitsch, Martin

[Overweight and obesity in children and adolescents - inadequate quality of care from the perspective of paediatricians in Germany]

[德国儿科医生眼中的儿童和青少年超重与肥胖——医疗质量不足]

期刊:

影响因子:

doi:10.1055/a-2704-4586

Joisten, Christine; Büssenschütt, Antje; Gellhaus, Ines; Jaeschke, Robert; Kapellen, Thomas Michael; Kauth, Thomas; Knab, Katja; Röbl, Markus; Torbahn, Gabriel; Wabitsch, Martin; Weihrauch-Blüher, Susann; Wiegand, Susanna

Genome-Wide Discovery Reveals Adipose-Specific and Systemic Regulators of Insulin Resistance

全基因组发现揭示脂肪组织特异性和系统性胰岛素抵抗调节因子

期刊:

影响因子:

doi:10.64898/2026.03.31.26349822

Garcia-Urena, Mario; Toh, Pearlyn Jia Ying; Sanz Martinez, Raquel; Kaalia, Rama; Murali, Mayank; Dashti, Hesam; Jing, Yaxin; Cunha, César; Romero-Lado, María Jose; Huang, Yuejiao; Wabitsch, Martin; Claussnitzer, Melina; Kilpeläinen, Tuomas O

Estriol attenuates visceral adiposity and pulmonary artery smooth muscle cell proliferation via ERα-mediated signalling

雌三醇通过ERα介导的信号通路减弱内脏脂肪堆积和肺动脉平滑肌细胞增殖

期刊:European Heart Journal Open

影响因子:

doi:10.1093/ehjopen/oeag001

Sharma, Smriti; Dignam, Joshua P; Aitchison, Gregor; Gaw, Rosemary; Stasinopolous, Ioannis; Gebril, Ayman; Wabitsch, Martin; Andrew, Ruth; MacLean, Margaret R

Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci

冠状动脉疾病位点的细胞类型特异性表观遗传调控回路

期刊:Nature Communications

影响因子:

doi:10.1038/s41467-026-70216-6

Hecker, Dennis; Song, Xiaoning; Baumgarten, Nina; Diagel, Anastasiia; Katsaouni, Nikoletta; Li, Ling; Li, Shuangyue; Kumar Maji, Ranjan; Behjati Ardakani, Fatemeh; Ma, Lijiang; Li, Zhaolong; Moggio, Aldo; Tews, Daniel; Sager, Hendrik; Maegdefessel, Lars; Wabitsch, Martin; Björkegren, Johan L M; Schunkert, Heribert; Chen, Zhifen; Schulz, Marcel H

GPR146 in adipose tissue drives adipose-liver crosstalk and promotes hepatic steatosis in mice.

脂肪组织中的 GPR146 驱动脂肪-肝脏相互作用，并促进小鼠肝脏脂肪变性。

Adissp activates insulin-independent glucose disposal and energy expenditure in white fat to treat diabetes and cardiometabolic disease

Adissp 可激活白色脂肪中不依赖胰岛素的葡萄糖利用和能量消耗，从而治疗糖尿病和心血管代谢疾病。

Upregulation of miR-146a-5p and miR-146b-5p limits IL-1β-mediated signaling in adipose tissue during polytrauma by downregulating IRAK1

miR-146a-5p 和 miR-146b-5p 的上调通过下调 IRAK1 来限制多发性创伤期间脂肪组织中 IL-1β 介导的信号传导。

Protein-truncating variants in APBA1 in minors with severe, early-onset obesity: implications for genetic testing

APBA1基因中导致蛋白质截短的变异与严重早发性肥胖的未成年人相关：对基因检测的启示

Monogenic obesity due to MC4R deficiency: lessons from a multigenerational case

MC4R 缺陷引起的单基因肥胖：来自多代病例的启示

The conundrum in diagnosing Maturity-Onset Diabetes of the Young (MODY) in a large German pedigree with early-onset diabetes and a novel HNF1A variant

在德国一个大型家系中，诊断青年起病型糖尿病 (MODY) 面临难题，该家系患有早发性糖尿病和一种新的 HNF1A 变异体

[Overweight and obesity in children and adolescents - inadequate quality of care from the perspective of paediatricians in Germany]

[德国儿科医生眼中的儿童和青少年超重与肥胖——医疗质量不足]

Genome-Wide Discovery Reveals Adipose-Specific and Systemic Regulators of Insulin Resistance

全基因组发现揭示脂肪组织特异性和系统性胰岛素抵抗调节因子

Estriol attenuates visceral adiposity and pulmonary artery smooth muscle cell proliferation via ERα-mediated signalling

雌三醇通过ERα介导的信号通路减弱内脏脂肪堆积和肺动脉平滑肌细胞增殖

Cell type-specific epigenetic regulatory circuitry of coronary artery disease loci

冠状动脉疾病位点的细胞类型特异性表观遗传调控回路